Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06845592Recruiting
Stronger radiation and cell therapy before stem cell transplant for high-risk leukemia
This trial tests a special transplant approach for people with high-risk acute leukemia. It uses a stronger dose of radiation before transplant, followed by an infusion of immune cells (regulatory and conventional T cells) to help the transplant work better and fight the leukemia.
Perugia, PGAges 18–65 - NCT06845722Recruiting
Balance and cognitive training for multiple sclerosis
This trial tests whether combining balance exercises with brain-training activities can help improve walking and thinking in people with multiple sclerosis. It is for people aged 40–55 who have mild cognitive problems and balance issues.
LahoreAges 40–55 - NCT06846385RecruitingPhase 2/Phase 3
Testing a new shot for severe seasonal hay fever
This study tests a new injection called MG-K10 for people with moderate-to-severe seasonal hay fever that isn't well controlled by standard treatments like nasal sprays or antihistamines. The goal is to see if it can reduce your allergy symptoms over the pollen season.
Beijing, Beijing MunicipalityAges 18–75 - NCT06846489RecruitingPhase 2
Acalabrutinib plus rituximab for untreated mantle cell lymphoma
This trial tests a combination of two targeted drugs (acalabrutinib and rituximab) for people with mantle cell lymphoma who have not had treatment before. It is designed for older patients or younger patients with a less aggressive form of the disease.
Guangzhou, GuangdongAges 18 years+ - NCT06846463RecruitingPhase 2
Zanubrutinib for DLBCL with specific genetic changes
This trial tests a targeted drug called zanubrutinib combined with standard chemotherapy (R-CHOP) for people with DLBCL who have specific genetic changes in their tumor. The goal is to see if adding this drug can improve outcomes.
Richmond, VirginiaAges 18 years+ - NCT06846905Recruiting
Cost and effects of raising the dose of myeloma drugs at home vs. hospital
This study compares whether raising the dose of your current bispecific antibody is more cost-effective when done as an outpatient (day hospital) or as an inpatient. It aims to find the best way to manage your treatment safely.
ToulouseAges 18 years+ - NCT06847269RecruitingPhase 2
CAR T cell therapy for children and young adults with CD19+ leukemia
This trial tests an immunotherapy called CAR T cells for leukemia that has come back or is hard to treat. It aims to use your own immune cells to fight the cancer.
Memphis, TennesseeAges Up to 21 years - NCT06848608Recruiting
Yoga vs. physical therapy for sarcoidosis fatigue
This study compares the benefits of yoga versus standard physical therapy for people with sarcoidosis who have lung involvement and fatigue. It aims to find which approach better helps manage symptoms and improve daily life.
Istanbul, MaltepeAges 18–75 - NCT06849622Recruiting
Blood spot test for type 1 diabetes and celiac disease
This study tests a new way to check for type 1 diabetes and celiac disease using a tiny drop of blood from a finger prick, instead of a regular blood draw. The goal is to make diagnosis easier and less scary for children.
Florence, ItalyAges 2–13 - NCT06849882Recruiting
Balance test study for people with multiple sclerosis
This study will test whether a simple balance test (the Dubousset Functional Test) is reliable and accurate for people with MS. If you have mild disability and can stand without help, you may be able to join.
Kayseri, KayseriAges 18–65 - NCT06852638RecruitingPhase 2
PET imaging for kidney cancer, lymphoma, and NPC
This study tests a new way to detect tumors by using a special injection that makes cancer cells visible on a PET scan. It may help people with renal cancer (especially clear cell type), lymphoma, or nasopharyngeal cancer.
ShanghaiAges 18–80 - NCT06850285Recruiting
CD30 CAR-T for relapsed or refractory CD30+ lymphoma
This trial tests a new type of immunotherapy called CD30 CAR-T cells for people with CD30-positive lymphoma that has come back or hasn't responded to other treatments. The treatment uses your own immune cells that are specially trained to find and kill lymphoma cells carrying the CD30 marker.
Taiyuan, ShangxiAges 15–80 - NCT06850311RecruitingPhase 2/Phase 3
Herbal ointment for mild to severe eczema
This trial tests whether a special herbal ointment can help treat atopic dermatitis (eczema). It is for adults with mild, moderate, or severe eczema covering less than 10% of their body surface. The ointment is applied directly to the skin, and participants will also use a gentle, fragrance-free moisturizer.
New Taipei CityAges 18–65 - NCT06851715Recruiting
Improving quality of life for teens with asthma
This study tests a program to help teenagers with asthma feel better and have fewer symptoms. It focuses on improving day-to-day quality of life by providing extra support in a respiratory clinic.
Southampton, HampshireAges 12–18 - NCT06852911Recruiting
New FeNO device for asthma diagnosis
This study tests a new device that measures a lung marker called FeNO (fractional exhaled nitric oxide) to help diagnose asthma. It may be an option for adults with asthma who have not changed their medication recently and have no recent infections.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06852950Recruiting
CGM for diabetes management after hospital discharge
This trial tests if using a continuous glucose monitor (CGM) after leaving the hospital helps manage diabetes. You wear a small sensor on your arm that checks your sugar levels all day and sends them to your phone.
Nashville, TennesseeAges 18 years+ - NCT06853314Recruiting
PrEP for women with past legal or child welfare involvement
This trial tests a program to help women who have had contact with the criminal legal system or child protective services get and stay on PrEP (a daily pill that prevents HIV). The study also looks at how to support women who have experienced intimate partner violence or risky drinking.
New York, New YorkAges 18 years+ - NCT06853444RecruitingPhase 1/Phase 2
ESG206 for adults with hard-to-treat ITP
This trial tests a new drug called ESG206 for adults with immune thrombocytopenia (ITP) whose platelet counts remain very low despite previous treatments like steroids or IVIG. The goal is to see if ESG206 can safely help raise platelet levels and reduce bleeding risk.
Jinan, ShandongAges 18 years+ - NCT06853834Recruiting
Comparing two biopsy methods for suspected sarcoidosis
This trial compares two ways of taking a lung tissue sample (cryo biopsy vs forceps biopsy) in people who may have sarcoidosis. The goal is to see which method is better at diagnosing the condition.
Lucknow, Uttar PradeshAges 18 years+ - NCT06854003RecruitingPhase 2
Study of new drug combo for untreated mantle cell lymphoma
This trial is testing a combination of chemotherapy and targeted drugs for people who have just been diagnosed with mantle cell lymphoma and haven't had any prior treatment (except short-term steroids or local radiation). It aims to see if adding newer targeted therapies can help keep the lymphoma in remission.
Phoenix, ArizonaAges 18 years+ - NCT06854159RecruitingPhase 2
Odronextamab for diffuse large B-cell lymphoma before and after CAR T therapy
This trial tests a drug called odronextamab for people with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. It aims to see if the drug can help before and after a type of immunotherapy called CAR T-cell therapy.
Sacramento, CaliforniaAges 18 years+ - NCT06854445RecruitingPhase 2
TQB2825 plus chemo for relapsed/refractory DLBCL
This trial tests a new drug called TQB2825 combined with chemotherapy for people with diffuse large B-cell lymphoma (DLBCL) that has come back or not responded to at least one prior treatment. It aims to see if this combination can help when other treatments haven't worked and stem cell transplant is not an option.
Wuhu, AnhuiAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.