Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06851715Recruiting
Improving quality of life for teens with asthma
This study tests a program to help teenagers with asthma feel better and have fewer symptoms. It focuses on improving day-to-day quality of life by providing extra support in a respiratory clinic.
Southampton, HampshireAges 12–18 - NCT04053439Recruiting
Testing blood-clone risk to prevent chemotherapy complications
This study looks at a specific genetic/production change in blood-forming cells (“clonal hematopoiesis”) to understand who is more likely to have complications from lymphoma chemotherapy. It may help doctors predict risk and possibly reduce harmful side effects.
Toronto, OntarioAges 60 years+ - NCT05203640Recruiting
Strength exercise study for post-menopausal type 1 diabetes
This study checks whether a resistance (strength) exercise program changes blood sugar levels in post-menopausal women with type 1 diabetes. You may be asked to do supervised lab-based exercise sessions near the University of Alberta.
Edmonton, AlbertaAges 45–75 - NCT06618027Recruiting
Mindfulness program for teens with type 1 diabetes and mood concerns
This trial tests a mindfulness program designed to help teens with type 1 diabetes who are also dealing with feelings of depression or anxiety. The goal is to see if this program can improve their mood and overall well-being.
Aurora, ColoradoAges 13–17 - NCT06753214Recruiting
Telemedicine training for caregivers to improve child asthma control
This trial tests if teaching caregivers about asthma care through telemedicine can help children with uncontrolled asthma feel better. It is designed for children whose asthma is not well-controlled and who are already being treated at a hospital clinic.
Can ThoAges 4–16 - NCT06729242Recruiting
How menstrual cycle phases affect exercise and blood sugar in type 1 diabetes
This study looks at how the menstrual cycle changes the way your body responds to aerobic exercise or high-intensity interval training (HIIT) when you have type 1 diabetes. It may help you understand the best time to exercise for better blood sugar control.
Valencia, Select OneAges 18–45 - NCT06846281RecruitingPhase 3
Remibrutinib for relapsing multiple sclerosis after switching from Ocrevus
This study tests a new oral medication called remibrutinib for people with relapsing multiple sclerosis who are currently on Ocrevus. Participants will switch from Ocrevus to remibrutinib to see if it is safe and effective.
Scottsdale, ArizonaAges 40–70 - NCT06838143Recruiting
Ilaris real-world study for periodic fevers and sJIA
This study watches how people with certain periodic fever syndromes or a severe type of childhood arthritis (sJIA) do on the medicine Ilaris during their regular doctor visits. It collects information to see how well the medicine works in everyday care.
SeoulAges 2–100 - NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06838832RecruitingPhase 1/Phase 2
New CAR-T cell therapy for relapsed B-cell lymphoma
This trial tests a new treatment made from your own immune cells (gamma-delta T cells) that are engineered to find and kill CD19-positive lymphoma cells. It is for people with B-cell non-Hodgkin lymphoma whose cancer has not responded to or has returned after at least two standard treatments.
Beijing, Beijing MunicipalityAges 18–75 - NCT06841562Recruiting
Home Exercise and Anti-inflammatory Program for Early RA
This study tests if a home-based exercise program, combined with anti-inflammatory strategies, can help people newly diagnosed with rheumatoid arthritis manage their symptoms and improve health. It's a remote program, so you can participate from home.
Durham, North CarolinaAges 18 years+ - NCT06839053RecruitingPhase 2
Study of sonrotoclax, rituximab, and zanubrutinib for CLL, SLL, and MCL
This trial tests a combination of three drugs (sonrotoclax, rituximab, and zanubrutinib) for people with chronic lymphocytic leukemia, small lymphocytic lymphoma, or mantle cell lymphoma. The goal is to see if the combination works better than current treatments.
Seattle, WashingtonAges 18 years+ - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06839976RecruitingPhase 1/Phase 2
CART19 cell therapy for lupus
This trial tests a treatment called CART19, where your own immune cells are modified in a lab to target and destroy faulty B cells that cause lupus inflammation. It's for young people with active lupus that hasn't improved with standard treatments.
Philadelphia, PennsylvaniaAges 10–29 - NCT06844110Recruiting
New PET scan for cancer using CD73 probe
This trial tests a new PET imaging agent that targets CD73, a protein found on many cancer cells. It may help doctors see tumors more clearly without chemotherapy or radiation before the scan.
Dongcheng, Beijing MunicipalityAges 18–70 - NCT06838962RecruitingPhase 2
Study of anti-CD38 antibody for children with chronic ITP
This trial tests a new antibody treatment (anti-CD38) for children ages 6 to 18 who have had low platelets for at least 3 months and did not improve with steroids. The goal is to see if this treatment can safely raise platelet counts.
Tianjin, Tianjin MunicipalityAges 6–18 - NCT05200715Recruiting
Registry study for inherited and inflammatory eye and joint diseases
This study is a registry, meaning it collects your medical information to better understand several inflammatory (auto-inflammatory) conditions. It may help doctors and researchers improve diagnosis and future treatments for people with these disorders.
AlgiersAges Any age - NCT04331522Recruiting
Food or antibiotic allergy testing with controlled allergen exposure
This trial studies people who may have an allergy to certain foods or antibiotics by giving small, controlled exposures to help confirm what’s causing reactions. If your symptoms match, the results could help your doctors guide safer food or medication choices.
Odense, Odense CAges birth–18 years - NCT06312046Recruiting
Thinking and Movement in MS: A Balance Study
This study tests how thinking and movement interact in people with MS who have some balance problems. It aims to find ways to improve daily function.
Stockholm, Stockholm CountyAges 18–65 - NCT06421415Recruiting
Long-term effects of allergy shots in children
This study looks at how well allergy shots or drops work over the long term in children who received this treatment at Odense University Hospital. It aims to understand if the benefits last for years after treatment ends.
Odense, Odense CAges 4–18 - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06831331Enrolling by invitation
Diet and nutrition for newly diagnosed rheumatoid arthritis
This study tests whether a special diet can help manage symptoms of newly diagnosed rheumatoid arthritis. It aims to see if eating certain foods can reduce inflammation and improve your overall health.
GothenburgAges 18–85 - NCT06829771RecruitingPhase 1/Phase 2
A new drug combined with standard chemo for large B-cell lymphoma
This trial is testing a new drug called TQB2825 given alongside standard chemotherapy (R-CHOP or GemOx) for people with diffuse large B-cell lymphoma (DLBCL) or a related type called grade 3b follicular lymphoma. The goal is to see if adding this new drug is safe and works better than standard treatment alone.
Bengbu, AnhuiAges 18–80
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.