Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06756490RecruitingPhase 1
Study of HY-2003 for double chin reduction
This study tests a new medicine called HY-2003 to reduce extra fat under the chin (double chin). It is for adults who have moderate to severe submental fat and want to see if injections can help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06751238RecruitingPhase 1
Secukinumab for children with psoriatic arthritis
This study tests a drug called secukinumab (given through an IV) in children with juvenile psoriatic arthritis. The goal is to see how well it works and if it's safe over time, for up to 6 years.
Loma Linda, CaliforniaAges 2–17 - NCT06752356RecruitingPhase 3
A study of a new IVIG treatment for CIDP
This study tests a new intravenous immunoglobulin (IVIG) treatment called KIg10 (QIVIGY) for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It aims to see if this treatment can help manage symptoms and maintain stability.
Stamford, ConnecticutAges 18 years+ - NCT06760208Recruiting
Learning about Prevenar 20 in the real world in Korea
This study is for people who are already getting the Prevenar 20 vaccine (a shot that protects against pneumonia and other infections) as part of their regular care. The researchers want to see how well it works in the real world, so it's a simple way to help improve vaccines for everyone.
SeoulAges 1 month+ - NCT06443346Recruiting
Registry for people with eosinophilic esophagitis
This is a registry (like a medical diary) for people with EoE who are getting regular treatment. It helps doctors track how EoE affects people over time, so they can improve care for everyone.
Milan, LombardyAges Any age - NCT06739811Recruiting
Implantable insulin pump for hard-to-control type 1 diabetes
This trial tests a new implantable insulin pump for adults with type 1 diabetes that is difficult to manage with shots or external pumps. The pump is placed under the skin and delivers insulin automatically, aiming to reduce dangerous highs and lows in blood sugar.
Bordeaux, FranceAges 18 years+ - NCT06742996RecruitingPhase 3
Sonrotoclax plus zanubrutinib for relapsed mantle cell lymphoma
This trial tests a new combination of two targeted therapies for people with mantle cell lymphoma that has come back or hasn't responded to prior treatment. It aims to see if adding sonrotoclax to zanubrutinib works better than zanubrutinib alone.
Birmingham, AlabamaAges 18 years+ - NCT06748001RecruitingPhase 4
Avapritinib follow-up study for previous trial participants
This study provides continued access to avapritinib for people who have already been in a Blueprint Medicines trial and are still benefiting from the drug. It allows you to keep receiving treatment while staying monitored for safety.
EdegemAges Any age - NCT06744569Enrolling by invitationPhase 1
Testing a new ointment for atopic dermatitis in healthy adults and patients
This trial tests a new ointment called CU-10101. It will first be tested in healthy volunteers to check safety, and then in people with atopic dermatitis (eczema) to see how well it works for mild to moderate symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Avondale, ArizonaAges 18 years+ - NCT06747351RecruitingPhase 3
Comparing two immune globulin treatments for CIDP
This study tests if TAK-881 is as safe and effective as HYQVIA for adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). You may join if you have been stable on immune globulin therapy and have certain disability levels.
Scottsdale, ArizonaAges 18 years+ - NCT05264025RecruitingPhase 1/Phase 2
Fexofenadine for active rheumatoid arthritis
This Phase 1/2 study tests whether fexofenadine (an allergy medicine) can improve symptoms and inflammation in people with active rheumatoid arthritis. Participants may be assigned to different treatment groups, and the study looks at safety and early signs of benefit.
Banī SuwayfAges 18–60 - NCT05659732RecruitingPhase 1
Testing a new drug for advanced blood cancers
This early-phase study tests PEP07, a drug that blocks a cancer signal pathway (Checkpoint Kinase 1). It aims to see how well it works and how safely it can be given to people with certain advanced relapsed or refractory blood cancers.
Clayton, VictoriaAges 18 years+ - NCT06748118Recruiting
Reminders to help you take your medicines regularly
This study tests if simple, repeated reminders from your healthcare team can help you stick to your daily medicines for a chronic condition. You might benefit by getting more support during your hospital visits.
Angers, FranceAges 18 years+ - NCT06741618Recruiting
HIV prevention study for young men
This study tests a mobile app to help young men who have sex with men stay HIV-negative. It focuses on people who have had condomless anal sex recently and are not using PrEP.
New York, New YorkAges 16–25 - NCT06748963Recruiting
Fasted exercise training for type 1 diabetes
This study tests if exercising before breakfast (while fasting) helps improve blood sugar control and heart health in people with type 1 diabetes. You'll continue using your insulin pump and glucose monitor, and attend supervised exercise sessions and MRI scans to measure changes in your body.
Edmonton, AlbertaAges 18–55 - NCT06746077Enrolling by invitation
Lung disease study in children: new ways to understand infections
This study explores how the immune system and lung microbes affect children with lung disease. It uses extra fluid collected during a standard lung exam to look for new treatment targets.
Aarhus NAges birth–17 years - NCT06747910Recruiting
Remote test for nerve problems after childhood cancer
This study tests if a remote, at-home approach can identify problems with the autonomic nervous system (the part that controls heart rate, blood pressure, and digestion) in adult survivors of childhood leukemia or lymphoma. If you join, you will complete a set of simple tasks (the Ewing battery) from home to see how your body responds.
Memphis, TennesseeAges 18 years+ - NCT06741631Recruiting
Mobile app to help young men reduce HIV risk
This trial tests a mobile app designed to help young men who have sex with men (and non-binary people assigned male at birth) reduce their risk of HIV. It's for people who are HIV-negative or don't know their status, and who have had anal sex with a partner with a penis in the last year.
Chicago, IllinoisAges 16–29 - NCT06747156RecruitingEarly Phase 1
mRNA medicine for refractory autoimmune diseases
This trial tests a new type of medicine (ABO2203) that trains your immune system to attack the cells causing your autoimmune disease. It's for people who haven't gotten better with standard treatments.
Wuhan, HubeiAges 18 years+ - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT06556199RecruitingPhase 1/Phase 2
Study of selinexor combo for returning brain lymphoma
This trial tests a new combination of drugs (selinexor, temozolomide, and an immunotherapy) for people whose primary central nervous system lymphoma has come back or stopped responding to previous treatment. The goal is to see if this combination can help shrink or control the lymphoma.
Hanzhou, ZhejiangAges 18–75 - NCT04711200RecruitingPhase 1/Phase 2
Study of special stem cells for severe skin peeling (SJS-TEN)
This early-phase trial tests stem-cell treatment to help people with severe skin reactions called SJS-TEN. It may reduce ongoing skin damage and help recovery when treatment is started soon after symptoms begin.
CréteilAges 18–75 - NCT05660473RecruitingPhase 2
Study of venetoclax plus chemotherapy for Ph-negative ALL
This Phase 2 trial tests whether adding venetoclax to a chemotherapy plan works better for Philadelphia chromosome–negative acute lymphoblastic leukemia (ALL). It may help people achieve deeper remission by targeting leukemia cells in a different way than chemotherapy alone.
TianjinAges 14–60
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.