Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06528301RecruitingPhase 1
Trial of UB-VV111 with or without rapamycin for B-cell cancers
This trial tests a new therapy called UB-VV111, alone or with rapamycin, in people with certain types of lymphoma or leukemia that have come back or not responded to treatment. The goal is to see if it's safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT06528431RecruitingPhase 4
Personalized tapering of adalimumab for rheumatoid arthritis
This study tests if checking the amount of adalimumab (a biologic drug) in your blood can help doctors safely lower your dose. If you have had rheumatoid arthritis under control for at least 6 months, this trial may help you take less medication while keeping symptoms away.
Caluire-et-CuireAges 18 years+ - NCT06528418Recruiting
Breath test to find lung diseases
This study uses a simple breath test to detect different lung diseases. By analyzing the chemicals in your breath, researchers hope to find a faster, non-invasive way to diagnose lung conditions. It may be an option if you have a known lung disease and have a recent CT scan.
Guangzhou, GuangdongAges 18–100 - NCT06528626Recruiting
Screening tool for HIV and hepatitis C
This study is testing a tool to find people who may be at risk for or already have HIV or hepatitis C. It aims to connect them with care and support.
Madrid, MadridAges 14–65 - NCT06529575Recruiting
How skin color affects pulse oximeter accuracy in children
This study checks if a child's skin color affects how well a pulse oximeter (a small clip on the finger that measures oxygen in the blood) works. It involves children having a heart catheterization, where doctors can directly measure oxygen levels, to see if the pulse oximeter gives the same reading.
New York, New YorkAges 4 weeks–18 years - NCT06529913Recruiting
Metals, pollutants, and risk of allergies
This study looks at whether heavy metals, nanoparticles, and other pollutants in the environment increase the risk of allergic diseases like contact dermatitis. If you have a metal allergy or are a healthy adult, you may help researchers understand how these exposures affect your health.
BolognaAges 18 years+ - NCT06530511RecruitingPhase 2
PRO trial for elderly, frail patients with a type of lymphoma
This trial tests a combination of three drugs (Polatuzumab, Rituximab, and Orelabrutinib) for elderly patients who are frail or over 80 with a specific type of untreated diffuse large B-cell lymphoma (non-GCB DLBCL). The goal is to see if this drug combo is safe and effective for those who may not tolerate standard chemotherapy.
Nantong, JiangsuAges 60 years+ - NCT06530550RecruitingPhase 2
PI3K inhibitor for relapsed T/NK-cell lymphoma
This trial tests a targeted therapy called a PI3K inhibitor for people whose T-cell or NK-cell lymphoma has returned or not improved after other treatments. It aims to see if the drug can shrink or control the lymphoma.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06530576RecruitingPhase 2
Thalidomide for symptomatic large granular lymphocytic leukemia
This trial tests the drug thalidomide for people with symptomatic large granular lymphocytic leukemia (LGLL), a rare blood cancer. It aims to see if thalidomide can help control the disease and improve symptoms like low blood counts or an enlarged spleen.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06531018RecruitingPhase 1/Phase 2
Eltrombopag for newly diagnosed ITP patients
This trial tests if eltrombopag, a medication that helps the body make more platelets, works as the first treatment for people newly diagnosed with immune thrombocytopenia (ITP, a condition where the immune system destroys platelets, causing bleeding problems). It may help raise your platelet count and reduce bleeding risk.
DhakaAges 18–70 - NCT06531772Recruiting
Study of TB and HIV co-infection outcomes
This study looks at the health of people who have both tuberculosis (TB) and HIV. It helps doctors understand how the two infections affect each other and what treatments work best.
AsyutAges Any age - NCT06532526Recruiting
Tooth sensitivity treatment during teeth whitening
This study tests whether a special desensitizing gel can reduce tooth sensitivity caused by professional teeth whitening. If you are a smoker between 18 and 30 with dark anterior teeth wanting whiter teeth, this may help you experience less discomfort.
IrbidAges 18–35 - NCT06532461Recruiting
Comparing 3 vs 7 day insulin pump wear in teens with type 1 diabetes
This study tests if wearing an insulin pump set for 7 days is as safe and effective as changing it every 3 days. It is for children and teens with type 1 diabetes who already use the Medtronic 780G system.
Herlev, CapitalAges 7–18 - NCT06532643RecruitingEarly Phase 1
CAR-T cells targeting CD20 and CD30 for relapsed lymphoma
This trial tests a new CAR-T cell therapy that targets two proteins (CD20 and CD30) on lymphoma cells. It is for people whose lymphoma has come back or not responded to other treatments, including previous stem cell transplants. The goal is to see if this treatment is safe and helps shrink or control the lymphoma.
Hefei, AnhuiAges 14–70 - NCT06533462Recruiting
Slow multi-food allergy treatment in young children
This trial tests a slow, multi-food oral immunotherapy (giving small amounts of several foods) in young children with food allergies. It aims to see if this treatment can help children safely eat more foods without allergic reactions.
StockholmAges 6 months–3 years - NCT06533423Recruiting
Self-management help for new arthritis patients
This trial tests a self-management program for people recently diagnosed with certain types of arthritis. It aims to help you better manage your condition through education and support.
Glostrup MunicipalityAges 18–120 - NCT06534060RecruitingPhase 2
Testing MB-105 for CD5 positive T-cell lymphoma
This trial tests a new treatment called MB-105 for people with a type of T-cell lymphoma that has come back or not responded to other treatments. MB-105 is designed to target and attack cancer cells that have a specific marker called CD5 on their surface.
San Diego, CaliforniaAges 18 years+ - NCT06534021RecruitingPhase 1
Study of IASO-782 for autoimmune blood disorders
This trial tests a new drug called IASO-782 for people with immune thrombocytopenia (ITP) or warm autoimmune hemolytic anemia (wAIHA) who haven't gotten better with standard treatments. The goal is to see if the drug can help control the immune system and improve blood counts.
Wuhan, HubeiAges 18–65 - NCT06534463Recruiting
MZL patient registry study
This study is a registry that collects information on Chinese patients with marginal zone lymphoma. It helps doctors learn more about how MZL behaves and how it is treated.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT06534437RecruitingPhase 2
Study of MEN1703 for aggressive B-cell lymphoma
This trial tests a new drug called MEN1703, alone or with another drug (glofitamab), for people with aggressive B-cell non-Hodgkin lymphoma that has come back or not responded after at least two prior treatments. The goal is to see if it can help shrink tumors.
Le MansAges 18 years+ - NCT06534762RecruitingPhase 2
Miraberon for advanced solid tumors (first treatment)
This study tests a drug called Miraberon for people with advanced solid tumors that have not yet been treated with chemotherapy or other cancer drugs. The goal is to see if Miraberon can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18–65 - NCT06535087Recruiting
How airway allergies affect children and parents' quality of life
This study looks at how airway allergies (like asthma and hay fever) affect the daily life of children and their parents. By filling out a questionnaire, you can help researchers understand these challenges and find better ways to support families.
Shanghai, Shanghai MunicipalityAges 5–16 - NCT06536075Recruiting
Salivary gland function in Sjogren's syndrome
This study looks at how well your salivary glands work and if there is a connection with a special scan called sialoscintigraphy. It may help people with or without dry mouth symptoms and a Sjogren's diagnosis.
TaipeiAges 20–70 - NCT06536413RecruitingPhase 1/Phase 2
ATRA and Carfilzomib for multiple myeloma
This trial tests if combining the drug ATRA with carfilzomib can help people with multiple myeloma whose cancer has come back or stopped responding to at least three prior treatments, including carfilzomib. The goal is to see if this new combination works better than carfilzomib alone.
Houston, TexasAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.