Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,050 recruiting studies in this area right now.
By phase
- Not applicable2,999
- Phase 21,056
- Phase 1792
- Phase 1/Phase 2437
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes130
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland199
- Alabama178
- Florida149
- Arizona148
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,050 total
- NCT00825929Recruiting
Drug levels in HIV treatment during pregnancy
This study measures how HIV medicines move through your body during pregnancy by collecting blood samples after you take your regular treatment. It may help improve understanding of dosing and drug levels in pregnant people living with HIV.
BrusselsAges 18 years+ - NCT06179524RecruitingPhase 2
CAR-T-19 for CD19-positive B-ALL in children and young adults
This trial tests a new type of immunotherapy called CAR-T-19 for children and young adults up to age 25 whose B-ALL has returned or is not responding to standard treatments. The CAR-T cells are engineered to find and destroy leukemia cells that have the CD19 protein.
TianjinAges Up to 25 years - NCT05634967Recruiting
Kesimpta pregnancy registry for pregnant people with MS
This registry collects information about pregnancy outcomes in people with multiple sclerosis (MS) who have taken Kesimpta (ofatumumab) during pregnancy or shortly before it. It may help doctors better understand safety and developmental outcomes for babies.
La Jolla, CaliforniaAges 18–100 - NCT05697159Recruiting
7-tesla brain MRI to study how filgotinib eases RA pain
This trial uses a very high-strength brain MRI to understand how the RA medicine filgotinib may reduce pain. If you have active rheumatoid arthritis and can safely complete the scan, the study may help researchers better target pain relief in RA.
GlasgowAges 18–74 - NCT06774677Recruiting
Studying cell communication in hairy cell leukemia for better care
This study looks at how cells talk to each other in hairy cell leukemia, a rare blood cancer. It aims to find ways to improve patient care. Participants may be asked to give blood or tissue samples for research.
Palermo, PAAges 18 years+ - NCT06774339Recruiting
Biomarkers in transplant patients over time
This study is following people who have had a liver, kidney, heart, or lung transplant. It will look for markers in your blood that might help predict how you do in the short and long term after transplant.
BolognaAges 18 years+ - NCT06772922Recruiting
Pulmonary and heart rehab program testing combined exercise
This trial studies a combined lung and heart rehabilitation program for people with lung diseases (like COPD, asthma, or fibrosis) or heart conditions (like heart attack, bypass surgery, or heart failure). The goal is to see if a special exercise program can improve your health and quality of life.
Campinas, São PauloAges 18 years+ - NCT06774326Recruiting
Spectral CT to check for heart damage from lymphoma treatment
This study uses a special type of CT scan called spectral CT to see if chemotherapy drugs called anthracyclines can cause heart damage in people with certain lymphomas. The goal is to catch any heart problems early by imaging the heart before, during, and after treatment.
BolognaAges 18 years+ - NCT06773546Recruiting
Immune system disorders study for children and adults
This study looks at people with known or suspected inborn errors of immunity (problems with the immune system that you are born with). The goal is to improve how these conditions are diagnosed and managed. If you have immune system issues that started before age 50, you may be able to join.
Bologna, BolgonaAges Up to 50 years - NCT07483346RecruitingPhase 1
Testing IASO-782 for systemic lupus erythematosus
This trial tests a new medicine called IASO-782 for people with systemic lupus erythematosus (SLE). It aims to see if the drug can help control lupus symptoms when added to standard treatments.
Hangzhou, ZhejiangAges 18–75 - NCT07488065RecruitingPhase 1
New drug for moderate to severe eczema
This trial tests a new injectable drug called SKB575 for people with moderate to severe atopic dermatitis (eczema). It aims to see how safe and effective the drug is, especially for those who haven't had success with strong creams or pills.
ShanghaiAges 18–70 - NCT07486401Recruiting
Blood eosinophil-guided asthma care in primary care
This trial tests whether using a blood test (eosinophil count) to guide asthma treatment works better than usual care for people with mild to moderate asthma. If you have asthma and are on step 1-3 treatment, this study could help improve your symptom control.
SingaporeAges 21–65 - NCT07485647RecruitingPhase 2
Finding the best dose of daratumumab for multiple myeloma patients after transplant
This trial tests different dosing schedules of daratumumab to find a more cost-effective option for patients with multiple myeloma who have already had a stem cell transplant and achieved at least a partial response. It aims to see if a lower dose can work just as well.
Nashville, TennesseeAges 18–70 - NCT07484243Recruiting
Chinese and Western medicine for rheumatoid arthritis
This study combines traditional Chinese medicine with Western medicine to treat rheumatoid arthritis. It aims to see how well this approach works for people with hard-to-treat RA or RA-related lung disease.
ShanghaiAges 18 years+ - NCT07489534RecruitingPhase 2
CAR-T therapy for multiple myeloma with kidney problems
This trial tests a new type of cell therapy (CAR-T cells) for people with multiple myeloma who also have kidney problems. It aims to see if this treatment can help keep the cancer in remission after initial therapy.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07483853Recruiting
MRI scoring test for chronic bone inflammation in children
This study checks if a new MRI scoring system can reliably measure bone inflammation in children with a rare bone disease called CRMO. The goal is to improve how doctors monitor the disease.
BolognaAges Up to 32 years - NCT07487428Recruiting
Diet study for early-stage CLL
This study tests whether a whole-food plant-based diet for 4 weeks can affect immune function and metabolism in people with early-stage CLL who have not yet had treatment.
München, BavariaAges 18 years+ - NCT07487350Recruiting
Recurrent leishmaniasis in people with HIV
This study looks at better ways to treat visceral leishmaniasis (a serious parasitic infection) when it comes back in people who also have HIV. It may help find a plan that works longer and reduces the chance of relapse.
GonderAges 18 years+ - NCT07488728Recruiting
Letermovir to prevent CMV in children after stem cell transplant
This trial tests if the drug letermovir can prevent a common virus (CMV) in children who have certain blood disorders and are getting a stem cell transplant. It aims to keep you safer during recovery.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT07487311Recruiting
Study of guselkumab plus JAK inhibitors for tough-to-treat IBD
This trial tests a combination of two medications—guselkumab and a JAK inhibitor—for people with inflammatory bowel disease that hasn't responded to other treatments. The goal is to see if this combination is safe and effective for patients with hard-to-control Crohn's disease or ulcerative colitis.
Hangzhou, ZhejiangAges 14–80 - NCT07483879Recruiting
Organ Injury Biomarkers in Newly Diagnosed Type 1 Diabetes
This study looks at signs of acute organ injury in children newly diagnosed with type 1 diabetes. It aims to understand how the body reacts to diabetes and its treatment, which could help improve care for kids like yours.
Thessaloniki, Central MakedoniaAges 2–16 - NCT07488117RecruitingPhase 2
PET scan to detect brain inflammation in autoimmune encephalitis
This trial uses a special PET scan (with a tracer called [18F]-DPA-714) to see if it can measure inflammation in the brain caused by autoimmune encephalitis. The goal is to see if this scan can help doctors diagnose and monitor the condition more accurately.
ToulouseAges 18–80 - NCT07483476Recruiting
Cell-free DNA in children with new ALL
This study looks at a special blood test that measures cell-free DNA (tiny pieces of genetic material) in children with acute lymphoblastic leukemia (ALL). It aims to understand how this test might help monitor the disease, and it is for newly diagnosed children who haven't started treatment yet.
ParisAges Up to 18 years - NCT07487831RecruitingPhase 4
Salt intake and skin sodium in inflammatory skin disease
This study tests how salt in your diet affects sodium levels in your skin and its link to inflammatory skin conditions like eczema. It may help explain why some people's skin flares up after eating salty foods.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,050 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,115 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.