Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07123454RecruitingPhase 1/Phase 2
Study of AZD4512 for relapsed or refractory B-cell lymphoma
This trial tests a new drug called AZD4512, alone or with other cancer treatments, for people whose B-cell non-Hodgkin lymphoma has come back or stopped responding to at least two prior therapies. It aims to find out if AZD4512 can help when standard options are limited.
Irvine, CaliforniaAges 18 years+ - NCT07116031RecruitingPhase 2
Belumosudil for children with chronic GVHD
This study tests a new medicine called belumosudil for children with chronic graft-versus-host disease (GVHD) that hasn't improved with at least 2 other treatments. The goal is to see if it can help control the disease and improve symptoms.
Los Angeles, CaliforniaAges 1–18 - NCT07125001Recruiting
Mango study for Hispanic/Latino teens' health
This study looks at whether eating mango every day for 12 weeks can improve gut health and heart health in Hispanic/Latino teens who are overweight. Participants will be asked to eat a mango product and take daily photos.
Davis, CaliforniaAges 12–19 - NCT07118683Recruiting
Brazilian health study for people with HIV or AIDS
This study is creating a record of chronic health conditions (like heart disease, diabetes, or high blood pressure) in people living with HIV or AIDS in Brazil. Joining helps researchers better understand and care for the health needs of people like you.
Goiânia, GoiásAges 18 years+ - NCT07116070Recruiting
Sarcopenia and muscle loss in multiple sclerosis patients
This study looks at muscle loss (sarcopenia) in people with multiple sclerosis. It aims to understand what factors are linked to muscle loss, which could help improve care.
Konya, SelcukluAges 18 years+ - NCT07118098Recruiting
Early detection of type 1 diabetes in families and friends
This study is for people ages 1 to 45 who have a close family member or friend with type 1 diabetes. It aims to detect type 1 diabetes early by screening people who may be at higher risk.
ViennaAges 1–45 - NCT07117981Recruiting
Study of second-line treatment for thyroid eye disease
This trial looks at how thyroid eye disease (inflammation behind the eyes) changes over time in people who need stronger treatments after steroids haven't worked well enough. It aims to better understand the disease and how different second-line treatments may help.
Paris, parisAges 18 years+ - NCT07117136Recruiting
Blinatumomab after standard treatment for B-ALL
This trial is studying how well the drug blinatumomab works for adults with B-cell acute lymphoblastic leukemia (B-ALL) when it is given after the first phase of treatment. It looks at patient data to understand real-world outcomes.
Jacksonville, FloridaAges 18 years+ - NCT07125365Recruiting
UK study tracking islet antibodies in children and adults
This study enrolls people with islet autoantibodies, which are early markers for type 1 diabetes. It aims to understand who develops these antibodies and how they are linked to diabetes over time. No treatment is given—you just provide blood samples and answer questions.
Oxford, OxfordshireAges 6 months–70 years - NCT07124572Recruiting
Building a Better Diagnosis System for Thyroid Eye Disease
This study aims to build a better system for diagnosing and treating thyroid-associated ophthalmopathy (a thyroid eye condition). It may help improve care for people with this disease, and also involves healthy volunteers as a comparison group.
Hangzhou, ZhejiangAges 7–90 - NCT07116460Recruiting
Air filters for asthma in low-income housing
This study tests whether air filters placed in homes can reduce asthma symptoms in children and teens living in low-income housing in Northern Manhattan and the South Bronx. If you have asthma and are between 7 and 18 years old, you may be able to join.
New York, New YorkAges 7–18 - NCT07116434Recruiting
Discovery diabetes support for teens and young adults
This study uses a smartphone app and digital stories to help teens and young adults with type 1 diabetes learn more about managing their condition and connect with others. You may join if you have had type 1 diabetes for at least a year, have a smartphone, and have an upcoming clinic visit at Vanderbilt.
Nashville, TennesseeAges 13–21 - NCT07119359Recruiting
TB and HIV prevention study for households in Uganda
This study tests whether adding HIV prevention services to routine TB household contact checks can help more people stay healthy. If you or someone you live with has TB, you may be able to join.
KampalaAges 15 years+ - NCT07125586Recruiting
Light-based test for eosinophilic nasal polyps during surgery
This study tests a new tool that uses light (spectroscopy) to instantly detect a type of nasal polyp during surgery. The goal is to help doctors identify polyps that are driven by eosinophils, which may guide better treatment choices for you.
Qingdao, ShandongAges 18–65 - NCT07123909Recruiting
Immune adsorbent therapy for dialysis patients with inflammation
This study tests a therapy that absorbs inflammatory substances from the blood during dialysis. It may help people on dialysis who have ongoing inflammation, shown by high IL-6 or CRP levels.
MoscowAges 18 years+ - NCT07123207Recruiting
Probiotic with infliximab for Crohn's disease
This study is testing whether adding a probiotic (Bacillus subtilis) to standard infliximab treatment can improve outcomes for people with active Crohn's disease. It aims to see if the probiotic helps the medication work better.
Changsha, HunanAges 18–75 - NCT07118657Recruiting
Vegan diet's effect on gut health in kids with autoimmune hepatitis
This study looks at how a vegan diet changes the bacteria in the gut and how that affects diet and disease in children with autoimmune hepatitis. Healthy children are included as a comparison group.
New Delhi, National Capital Territory of DelhiAges birth–18 years - NCT07115654RecruitingPhase 2
A bispecific antibody trial for POEMS syndrome
This trial tests a new drug, BCMA/CD3 bispecific antibody, for people with POEMS syndrome. The drug helps the immune system attack abnormal plasma cells that cause the disease. It may offer a new treatment option for those who haven't had prior anti-plasma cell therapy.
TianjinAges 18–78 - NCT04435990RecruitingPhase 3
Allergy shots for dust mites in teens and adults
This Phase 3 study tests whether dust-mite allergy treatment (likely allergy shots) can reduce allergy symptoms and improve safety. It focuses on people whose nose/eye allergy is triggered by house dust mites and who may also have controlled asthma.
Santiago de Compostela, A CoruñaAges 12–65 - NCT04898283RecruitingPhase 3
Allergy shot study for grass and cypress pollen symptoms
This phase 3 trial tests a specific allergy treatment (an “immunotherapy” shot) for people whose symptoms are triggered by grass and cypress tree pollen. It aims to see if the treatment is safer and more effective at reducing allergy symptoms over time, especially for nose/eye symptoms and some people with asthma.
Valladolid, Castille and LeónAges 12–65 - NCT06964269RecruitingPhase 4
Acthar Gel for dry eye and autoimmune disease
This trial tests a new injectable medicine, Acthar Gel, for moderate to severe dry eye and eye pain linked to autoimmune disease. It aims to see if the drug can relieve these symptoms safely.
Nashville, TennesseeAges 18–85 - NCT06966427Recruiting
Using a dosing app for insulin management
This trial studies a smartphone system that helps people with diabetes decide how much insulin to take. It is for people who use insulin injections or are starting basal insulin, and it uses a continuous glucose monitor to guide dosing.
Petah TikvaAges 6–75 - NCT07111078RecruitingPhase 1
New Flu Vaccine (Stem) with or without Booster
This trial tests a new type of flu vaccine that targets a part of the virus that doesn't change much (the stem). It is given with or without a special booster, and researchers want to see if it provides broader protection against different flu strains.
Bethesda, MarylandAges 18–50 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for x-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
Bethesda, MarylandAges 3–60
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.