Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07183020Enrolling by invitation
Kappa Free Light Chains in MS and CIS
This study looks at a protein called kappa free light chains (KFLC) in the spinal fluid and blood of people with multiple sclerosis (MS) or a first MS-like episode (CIS). The goal is to better understand how this protein relates to the disease, which may help with diagnosis and monitoring.
Hanover, Lower SaxonyAges 18–70 - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07183683Recruiting
Acupuncture for bladder problems in women with MS
This study tests whether stimulating acupuncture points on the lower leg can help women with multiple sclerosis who have overactive bladder symptoms like urgency, frequent urination, or leaking. It is for women with relapsing-remitting MS who are not using a catheter regularly.
Berlin, State of BerlinAges 18–60 - NCT07182656RecruitingPhase 1
Safety of CIGB-814 in healthy Chinese volunteers
This is a first-in-human study in China testing a new drug called CIGB-814 in healthy volunteers. The goal is to check how safe the drug is, how well it is tolerated, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–45 - NCT07174973Recruiting
New balance training for better stability in MS
This study tests two new balance-training programs for people with Multiple Sclerosis. One program combines balance exercises with mild electrical stimulation on the legs, while the other uses walking exercises on a treadmill with special visual feedback. Both aim to improve balance and help your brain make new connections.
Toronto, OntarioAges 18–65 - NCT07178925Recruiting
Long-term study of antiphospholipid syndrome
This trial follows patients with antiphospholipid syndrome over time to learn more about the condition. It may help researchers understand how the disease progresses and how to better manage it.
RouenAges 18–75 - NCT07183657Recruiting
Tracking inhaler use in lung disease
This study looks at how well people with COPD or asthma use their inhalers. It aims to understand common problems and find ways to improve treatment adherence.
Hradec KrálovéAges 18 years+ - NCT07183423Recruiting
New skin barrier product vs. Vaseline for dry, irritated skin
This study tests a new skin barrier product against a standard moisturizer (petrolatum) to see which works better for mild to moderate skin problems like eczema, psoriasis, or dry skin. It may help improve your skin's barrier and reduce symptoms.
Makati City, National Capital RegionAges 18 years+ - NCT07176624Recruiting
Early prone positioning and tube feeding in ICU
This study tests whether early prone positioning (lying on your stomach) and early tube feeding can help people with severe lung failure in the ICU recover faster. It's for adults with organ failure and severe ARDS who can safely be placed on their stomach.
Changchun, JilinAges 18 years+ - NCT07176546RecruitingPhase 2/Phase 3
Testing TAVNEOS for ear, nose, and throat symptoms in GPA
This trial tests a new drug called TAVNEOS (avacopan) for people with Granulomatosis with Polyangiitis (GPA) whose symptoms affect the ears, nose, or throat. The goal is to see if this drug can reduce inflammation and improve these symptoms better than current treatments.
Edison, New JerseyAges 18 years+ - NCT07179471Recruiting
Fake Carbs Practice with MiniMed 780G for Kids with T1D
This trial tests whether using a practice 'fake carbs' method helps children and teens with type 1 diabetes manage their glucose levels better with the MiniMed 780G insulin pump in auto mode.
Athens, AtticaAges 7–19 - NCT07181941RecruitingPhase 1/Phase 2
Testing lower doses of linvoseltamab for multiple myeloma
This trial tests if a lower dose of linvoseltamab can still work well for people with multiple myeloma that has come back or not responded to treatment. It aims to reduce side effects while keeping the cancer under control.
Seattle, WashingtonAges 18 years+ - NCT07180992Recruiting
Monocytes and CART cell response in multiple myeloma
This trial looks at how certain immune cells (monocytes) affect the success of CART cell therapy for multiple myeloma. It may help doctors improve treatment for future patients.
AmiensAges 18 years+ - NCT07174843RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This study tests a new type of cell therapy called CAR-T cells that target three proteins (CD19, CD22, BCMA) to treat people with autoimmune diseases that have not responded to standard treatments. The goal is to see if it can reset the immune system and reduce disease activity.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07178431RecruitingPhase 1/Phase 2
CAR T-cell therapy for worsening multiple sclerosis
This trial tests a new treatment called MB-CART2019.1, which uses your own immune cells to fight multiple sclerosis. It is for people with progressive or worsening MS who have not responded well to other treatments.
BerlinAges 18–55 - NCT07177911RecruitingPhase 1
Study of CC312 for moderate to severe lupus
This trial tests a new medicine called CC312 for people with moderate to severe lupus (SLE) that hasn't improved with standard treatments. The goal is to see if it is safe and can help control the disease.
Chengdu, SichuanAges 18–65 - NCT07182227RecruitingPhase 1/Phase 2
Gene therapy for IgA nephropathy kidney disease
This trial tests a new gene therapy called PS-002 for adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The treatment aims to reduce kidney damage, and this study will help determine if it is safe and effective.
Miami, FloridaAges 18 years+ - NCT07175493RecruitingPhase 1/Phase 2
CM336 for relapsed or refractory autoimmune cytopenia
This study tests a new drug called CM336 for people whose immune system mistakenly attacks their own blood cells (autoimmune cytopenia) and hasn't been controlled by other treatments. The goal is to see if CM336 can safely help improve blood cell counts.
Zhengzhou, HenanAges 18 years+ - NCT07179679RecruitingPhase 1
Study of a new shot for multiple myeloma
This trial tests a new injectable treatment for people with multiple myeloma that has come back or not responded to previous therapies. It aims to see if the drug is safe and effective.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07180511Enrolling by invitationPhase 3
A study of QY201 tablets for moderate to severe eczema
This trial tests a new pill called QY201 for people with moderate to severe atopic dermatitis (eczema) that hasn't responded well to creams. It aims to see if QY201 can help control itching and skin inflammation.
Hangzhou, ZhejiangAges 18–75 - NCT07175285Recruiting
Study for lupus patients not helped by steroids and 2 immunosuppressants
This trial tests a new treatment for people with active lupus who haven't responded well to steroids and at least two other immune-suppressing drugs, including a biologic. It aims to find a better option for controlling lupus symptoms.
La Jolla, CaliforniaAges 16 years+ - NCT07181369RecruitingPhase 1
Study of GTX-B001 for chronic inducible urticaria
This trial tests a new drug, GTX-B001, in healthy people and those with a type of hives called chronic inducible urticaria (specifically cold-induced or scratch-induced hives). The goal is to see if it's safe and helps control symptoms that don't respond well to standard antihistamines.
BerlinAges 18–75 - NCT06949696Recruiting
Dual-task training and cognitive rehab for MS patients
This study tests whether combining physical and mental exercises can improve walking and thinking for people with multiple sclerosis. It may help if you have mild disability and haven't had a recent relapse.
MersinAges 18–65 - NCT05863234RecruitingPhase 1/Phase 2
Safety study for aggressive NK-cell leukemia patients
This early-phase study tests a new treatment approach for people with aggressive NK-cell leukemia, focusing mainly on safety. It may be offered to patients whose disease matches the study’s specific leukemia diagnosis rules.
Hiroshima, HiroshimaAges 18–70
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.