Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,143
- Phase 21,065
- Phase 1821
- Phase 1/Phase 2445
- Phase 3424
- Phase 4238
- Phase 2/Phase 394
Top conditions
- Multiple Sclerosis341
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis141
- Type 1 Diabetes133
- Atopic Dermatitis128
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Acute Myeloid Leukemia62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals63
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland196
- Alabama175
- Florida143
- Arizona140
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT05147688RecruitingPhase 1
Safety study of donor stem cell treatment for lung disease
This early study tests whether donor stem cells made from umbilical cord tissue are safe in people with lung diseases. If you qualify, you may be offered the study treatment while the team closely checks for side effects and safety.
St John'sAges Any age - NCT05152238Recruiting
ITP registry and optional blood sample collection study
This study helps doctors better understand immune thrombocytopenia (ITP) by collecting basic patient information and, if you agree, storing blood samples. It may help future care decisions and research for people with ITP.
AachenAges 18 years+ - NCT05153070RecruitingPhase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes
This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.
ParisAges 16–45 - NCT05153057Recruiting
Follow-up study for birdshot eye inflammation
This study follows people with “birdshot chorioretinopathy,” a rare eye inflammation, and collects immune (genetic) information to better understand the disease. You may benefit from closer monitoring, and the results may help guide future treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT05154370Recruiting
Registry for neuroinflammation diseases and diagnosis categories
This study is a registry that collects information from people diagnosed with certain neuroinflammation conditions. It may help doctors learn how these diseases behave over time and support future research.
Beijing, Beijing MunicipalityAges Any age - NCT05156203RecruitingPhase 1
T-1301 capsules test for advanced solid tumor cancers
This early-phase study tests whether T-1301 capsules are safe and how well they can work in people with advanced solid tumors that can’t be treated with standard options. It focuses on side effects first, but results may help guide future treatment for advanced cancers.
Kaohsiung CityAges 20 years+ - NCT05157685RecruitingPhase 3
Azithromycin for chronic pus-filled sinus inflammation
This Phase 3 trial tests whether the antibiotic azithromycin can improve chronic sinus problems where there is persistent pus and swelling. It’s for adults who have not improved despite at least two prior antibiotics.
BordeauxAges 18–70 - NCT05157581Recruiting
Light-based treatment for Sezary syndrome patients
This trial tests whether a special light treatment done outside the body (extracorporeal photopheresis) can help people with Sezary syndrome. It is meant to see if the treatment is safe and effective for this specific type and stage of skin lymphoma.
Atlanta, GeorgiaAges 18–100 - NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT05159856Recruiting
Early checks for long-term complications in young type 1 diabetes
This study looks for early signs of long-term complications in children and teens who have type 1 diabetes for more than a year. It may help your clinic spot problems sooner, when treatment could be easier.
Herlev, HerlevAges 6–18 - NCT05168930RecruitingPhase 2
Zanubrutinib plus venetoclax for relapsed CLL or SLL
This Phase 2 study tests how well zanubrutinib (a targeted pill) combined with venetoclax (another targeted pill) works for adults with CLL/SLL that came back or progressed after prior treatment. It may help by stopping cancer cells through two different pathways, aiming to shrink disease and improve blood counts.
Scarborough, MaineAges 18 years+ - NCT05170126Recruiting
Study of ozanimod use during pregnancy in people with MS
This trial looks at the safety of ozanimod taken during pregnancy for parents with multiple sclerosis and for their babies after birth. It may help doctors understand the risks and benefits of this medicine during early pregnancy.
Bethesda, MarylandAges Any age - NCT05170347Recruiting
Study of graft-versus-host disease after bone marrow transplant
This study follows people after an allogeneic bone marrow transplant to understand a complication called graft-versus-host disease. If you can attend follow-up visits, your experience and samples may be compared with a family control to look for differences.
Hong KongAges 18 years+ - NCT05170633Recruiting
Warming treatment for very preterm babies after blood transfusion
This study looks at whether a specific “blood warming” approach can help very preterm babies keep their body temperature from getting too low (hypothermia). It’s intended to reduce temperature drops around the time they receive red blood cell transfusions.
Columbia, South CarolinaAges 6 months–7 months - NCT05171478Recruiting
Test imaging on small lung biopsy samples during bronchoscopy
This study uses a special eye-like scanning camera (full-field optical coherence tomography) to look at tiny lung tissue samples taken during routine bronchoscopy. It may help doctors learn more from small biopsies used to diagnose or stage lung problems.
Baltimore, MarylandAges 18 years+ - NCT05180097RecruitingPhase 2
Immunotherapy with stem cell transplant for relapsed Hodgkin lymphoma
This Phase 2 trial tests whether pembrolizumab plus brentuximab works better than standard chemotherapy followed by an autologous stem cell transplant for people whose classic Hodgkin lymphoma has come back or did not respond. It may help by improving cancer control before and around stem cell transplant and by comparing outcomes between the two treatment approaches.
Concord, New South WalesAges 18 years+ - NCT05177523Recruiting
MRI study of nerve damage and repair in multiple sclerosis
This trial uses MRI scans to better understand how nerve fibers are damaged and repaired in people with multiple sclerosis. It may help researchers connect scan findings to disease activity and progression.
BaselAges 18–80 - NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT05180578Recruiting
Goat milk protein study for children with milk-triggered esophagus inflammation
This trial tests whether goat milk protein is tolerated and safe for kids with eosinophilic esophagitis (EoE) whose symptoms improve when cow milk is stopped and come back when cow milk is added again. It may help some families find an alternative to cow milk, but you must meet specific “milk trigger” and allergy-safety requirements.
JerusalemAges Up to 18 years - NCT05182957RecruitingPhase 2
Study of anti-PD-1, lenalidomide, and azacitidine for PTCL
This trial tests a combination of three medicines (anti-PD-1, lenalidomide, and azacitidine) for adults with relapsed or refractory peripheral T-cell lymphoma (PTCL) that is measurable or growing. It aims to shrink lymphoma and improve control of the disease when standard treatments haven’t worked or have stopped working.
Suzhou, JiangsuAges 18 years+ - NCT05183854RecruitingPhase 2
Vaccine study for CLL patients to prevent pneumococcal infections
This trial tests a series of two pneumococcal vaccines (PCV20 and PPSV23) in people with CLL-related immune weakness. It aims to see how well the vaccines work and how safe they are for preventing serious lung infections.
Salt Lake City, UtahAges 18 years+ - NCT05188027Recruiting
Exercise types for postmenopausal women with type 1 diabetes
This study compares aerobic exercise (like brisk walking) versus resistance exercise (like strength training) to see which works better for women with type 1 diabetes after menopause. It may help you learn which exercise approach is safest and most helpful for blood sugar and health.
Edmonton, AlbertaAges 45–75 - NCT05190653Recruiting
Support during stem cell or CAR T cancer treatment
This study tests whether starting palliative and supportive care early (alongside cancer treatment) can improve comfort and support for people having stem cell transplant or CAR T-cell therapy. It may also help family caregivers by offering support during a difficult treatment period.
Calgary, AlbertaAges 18 years+ - NCT05190848Recruiting
Study of gut microbes and blood chemicals in IgA kidney disease
This trial looks at how bacteria in the gut (microbiome) and substances in the body (metabonomics) relate to IgA nephropathy, a kidney condition. The goal is to understand patterns that may help explain the disease and improve future care.
Guangzhou, GuangdongAges 16–65
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,742 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.