Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT05652088Recruiting
Study gut immune tissue in HIV cure efforts
This study looks at how immune tissue in the gut may be involved in curing HIV. You may be asked to have two colonoscopies while on an HIV “cure-related” treatment, so researchers can collect tissue samples to understand what’s happening in your body.
New York, New YorkAges 18–75 - NCT06851767Enrolling by invitationPhase 1/Phase 2
Gene therapy for X-linked severe combined immunodeficiency
This study tests a gene therapy to treat X-linked severe combined immunodeficiency (X-SCID) without a stem cell transplant from a matched sibling. It aims to improve immune function and reduce infections using your own stem cells modified to carry the correct gene.
Bethesda, MarylandAges 3–99 - NCT06856226Recruiting
Drug metabolism study for stem cell transplant patients
This study looks at how your body processes medications after a stem cell transplant from a donor. It aims to find the best way to test your genes to improve future treatments.
Bethesda, MarylandAges 18–120 - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Birmingham, AlabamaAges 40–60 - NCT06856954Recruiting
Skin barrier study for diabetes device users
This study looks at how diabetes devices like insulin pumps or continuous glucose monitors affect the skin barrier. If you have type 1 diabetes and use one of these devices, you may be able to help researchers understand skin health better.
LinköpingAges 2–17 - NCT06846671RecruitingPhase 3
Study of a new drug for CLL or SLL
This trial tests a new investigational drug, BGB-16673, for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have already tried two types of treatments (BTK and BCL2 inhibitors). The goal is to see if this new drug works better than other available treatments chosen by the doctor.
Jonesboro, ArkansasAges 18 years+ - NCT06857214RecruitingPhase 1
GNC-038 antibody study for moderate to severe lupus
This trial tests a new antibody treatment, GNC-038, for people with moderate to severe lupus. It aims to see if it's safe and effective. You must have stable lupus treatment and active B cells in your blood.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06855745RecruitingPhase 2
Testing a new gel for mild to moderate eczema
This study tests a new gel called Zabalafin Hydrogel to see if it helps people with mild to moderate atopic dermatitis (eczema). The gel is applied directly to the skin. If you or your child has eczema on the head, neck, trunk, or limbs, this trial may be an option.
Brookvale, New South WalesAges 2 years+ - NCT06854653RecruitingPhase 2
PTX 100 for relapsed CTCL
This trial tests an experimental drug called PTX 100 for people with cutaneous T-cell lymphoma (CTCL) that has come back after at least two prior treatments. It aims to see if PTX 100 can help shrink tumors or slow the disease.
Duarte, CaliforniaAges 18 years+ - NCT06854718Recruiting
Pain Management Study for People with Dementia
This study tests a new approach to help people with dementia who have chronic pain. It looks at how caregivers can support pain management at home.
Durham, North CarolinaAges 50 years+ - NCT06848738Enrolling by invitation
Faster biopsy for lung cancer or lymphoma near the esophagus
This trial tests a faster way to get a tissue sample from lung cancer or lymphoma tumors that are near the esophagus or stomach. The goal is to start your treatment sooner by using a special ultrasound scope to do a biopsy right away.
NæstvedAges 18 years+ - NCT06855810RecruitingPhase 2/Phase 3
New treatment study for children with T-cell ALL
This study tests a new treatment plan for children and teens newly diagnosed with T-cell acute lymphoblastic leukemia (T-ALL). It aims to see if the approach is safe and works well, and might offer a more tailored therapy for this specific type of leukemia.
Hefei, AnhuiAges 1 month–18 years - NCT06855121Recruiting
Norwegian immunotherapy study for multiple myeloma patients
This study collects information from people with multiple myeloma, plasma cell leukemia, or AL-amyloidosis who are about to start a new type of immunotherapy. It helps doctors understand how these treatments work in real life.
ArendalAges 18 years+ - NCT06854159RecruitingPhase 2
Odronextamab for diffuse large B-cell lymphoma before and after CAR T therapy
This trial tests a drug called odronextamab for people with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. It aims to see if the drug can help before and after a type of immunotherapy called CAR T-cell therapy.
Sacramento, CaliforniaAges 18 years+ - NCT06849713RecruitingPhase 2
New combination treatments for CLL or SLL
This trial tests two different combinations of targeted drugs for people with CLL or SLL who have not had prior treatment for their disease. The goal is to see if these combinations are safe and effective.
Boston, MassachusettsAges 18 years+ - NCT06854848Recruiting
Granulomatosis patient study with biological samples
This study collects medical data and biological samples from people diagnosed with systemic granulomatosis (a condition where tiny clumps of immune cells form in organs) to better understand the disease. It may help develop better treatments in the future.
BordeauxAges 18 years+ - NCT06852950Recruiting
CGM for diabetes management after hospital discharge
This trial tests if using a continuous glucose monitor (CGM) after leaving the hospital helps manage diabetes. You wear a small sensor on your arm that checks your sugar levels all day and sends them to your phone.
Nashville, TennesseeAges 18 years+ - NCT06846463RecruitingPhase 2
Zanubrutinib for DLBCL with specific genetic changes
This trial tests a targeted drug called zanubrutinib combined with standard chemotherapy (R-CHOP) for people with DLBCL who have specific genetic changes in their tumor. The goal is to see if adding this drug can improve outcomes.
Richmond, VirginiaAges 18 years+ - NCT06853314Recruiting
PrEP for women with past legal or child welfare involvement
This trial tests a program to help women who have had contact with the criminal legal system or child protective services get and stay on PrEP (a daily pill that prevents HIV). The study also looks at how to support women who have experienced intimate partner violence or risky drinking.
New York, New YorkAges 18 years+ - NCT06854003RecruitingPhase 2
Study of new drug combo for untreated mantle cell lymphoma
This trial is testing a combination of chemotherapy and targeted drugs for people who have just been diagnosed with mantle cell lymphoma and haven't had any prior treatment (except short-term steroids or local radiation). It aims to see if adding newer targeted therapies can help keep the lymphoma in remission.
Phoenix, ArizonaAges 18 years+ - NCT06847269RecruitingPhase 2
CAR T cell therapy for children and young adults with CD19+ leukemia
This trial tests an immunotherapy called CAR T cells for leukemia that has come back or is hard to treat. It aims to use your own immune cells to fight the cancer.
Memphis, TennesseeAges Up to 21 years - NCT06849960Enrolling by invitation
Reliability and validity of the Two-minute Test for Multiple Sclerosis
This study tests whether a simple two-minute walking test is a reliable way to measure function in people with multiple sclerosis. It aims to help doctors and patients understand the true value of this quick, easy test.
Şehitkamil, GaziantepAges 18–65 - NCT06851715Recruiting
Improving quality of life for teens with asthma
This study tests a program to help teenagers with asthma feel better and have fewer symptoms. It focuses on improving day-to-day quality of life by providing extra support in a respiratory clinic.
Southampton, HampshireAges 12–18 - NCT06851403Enrolling by invitation
Dupilumab for children with asthma in China
This study looks at how well and how safely the medicine Dupilumab works for children whose asthma is not well-controlled with their current inhalers. The goal is to see if it can help reduce asthma attacks and improve daily life.
Guangzhou, GuangdongAges 4–16
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.