Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07169500RecruitingPhase 1/Phase 2
CAR-T with or without stem cell transplant for young women with myeloma
This trial tests a new immune cell therapy (BCMA-CART) alone or combined with a stem cell transplant for women aged 18-55 with multiple myeloma. It aims to see if this treatment is safe and effective.
Tianjin, Tianjin MunicipalityAges 18–50 - NCT06951074RecruitingPhase 2/Phase 3
Stem cell transplant for type 1 diabetes
This trial tests whether transplanting stem cells that can turn into insulin-producing cells helps people with type 1 diabetes manage their blood sugar. It may reduce the need for insulin injections.
CairoAges 15–18 - NCT03898596Recruiting
Monitoring a newborn’s umbilical line using ECG guidance
This trial looks at whether using heart-monitoring (ECG) can help guide placement of an umbilical vessel catheter (a special line placed through the belly button) in newborns. It may help make line placement safer and more accurate.
Palo Alto, CaliforniaAges 1 day–1 month - NCT05532566Recruiting
Tested oak tree allergy extracts for people with inhalant allergy
This trial studies how well standardized oak (Quercus ilex and Quercus robur) allergen extracts match your specific allergy. It may help refine allergy testing and treatment planning for people with oak-triggered rhinitis, eye symptoms, and/or asthma.
MadridAges 18–64 - NCT06303128RecruitingPhase 3
Testing penicillin allergy with one vs. two oral doses
This trial compares a single dose versus two doses of a penicillin-like drug to see if people who think they are allergic to penicillin can safely be told they are not allergic. It is for people with a low-risk penicillin allergy who want to find out if they can use these antibiotics in the future.
Lubbock, TexasAges 18–89 - NCT05067348RecruitingPhase 2
Tocilizumab for generalized myasthenia gravis symptoms
This trial tests whether tocilizumab can improve symptoms and safety in people with generalized myasthenia gravis (MG) who already take standard MG treatments. It may help if your weakness is still significant despite current therapy.
Beijing, Beijing MunicipalityAges 18–80 - NCT05667610Recruiting
Immune and gut diet study for peanut-allergic children
This trial studies whether an immune-supportive diet can improve gut health (gut permeability) in children with confirmed peanut or tree-nut allergy. If you join, the researchers will use allergy testing and gut-related diet approaches to see whether symptoms and gut measures change.
AmsterdamAges 3–17 - NCT05908409RecruitingPhase 1/Phase 2
Testing an investigational drug for blood cancers that came back
This Phase 1/2 trial tests IDP-121 in people with certain blood cancers that have returned or did not respond to available treatments. The goal is to find a safe dose and see whether the treatment can help control the cancer.
Santander, CantabriaAges 18 years+ - NCT06920433RecruitingEarly Phase 1
Targeted cell therapy for tough lupus with kidney involvement
This early-phase trial tests a special immune cell therapy (UCAR T-cells) that targets two proteins (CD19 and BCMA) on the surface of lupus B cells. It is for people with difficult-to-treat lupus that affects the kidneys (lupus nephritis) who have not gotten better with standard treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT06790368Recruiting
Venom allergy treatment in real-life settings
This trial tests a venom immunotherapy for people allergic to bee or wasp stings. It aims to see how well the treatment works in everyday medical practice.
Alcorcón, MadridAges 14 years+ - NCT06382844Recruiting
Better detection of tumor cells in cutaneous T-cell lymphoma
This study uses advanced blood tests (flow cytometry) to find cancer cells more accurately in people with cutaneous T-cell lymphoma. It could lead to better monitoring of your condition.
SalamancaAges 18 years+ - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT06954272Recruiting
Study of skin structure in eczema and healthy skin
This study uses special imaging to look at the structure of skin, comparing people with eczema (who have used steroid creams) to healthy volunteers. Researchers want to understand how the skin changes with eczema and its treatment.
Sheffield, South YorkshireAges 6 months+ - NCT05790785Recruiting
Tests blood vessel changes in kids soon after type 1 diabetes
This study looks at how blood vessels and blood pressure change in children soon after being diagnosed with type 1 diabetes. It may help doctors better understand early vascular risk and how to monitor it.
Vancouver, British ColumbiaAges 8–18 - NCT07162012RecruitingEarly Phase 1
Cell therapy for EBV-positive lymphoma
This trial tests a new cell therapy (TCR-T cells) for people with EBV-positive lymphoma that has not responded to standard treatments or has come back. The therapy uses your own immune cells that have been specially trained to find and attack cancer cells carrying the EBV virus.
ShanghaiAges 18–70 - NCT07155954Recruiting
Super-Resolution Ultrasound to Tell Benign from Malignant Lymph Nodes
This study uses a special high-detail ultrasound technique to better tell if lymph nodes are harmless (benign) or cancerous (malignant). It may help avoid unnecessary biopsies or surgeries in the future.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07161271Recruiting
Study on a low-flow CO2 removal device for breathing failure
This study looks back at medical records of people who used a special device (ECCO2R) in the ICU to help remove carbon dioxide from the blood. The goal is to see if the device is safe and works well for patients with breathing problems.
Hong KongAges 18 years+ - NCT07160270Recruiting
Nerve problems in Waldenström's macroglobulinemia
This study looks at how common nerve problems (peripheral neuropathy) are in people with Waldenström's macroglobulinemia (WM), and how to best diagnose them. It aims to help doctors find nerve issues earlier and improve care.
København ØAges Any age - NCT07158229Recruiting
Long-term effects of NMDAR encephalitis
This study follows adults with NMDAR encephalitis over time to understand its long-term effects. It uses online questionnaires, so you need internet access at home.
BronAges 18 years+ - NCT07162688Enrolling by invitationPhase 1/Phase 2
Omega-3 fatty acids to prevent graft-versus-host disease after stem cell transplant
This trial tests whether omega-3 fatty acids can help prevent acute graft-versus-host disease (aGVHD) in people receiving a stem cell transplant from a donor. Omega-3 may reduce inflammation and lower the chance of this serious complication.
Fuzhou, FujianAges 18–65 - NCT07163546Enrolling by invitation
Lifestyle redesign for chronic low back pain
This trial tests a person-centered lifestyle program to help people with chronic low back pain learn new ways to manage daily activities and reduce pain. It may be a good fit if you have had low back pain for at least 3 months and are looking for non-surgical support.
Ankara, AltındağAges 18–65 - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+ - NCT07159789Recruiting
Brain stimulation to improve leg weakness in MS
This study tests whether a noninvasive brain stimulation technique (rTMS) can help people with multiple sclerosis who have leg stiffness and weakness. You will receive daily sessions over two weeks to see if it improves walking and quality of life.
Gatineau, QuebecAges 18–70 - NCT07155252Recruiting
Home glucose test for type 1 diabetes screening
This study looks at whether you can do an oral glucose tolerance test at home instead of at a clinic. It is for people who have certain antibodies linked to type 1 diabetes or who were recently diagnosed with type 1 diabetes.
New Haven, ConnecticutAges 8–45
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.