Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT04163562RecruitingPhase 1/Phase 2
Oral peanut treatment trial for people with peanut allergy
This trial tests an oral (by mouth) immune treatment for people with confirmed peanut allergy. It aims to see whether your immune system can become less reactive to peanuts over time, while keeping you safe during testing with careful emergency planning.
Pamplona, NavarreAges 12–65 - NCT05819463Recruiting
Study care for moderate to severe atopic dermatitis
This trial looks at treatment and medical care for teens and adults with moderate to severe atopic dermatitis (eczema). It may help by testing ways to manage symptoms better based on severity and current treatment needs.
BaselAges 12 years+ - NCT06613490RecruitingEarly Phase 1
CAR NK cells for antibody syndrome and rheumatoid arthritis
This early-phase trial tests whether a new type of immune cell (CAR NK) can treat two conditions: antisynthetase antibody syndrome (a rare autoimmune disease) and rheumatoid arthritis. It's for people whose current treatments haven't worked well enough.
Nanjing, JiangsuAges 18–70 - NCT06763848Recruiting
Blood filtering for NMOSD attacks
This trial tests a blood filtering procedure called Protein A immunoadsorption for people having an acute episode of neuromyelitis optica spectrum disorder (NMOSD). It may help remove harmful antibodies from your blood and reduce symptoms.
Guangzhou, GuangdongAges 18–65 - NCT07168473RecruitingPhase 3
A study of DW1807 for year-round allergies and asthma
This trial tests a new medicine called DW1807 for people who have both year-round allergies (like dust mites or pet dander) and asthma. It aims to see if it helps control nasal symptoms and is safe to use.
SeoulAges 19 years+ - NCT07168161RecruitingPhase 3
BDB-001 for ANCA vasculitis (GPA/MPA) trial
This trial tests a new drug called BDB-001 for people with a type of blood vessel inflammation (ANCA vasculitis, specifically GPA or MPA). It aims to see if adding BDB-001 to standard treatment can help control the disease better.
Beijing, Beijing MunicipalityAges 18–75 - NCT07166211RecruitingPhase 2
Study of CM512 injection for chronic hives
This trial tests a new injection (CM512) for people with chronic spontaneous urticaria, also known as chronic hives. If you have had itchy hives for at least 6 weeks despite taking regular antihistamines, this study may help find a new treatment option.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07171983RecruitingPhase 1
Testing a new drug for rheumatoid arthritis
This trial tests a new medication (BMS-986454) for people with rheumatoid arthritis who haven't responded well enough to methotrexate. It aims to see if the drug is safe and how it works in the body.
Hyderabad, Andhra PradeshAges 18–65 - NCT07167381Recruiting
Tumor testing to find cancer treatments for Florida patients
This study tests your tumor sample to find which drugs might work best for your cancer. It is for both children and adults whose cancer has come back or not responded to treatment, and who have already tried at least one standard therapy.
Miami, FloridaAges Any age - NCT07169695RecruitingPhase 2
Comparing a new eye drop to cyclosporine for eye allergy in kids
This study tests a new eye drop (T1695) against cyclosporine for children with moderate to severe vernal keratoconjunctivitis, a type of eye allergy. It aims to see which treatment works better and is safer for reducing symptoms.
Kolkata, West BengalAges 4–17 - NCT07172360RecruitingPhase 3
Study of VC005 tablets for active ankylosing spondylitis
This trial tests a new tablet called VC005 to see if it helps reduce pain and stiffness in people with active ankylosing spondylitis. It's a phase 3 study, meaning it's one of the final steps before the drug may be approved for wider use.
Beijing, Beijing MunicipalityAges 18–70 - NCT07174102Recruiting
Looking at lung scans in rheumatoid arthritis and related diseases
This trial studies lung scans (HRCT) from patients with rheumatoid arthritis, interstitial lung disease, or connective tissue disease to better understand lung involvement. If you have one of these conditions and have had a lung CT, you may be able to help.
PragueAges 18 years+ - NCT07167680Recruiting
Fall prevention for wheelchair users with MS or spinal cord injury
This trial tests a program to help prevent falls for people with multiple sclerosis or spinal cord injury who use a wheelchair or scooter. You will learn physical skills with a care partner to stay safe.
Urbana, IllinoisAges 18 years+ - NCT07172659RecruitingPhase 2
Study of dovramilast for leprosy type 2 reaction
This study tests a new medicine called dovramilast to see if it can help people with leprosy type 2 reaction, a painful skin condition. It compares the new medicine to the standard treatment to find out if it works better or has fewer side effects.
Seattle, WashingtonAges 18 years+ - NCT07173296Recruiting
Bleaching gel application and tooth sensitivity
This study tests two different ways of applying a gentle bleaching gel to see if one causes less tooth sensitivity. It's for people who want to whiten their front teeth and have no history of sensitivity or prior whitening.
IrbidAges 18–35 - NCT07168772Recruiting
Probiotic supplement for multiple sclerosis
This study tests whether adding a probiotic supplement to your usual MS treatment (or to no treatment) can help manage relapsing-remitting multiple sclerosis. It aims to see if the probiotic is safe and beneficial as an add-on therapy.
Barcelona, BarcelonaAges 18–60 - NCT07168486Enrolling by invitationPhase 1
CAR T-cells targeting CD19, CD20, and CD22 for lymphoma
This trial tests a new type of CAR T-cell therapy that targets three proteins (CD19, CD20, and CD22) on lymphoma cells. It's for people with B-cell lymphomas that have come back or not responded to at least two prior treatments.
Baltimore, MarylandAges 18 years+ - NCT07169487RecruitingPhase 1
Methylene Blue for Side Effects of Cancer Immunotherapy
This trial tests if methylene blue can help people who develop side effects called CRS or ICANS after treatments like CAR-T cells or bispecific antibodies. It is a first-in-human study to find a safe dose.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07167693RecruitingPhase 1/Phase 2
Testing arginine for diabetic ketoacidosis in type 2 diabetes
This trial tests if an IV medicine called arginine hydrochloride can help manage diabetic ketoacidosis (DKA) in people with type 2 diabetes. It's for those who come to the ER with very high blood sugar and ketones.
Detroit, MichiganAges 18 years+ - NCT07166848Enrolling by invitation
Electrical stimulation study for dry eye from graft vs. host disease
This trial tests if gentle electrical stimulation around the eye can help relieve dry eye symptoms caused by chronic graft versus host disease (a complication after a stem cell or bone marrow transplant). It is for people with moderate to severe dry eye who have not had recent eye surgeries or certain other eye problems.
Boston, MassachusettsAges 18–75 - NCT07169500RecruitingPhase 1/Phase 2
CAR-T with or without stem cell transplant for young women with myeloma
This trial tests a new immune cell therapy (BCMA-CART) alone or combined with a stem cell transplant for women aged 18-55 with multiple myeloma. It aims to see if this treatment is safe and effective.
Tianjin, Tianjin MunicipalityAges 18–50 - NCT07166939RecruitingPhase 4
Asthma rescue inhaler study after emergency visit
This study tests a new rescue inhaler (Airsupra) for people with asthma after an emergency visit. It may help you manage your asthma at home with fewer side effects.
Cleveland, OhioAges 18–54 - NCT07173790Enrolling by invitation
Watch and Wait in Slow-Growing Lymphoma
This study looks at how people with slow-growing lymphomas (like CLL, MZL, FL, or WM) feel during watchful waiting — when they are not on active treatment. It aims to see if patients are more anxious or worried, and how to best support them.
Seoul, Gangnam-guAges 19 years+ - NCT07164768Enrolling by invitation
Thinking and mood in kids with type 1 diabetes
This study looks at how type 1 diabetes affects thinking skills and emotional health in children, teens, and young adults. Both the young person and one of their parents will answer questions together.
Pune, MaharashtraAges 10–21
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.