Treatment
0.9% Saline clinical trials
We’re tracking 85 recruiting studies that include 0.9% Saline, each written for real people, not researchers, below.
Recruiting studies
- NCT05169814RecruitingEarly Phase 1
Microbubble treatment for certain burn and wound types
This early-stage study tests micro/nanobubbles placed on or used for certain types of difficult wounds, including burns and some pressure or diabetic foot ulcers, especially when there has been tissue injury from radiation. It may help wounds heal faster or more effectively, but it is still being studied in early phases.
Orange, CaliforniaAges 18 years+ - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT04928300RecruitingPhase 3
Low-dose pain medicine vs saline for broken ribs
This Phase 3 study tests whether low-dose dexmedetomidine (a calming/pain-related medicine used during anesthesia or ICU care) works better than normal saline to reduce hard-to-control rib fracture pain. It may help people with multiple broken ribs who still have significant pain despite other treatments.
Asyut, AssuitAges 18–65 - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT05531630Enrolling by invitation
Xylitol versus saline rinses for sinus symptoms in adults with CF
This study compares two kinds of nasal rinse packets—xylitol versus plain saline—to see which better reduces sinus symptoms. It may help adults with cystic fibrosis and long-term sinus inflammation feel better with routine, at-home nasal care.
LeuvenAges 18 years+ - NCT06953674RecruitingPhase 3
Saline versus balanced fluids for traumatic brain injury
This trial compares two types of intravenous fluids (saline vs. balanced crystalloids) given to people with traumatic brain injury when they arrive in the emergency room. The goal is to find out which fluid leads to better outcomes.
Louisville, KentuckyAges 18 years+ - NCT05989386RecruitingPhase 2/Phase 3
Washing the belly to prevent infections after emergency surgery
This trial compares two solutions (salt water vs. povidone-iodine antiseptic) used to clean the belly during emergency surgery. The goal is to see which one better prevents wound infections.
Karachi, SindhAges 18–60 - NCT04126876RecruitingPhase 2
IMO-2125 skin injection for thick, early-stage melanoma
This trial tests whether an injection given into the skin (IMO-2125) can improve outcomes for people with thicker primary melanoma that has not spread to lymph nodes or other organs. Participants also have planned surgery to remove the tumor and check a sentinel lymph node.
AmsterdamAges 18 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT04916197RecruitingPhase 4
Dexmedetomidine sedation after stroke clot removal
This Phase 4 study tests whether using a specific calming medicine (dexmedetomidine) for a longer period after a successful clot-removal procedure helps people do better in the long term. It may help improve outcomes after ischemic stroke where the clot is successfully treated.
Beijing, Beijing MunicipalityAges 18–80 - NCT07855380Recruiting
Ultrasound-guided pain block for chronic pain after cancer surgery
This study tests a pain-relieving injection placed near the belly muscles using ultrasound guidance, to see if it helps reduce long-term pain after abdominal surgery for cancer. It may offer a new way to manage pain without strong painkillers.
CairoAges 18–65 - NCT07846722Recruiting
Comparing two medicines to reduce pain medicine use after laparoscopic hysterectomy
This study compares two drugs, esmolol and dexmedetomidine, to see which one better reduces the need for strong painkillers after laparoscopic hysterectomy. It may help you manage pain with fewer opioids.
AthensAges 20–70 - NCT07824817RecruitingPhase 4
Sedation options for electroconvulsive therapy
This study compares two medicines used during electroconvulsive therapy (ECT) to see which one causes fewer side effects and works better. ECT is a treatment for certain mental health conditions that uses electrical stimulation to the brain while you are asleep.
Malatya, BattalgaziAges 18–60 - NCT07722091Recruiting
Steroid spray to prevent hoarseness after abdominal surgery
This study tests a new way to prevent hoarseness after upper abdominal surgery by spraying a steroid (dexamethasone) near certain nerves during the operation. The goal is to reduce voice changes that can happen from the breathing tube or surgical stress.
Fuzhou, FujianAges 18–75 - NCT07693244RecruitingPhase 2
Exosome therapy for male pattern baldness
This trial tests a new treatment using exosomes (tiny particles that help cells communicate) for male pattern baldness. It may help regrow hair or slow further loss.
BeijingAges 18–55 - NCT07687589Enrolling by invitation
Testing a gut hormone for nausea in healthy adults
This study tests whether a natural gut hormone called GIP can reduce nausea by increasing blood flow to the gut. Researchers want to see how this works in healthy people.
HellerupAges 18–60 - NCT07672873Recruiting
Steroid injection for tooth nerve pain during root canal
This trial tests whether a single injection of dexamethasone (a steroid) near the nerve of a painful lower molar can improve pain relief during a root canal. It's for people with severe tooth nerve pain who haven't taken pain meds recently.
IstanbulAges 18–65 - NCT07661758RecruitingPhase 3
Lidocaine to prevent headache after C-section
This trial tests if giving lidocaine through an IV can prevent the headache that sometimes happens after spinal anesthesia during a planned C-section. If you are having a planned C-section with spinal anesthesia and meet other health requirements, this study might help reduce your risk of post-procedure headache.
Tanta, Gharbia GovernorateAges 18 years+ - NCT07643298Recruiting
Lidocaine through feeding tube to reduce nausea after weight-loss surgery
This study tests whether delivering lidocaine (a numbing medication) through a feeding tube during weight-loss surgery can reduce nausea and vomiting afterward. You would receive this medication as part of the surgery procedure to see if it helps you feel better in recovery.
Yinchuan, NingxiaAges 18–65 - NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT07584525RecruitingPhase 3
Dexamethasone treatment for tick-borne encephalitis
This study tests whether a steroid medication called dexamethasone can help people with tick-borne encephalitis, a serious brain infection spread by ticks. The goal is to see if this treatment reduces inflammation in the brain and improves recovery.
LjubljanaAges 18 years+ - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07547228RecruitingPhase 1/Phase 2
PRL3-zumab for advanced age-related macular degeneration
This study tests a new injectable medicine called PRL3-zumab for patients with advanced wet macular degeneration (nAMD) whose condition hasn't improved enough with standard treatments. The goal is to see if this new approach can help preserve or improve vision in people who have already tried at least two other eye injections.
SingaporeAges 18 years+ - NCT07549542Enrolling by invitationPhase 4
Testing antibiotic delivery method for hip replacement surgery
This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.
Somerset, New JerseyAges 18 years+
What 0.9% Saline is being studied for
Conditions with recruiting 0.9% Saline studies.
Common questions
- Are there clinical trials studying 0.9% Saline?
- Yes. Clin2 currently lists 85 recruiting studies that include 0.9% Saline, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a 0.9% Saline trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is 0.9% Saline an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether 0.9% Saline or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.