Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06616389RecruitingPhase 1/Phase 2
OsteoDex for multiple myeloma in previously treated patients
This study tests a new drug called OsteoDex (ODX) for people with multiple myeloma whose cancer has continued to worsen after trying 1 to 5 earlier treatments. The goal is to see if OsteoDex can help control the disease.
StockholmAges 18 years+ - NCT06617741Recruiting
Global Registry for Myasthenia Gravis Patients
This trial is a global registry for people with myasthenia gravis (MG). It collects information to help researchers better understand MG and improve care.
Westborough, MassachusettsAges 18 years+ - NCT06618027Recruiting
Mindfulness program for teens with type 1 diabetes and mood concerns
This trial tests a mindfulness program designed to help teens with type 1 diabetes who are also dealing with feelings of depression or anxiety. The goal is to see if this program can improve their mood and overall well-being.
Aurora, ColoradoAges 13–17 - NCT06618573RecruitingPhase 2/Phase 3
Can isoniazid prevent TB in lupus patients?
This study tests if taking the TB prevention medicine isoniazid is safe for people with lupus (SLE). It may help protect you from getting tuberculosis while managing your lupus.
Bandung, West JavaAges 18–55 - NCT06618963RecruitingPhase 4
Omalizumab for food allergy skin effects
This trial tests if omalizumab (Xolair) can improve skin reactions in people with food allergies. It may help reduce allergic symptoms triggered by foods like peanut, egg, or milk.
Denver, ColoradoAges 1–55 - NCT06619288Recruiting
HIV treatment study comparing B/F/TAF to older drugs
This study tests a newer HIV medication, B/F/TAF, as a first-line treatment. It compares B/F/TAF with older combinations (TDF+3TC+EFV or DTG/3TC) to see how well it works for people who have never taken HIV meds.
Nantong, JiangsuAges 18 years+ - NCT06619561RecruitingPhase 2
Testing vimseltinib for chronic graft versus host disease
This trial tests a new drug called vimseltinib for people with active chronic graft versus host disease (cGVHD) that hasn't gotten better after at least two prior treatments. The goal is to see if vimseltinib can help control the condition.
Duarte, CaliforniaAges 18 years+ - NCT06620809RecruitingPhase 1
Safety and efficacy of NouvSoma001 for NMOSD
This trial tests a new treatment called NouvSoma001 for neuromyelitis optica spectrum disorder (NMOSD), a condition where the immune system attacks the optic nerves and spinal cord. It looks at whether the drug is safe and helps people who have had a recent attack with severe pain, trouble walking, or bladder/bowel problems.
Wuhan, HubeiAges 18–65 - NCT06621056Recruiting
Risk factors and outlook for frequent asthma flare-ups
This study looks at people with asthma to understand what raises the risk of having frequent asthma attacks and how these attacks affect long-term health. The goal is to find ways to better predict and help manage these flare-ups.
Beijing, Beijing MunicipalityAges 18–80 - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT06623799Recruiting
Allergic rhinitis, help-seeking, and mental health study
This study looks at how people with allergic rhinitis (hay fever) seek help and how that relates to their mental health. Researchers hope to learn more about the connection between allergies, anxiety, and depression over time.
West Palm Beach, FloridaAges 4–100 - NCT06624046Recruiting
Sleep and glucose study for type 1 diabetes
This study looks at how sleep affects blood sugar and heart health in people with type 1 diabetes. If you have irregular sleep and want to improve it, researchers will test a wearable device and sleep coaching.
Chicago, IllinoisAges 18–50 - NCT06624696RecruitingPhase 4
Inhaled penehyclidine to prevent breathing problems in children having eye surgery
This study tests whether giving a medication called penehyclidine (given as a mist inhaled before surgery) can help prevent breathing problems in children aged 3–7 who are having eye surgery and are at risk for such problems. The medicine is compared to a placebo (a mist with no active drug).
Guangzhou, GuangdongAges 3–7 - NCT06624735Recruiting
Behavior changes in children with asthma
This study looks at how children with asthma behave and what factors might affect their condition. It aims to help improve care for kids with asthma.
SohagAges 4–12 - NCT06625203Recruiting
Building a large cancer data collection from patients worldwide
This study is building a large collection of cancer data (like medical records, images, and genetic information) from many patients. It aims to learn more about different cancers and may lead to better treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06625216Recruiting
Severe asthma registry in Italy
This study collects information from people with severe asthma across Italy to better understand the condition and improve treatment. By joining, you help researchers learn what works best for people like you.
Rozzano, MilanoAges 13 years+ - NCT06625671RecruitingPhase 1/Phase 2
DB-2304 antibody injection for lupus skin disease (SLE/CLE)
This trial tests an experimental antibody injection (DB-2304) to see if it can improve lupus skin rashes and other lupus symptoms. It is for people with active lupus skin disease who have already tried standard treatments.
La Palma, CaliforniaAges 18–70 - NCT06626672Recruiting
Digital Health Program for Kids with Heart Defects
This study uses digital tools to promote healthy habits in children (ages 8–14) with congenital heart disease. It aims to support both the child and their family in staying active and well.
MünchenAges 8–14 - NCT06626737RecruitingPhase 2
Testing dapagliflozin to prevent GVHD after stem cell transplant
This trial tests whether adding dapagliflozin (a diabetes medication) to standard care can help prevent graft-versus-host disease after a stem cell transplant for blood cancer. It may be an option for adults who are about to receive a transplant from a half-matched or unrelated donor.
Suzhou, JiangsuAges 18–65 - NCT06626893Recruiting
Leukemia study using advanced tests to find targeted treatment
This study uses advanced tests (genetics and other 'omics' methods) to better understand your leukemia and find a treatment that targets its specific features. It may help if standard treatments haven't worked or stopped working.
Meldola, Forlì-CesenaAges 18 years+ - NCT06626919RecruitingPhase 1
A cell therapy trial for generalized myasthenia gravis
This trial tests a new cell therapy called anitocabtagene autoleucel (anito-cel) for people with generalized myasthenia gravis (gMG) that is not well controlled with current treatments. The goal is to see if it can reduce symptoms and improve quality of life.
Los Angeles, CaliforniaAges 18 years+ - NCT06627335Recruiting
Eczema creams and pregnancy outcomes study
This study looks at women who used a topical eczema cream called ruxolitinib (Opzelura) or steroid creams during pregnancy. The goal is to compare pregnancy outcomes and baby health up to one year after birth.
Morrisville, North CarolinaAges 14 years+ - NCT06627309Recruiting
Rapid blood protein response and remission in AL amyloidosis
This trial is for people with AL amyloidosis who are being treated with daratumumab, bortezomib, and dexamethasone. It looks at how quickly a certain blood protein (called dFLC) drops after treatment starts and whether that predicts a complete remission.
Beijing, Beijing MunicipalityAges 18–99 - NCT06627504Recruiting
Sleep study for teens with type 1 diabetes
This study tests whether getting more sleep helps improve metabolic health in teens with type 1 diabetes who are not getting enough sleep. If you are between 14 and 19, use an insulin pump, and typically sleep 7 hours or less on school nights, you may be eligible.
Aurora, ColoradoAges 14–19
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.