Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07108387RecruitingPhase 2
Stopping or reducing tocilizumab for well-controlled giant cell arteritis
This study compares stopping tocilizumab (Actemra) completely versus reducing the dose in people whose giant cell arteritis has been well controlled for at least a year. The goal is to find out which approach keeps the disease in remission while reducing medication side effects.
Atlanta, GeorgiaAges 50 years+ - NCT07107529RecruitingPhase 2
Study of daratumumab with teclistamab or talquetamab for frail patients with newly diagnosed multiple myeloma
This trial tests a combination of drugs—daratumumab plus either teclistamab or talquetamab—for people who have just been diagnosed with multiple myeloma and are considered frail. The goal is to see if this treatment is safe and effective for those who may not be strong enough for standard therapies.
Ascoli PicenoAges 18 years+ - NCT07108088Recruiting
Walking aid study for foot and ankle weakness
This study tests a leg brace (orthosis) called NEUROSWING to see if it helps people with foot drop or other foot and ankle weakness walk faster. It is a real-world study to support coverage by French health insurance.
Hérouville-Saint-ClairAges 18 years+ - NCT07113262RecruitingPhase 3
Study of IBI311 for people with inactive thyroid eye disease
This trial tests a new medication called IBI311 for people whose thyroid eye disease is no longer active but still causes bulging eyes. It aims to see if the drug can reduce eye bulging safely.
Shenyang, LiaoningAges 18–80 - NCT07109986RecruitingPhase 1
Study of UB-VV410 for active lupus or lupus nephritis
This trial tests a new treatment, UB-VV410, for people with active systemic lupus erythematosus (SLE) or lupus nephritis (kidney inflammation caused by lupus) that hasn't responded to standard treatments. It aims to see if this therapy can help control the disease.
NanjingAges 18–65 - NCT07112144RecruitingPhase 3
DTaP vaccine trial for healthy infants aged 2 months
This trial tests a new vaccine that protects against diphtheria, tetanus, and pertussis (whooping cough). It is for healthy infants who are about 2 months old and live permanently in the area. The goal is to see if the vaccine is safe and works well.
Wenshan Zhuang and Miao Autonomous Prefecture, YunnanAges 2 months–3 months - NCT07114367RecruitingPhase 1
NB02 for relapsed non-Hodgkin's lymphoma
This trial tests a new oral drug (NB02) for people with certain types of non-Hodgkin's lymphoma that have come back or not responded to at least two prior treatments. It aims to see if the drug can shrink tumors and control the disease.
HwasunAges 19–80 - NCT07112378RecruitingPhase 3
Study of dupilumab for young children with eosinophilic esophagitis
This trial tests if dupilumab can help young children with eosinophilic esophagitis (EoE), a condition that causes swelling in the esophagus. It may reduce symptoms and improve how the esophagus heals.
Phoenix, ArizonaAges 6 months–6 years - NCT06747364Recruiting
Blood test for recent alcohol use
This study looks at a blood test that may tell how much alcohol a person has had recently, even after they've stopped drinking. It may help doctors better understand drinking patterns and health risks.
Denton, TexasAges 21 years+ - NCT05062707Recruiting
Study of early aging in young people during cancer treatment
This study looks at how “early aging” changes show up during treatment in young adults with cancer. It may help doctors better understand health effects during curative therapy and improve care for people your age.
GroningenAges 18–39 - NCT05124288Recruiting
Study immune changes after AML relapse after bone marrow transplant
This study looks at how the immune system changes when acute myeloid leukemia (AML) comes back after a donor stem cell transplant. It may help researchers create more personalized treatment plans and future guidelines for how to care for people in this situation.
Milan, MilanoAges 18 years+ - NCT05294055RecruitingPhase 2
Mecapegfilgrastim to help collect stem cells for transplant
This Phase 2 study tests mecapegfilgrastim with chemotherapy to help your body collect enough peripheral blood stem cells for an autologous transplant (using your own cells). It’s for people with multiple myeloma or certain lymphomas who have already had some response to treatment.
Hefei, AnhuiAges 18–65 - NCT07106723RecruitingPhase 2
Study of stem cell transplant and CD7-CART for T-cell lymphoma
This trial combines your own stem cells (collected before) with a special immune cell therapy (CD7-CART) to treat T-cell lymphoma or leukemia. It may help people with high-risk or hard-to-treat disease.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07110311Recruiting
How pet cats affect nose and gut bacteria in cat allergy patients
This study looks at how living with a pet cat might affect the bacteria in your nose and gut if you have dust mite and cat allergies. It could help us understand if cats actually change your allergy symptoms or the balance of bugs in your body.
Nanjing, JiangsuAges 18–65 - NCT07109128Enrolling by invitation
T1D talks: a support study for type 1 diabetes
This study tests a virtual program where people with type 1 diabetes talk with peers and a coach. It aims to help you manage daily life and feel supported.
Orlando, FloridaAges 12–14 - NCT07106749RecruitingPhase 1
CD180 car T cells for blood cancers that came back
This trial tests a new CAR T cell therapy that targets a protein called CD180 on cancer cells. It is for people with certain types of relapsed or refractory leukemia or lymphoma that has not responded to standard treatments.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07106736RecruitingPhase 2
CAR-T for newly diagnosed multiple myeloma without transplant
This trial is testing a new immunotherapy treatment using CAR-T cells for people with newly diagnosed multiple myeloma who cannot have a stem cell transplant. The treatment aims to target and destroy myeloma cells that have BCMA and GPRC5D proteins on their surface.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07113626Recruiting
HIV testing and PrEP study for young men in Hanoi
This study tests a program to help young men who have sex with men in Hanoi get HIV testing and PrEP (medication to prevent HIV). The goal is to see if a phone-based tool can make it easier to access these services.
HanoiAges 18 years+ - NCT07115342Recruiting
Probiotics and vitamin D for hay fever relief
This study tests whether taking a combination of probiotics (good bacteria) and vitamin D can help reduce hay fever symptoms. It may be a good option if your vitamin D is low and you haven't used probiotics recently.
Tanta, Gharbia GovernorateAges 18–65 - NCT07115017Recruiting
Testing a new PET scan tracer for brain inflammation in MS
This study uses a new radioactive tracer called [18F]-FZTA during a PET scan to see inflammation in the brain. Researchers want to test this tracer in both healthy adults and people with multiple sclerosis (MS) to see if it can help detect MS activity.
St Louis, MissouriAges 18 years+ - NCT07114055RecruitingPhase 2/Phase 3
Ebastine for diarrhea-predominant IBS
This trial tests whether ebastine, an allergy medicine, can help relieve symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D). If you have IBS-D and are at least 18, this study may offer a new option to manage your condition.
DhakaAges 18 years+ - NCT07114939RecruitingPhase 1
A new pet scan for pancreatic neuroendocrine tumors
This study is testing a special type of PET/CT scan using a tracer called FTT to see if it can better find and track pancreatic neuroendocrine tumors that have spread or cannot be removed by surgery. The goal is to improve imaging for people with this type of cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07109323RecruitingPhase 1/Phase 2
Stem cell transplant plus CAR-T for aggressive myeloma
This trial tests combining a stem cell transplant with a special immune cell therapy (BCMA CAR-T) to treat very aggressive multiple myeloma. The goal is to see if this powerful one-two punch can help people whose myeloma is hard to control.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07108998RecruitingPhase 2
Epcoritamab as a follow-up treatment for CLL or SLL
This trial tests the drug epcoritamab as a consolidation therapy for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have had a partial response to a second-generation BTK inhibitor (with or without obinutuzumab) but still have detectable disease. The goal is to see if adding this treatment can lead to a deeper response and better outcomes.
Cincinnati, OhioAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.