Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,050 recruiting studies in this area right now.
By phase
- Not applicable2,999
- Phase 21,056
- Phase 1792
- Phase 1/Phase 2437
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes130
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland199
- Alabama178
- Florida149
- Arizona148
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,050 total
- NCT07457580Recruiting
A real-world study of teplizumab for type 1 diabetes
This study looks at real-world outcomes in patients with type 1 diabetes who received teplizumab through managed access programs. It helps researchers understand how well the treatment works outside of a clinical trial setting.
LeuvenAges Any age - NCT07455851RecruitingPhase 1/Phase 2
Studying a new drug combo for relapsed or refractory multiple myeloma
This trial tests whether REGN17372 plus linvoseltamab is safe for people with multiple myeloma that has come back or not responded to prior treatments. You may join if you have tried at least 3 other therapies.
Randwick, New South WalesAges 18 years+ - NCT07456033RecruitingPhase 3
Depemokimab for adults and teens with type 2 asthma
This study tests a new medicine called depemokimab, given as an injection, to see if it can reduce asthma attacks in people with a specific type of asthma (type 2 high). If you have had asthma for several years and have had recent attacks despite using regular inhalers, this trial might be an option for you.
Little Rock, ArkansasAges 12 years+ - NCT07455578RecruitingPhase 1
Study of S-4321 for people with autoimmune or immune diseases
This trial tests a new medicine, S-4321, for people with various autoimmune conditions like rheumatoid arthritis, psoriasis, eczema, or lupus. It aims to see if the drug is safe and can help control the overactive immune system.
Charlestown, New South WalesAges 18–75 - NCT02103361Recruiting
Pregnancy registry for Stelara or Tremfya exposure
This study is a pregnancy exposure registry. It collects information to better understand pregnancy outcomes after exposure to Stelara or Tremfya (medicines used for autoimmune diseases).
La Jolla, CaliforniaAges Any age - NCT04449198RecruitingEarly Phase 1
Study for mitochondrial and blood-vessel issues in type 1 diabetes
This early study looks at how a new approach may affect energy-making (mitochondria) and blood-vessel signaling in people with insulin-dependent type 1 diabetes. It may help researchers understand whether these pathways can be improved in type 1 diabetes.
Augusta, GeorgiaAges 18 years+ - NCT05331170RecruitingPhase 2
Re-training the nose to change how allergies behave
This Phase 2 study tests a “viral” treatment meant to reprogram the lining of your nose to reduce allergy-like immune responses. It is testing whether this approach is safe and can help people with cat allergy (with or without asthma) or compare against healthy people.
Galveston, TexasAges 18–60 - NCT05938478Recruiting
Pregnancy registry for outcomes after tralokinumab exposure
This study tracks pregnancy and baby outcomes in people who have been pregnant while taking tralokinumab, a medication for eczema. It compares those outcomes to other eczema treatment groups to help doctors understand potential risks or reassuring effects.
La Jolla, CaliforniaAges Any age - NCT06100211Recruiting
HIV, gut health, and switching HIV meds study
This study looks at how changing your HIV medication affects the bacteria in your gut. You'll provide two stool samples so researchers can see what changes happen.
Manchester, Greater ManchesterAges 18 years+ - NCT07454382RecruitingPhase 2
Study of elranatamab and cyclophosphamide for multiple myeloma
This trial studies a new medicine called elranatamab combined with the chemotherapy drug cyclophosphamide for people with multiple myeloma that has returned or not responded to prior treatments. It may be a good option if you have aggressive or high-risk myeloma.
Basking Ridge, New JerseyAges 18 years+ - NCT07455396RecruitingPhase 2
Dexamethasone vs methylprednisolone for children with severe asthma
This trial compares two steroids, dexamethasone and methylprednisolone, to see which works better for children in the intensive care unit with severe asthma. The goal is to find the best treatment with fewer side effects.
St. Petersburg, FloridaAges 3–17 - NCT07461896Recruiting
Nerve function study in Charcot-Marie-Tooth and related neuropathies
This study looks at how nerves work and their structure in people with Charcot-Marie-Tooth disease, CIDP, or anti-MAG neuropathy. It may help doctors better understand these conditions.
MilanAges 18 years+ - NCT07454226Recruiting
Drug combo for Ph-like acute lymphoblastic leukemia
This trial tests a combination of targeted drugs (ABL/JAK inhibitors) with chemotherapy and venetoclax for people with a type of leukemia called Ph-like ALL. It aims to see if this treatment is safe and effective.
Tianjin, Tianjin MunicipalityAges 14–60 - NCT07456358Recruiting
Immune attack targets in brain disease
This study looks at the immune system's role in neurological problems caused by cancer immunotherapy or autoimmune diseases. Researchers will collect spinal fluid to find out which immune targets are involved, which may help improve diagnosis and treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07456657Recruiting
Lavender massage for pain and wrist mobility in rheumatoid arthritis
This trial tests whether lavender aromatherapy massage can reduce pain and improve wrist movement in people with rheumatoid arthritis. If you have stable RA and positive rheumatoid factor, you may be able to join.
Hillah, Babil GovernorateAges 20–60 - NCT07460362RecruitingPhase 2
Glofitamab and lenalidomide for high-risk mantle cell lymphoma
This trial tests a combination of two drugs, glofitamab and lenalidomide, for people with mantle cell lymphoma that has come back or not responded to treatment. It's for those with high-risk features, like a fast-growing lymphoma or resistance to previous therapies.
Beijing, Beijing MunicipalityAges 18–80 - NCT07461350Enrolling by invitation
Heart health study in people with and without HIV
This study uses MRI scans to look at how stimulant use and inflammation affect the heart in people with and without HIV. It aims to learn more about heart disease risks and may help guide future care.
San Francisco, CaliforniaAges 30 years+ - NCT07461805Recruiting
Understanding type 1 diabetes with AI and glucose data
This study uses artificial intelligence to analyze glucose monitor data from people with type 1 diabetes. The goal is to find patterns that could improve care and treatment.
Barcelona, BarcelonaAges 18 years+ - NCT07462338Enrolling by invitation
Walking test reliability in multiple sclerosis patients
This study checks how reliable a simple walking test (Timed Up and Go) is for people with multiple sclerosis, especially when they do another task at the same time. It aims to improve how doctors measure walking ability.
Gaziantep, GaziantepAges 18–65 - NCT05654675Recruiting
Scan method study for measuring tumor sugar use on PET
This study checks whether a specific analysis method (called FUR) can better measure how much “sugar” from PET scans is used by tumors. It uses regular PET/CT scans you may already get as part of standard care, and compares how the measurements work.
Maastricht, LimburgAges 18 years+ - NCT06778213RecruitingPhase 4
Allergy shots for dust mite allergies tested in a special room
This trial tests if allergy shots (allergen-specific immunotherapy) can reduce symptoms of moderate to severe dust mite allergy. You will be in a room that exposes you to dust mites to see how well the treatment works, compared to a placebo.
Wroclaw, DLAges 18–65 - NCT06796517Recruiting
Immunotherapy for relapsed or refractory lymphoma
This trial tests immunotherapy for people with certain types of lymphoma (diffuse large B cell, primary mediastinal, high grade, or Burkitt) that came back or didn't respond to previous treatment. It aims to see if a new immune-based approach can help.
SeoulAges 19–74 - NCT06626672Recruiting
Digital Health Program for Kids with Heart Defects
This study uses digital tools to promote healthy habits in children (ages 8–14) with congenital heart disease. It aims to support both the child and their family in staying active and well.
MünchenAges 8–14 - NCT06328504Recruiting
Cashew allergy treatment with cashew protein
This trial tests whether giving very small amounts of cashew protein (like a food immunotherapy) can help children and teens with cashew allergy become less allergic. If it works, it might lower the risk of severe reactions.
Warsaw, Masovian VoivodeshipAges 4–17
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,050 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,115 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.