Treatment
0.9% Saline clinical trials
We’re tracking 84 recruiting studies that include 0.9% Saline, each written for real people, not researchers, below.
Recruiting studies
- NCT05169814RecruitingEarly Phase 1
Microbubble treatment for certain burn and wound types
This early-stage study tests micro/nanobubbles placed on or used for certain types of difficult wounds, including burns and some pressure or diabetic foot ulcers, especially when there has been tissue injury from radiation. It may help wounds heal faster or more effectively, but it is still being studied in early phases.
Orange, CaliforniaAges 18 years+ - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT04928300RecruitingPhase 3
Low-dose pain medicine vs saline for broken ribs
This Phase 3 study tests whether low-dose dexmedetomidine (a calming/pain-related medicine used during anesthesia or ICU care) works better than normal saline to reduce hard-to-control rib fracture pain. It may help people with multiple broken ribs who still have significant pain despite other treatments.
Asyut, AssuitAges 18–65 - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT05531630Enrolling by invitation
Xylitol versus saline rinses for sinus symptoms in adults with CF
This study compares two kinds of nasal rinse packets—xylitol versus plain saline—to see which better reduces sinus symptoms. It may help adults with cystic fibrosis and long-term sinus inflammation feel better with routine, at-home nasal care.
LeuvenAges 18 years+ - NCT06953674RecruitingPhase 3
Saline versus balanced fluids for traumatic brain injury
This trial compares two types of intravenous fluids (saline vs. balanced crystalloids) given to people with traumatic brain injury when they arrive in the emergency room. The goal is to find out which fluid leads to better outcomes.
Louisville, KentuckyAges 18 years+ - NCT05989386RecruitingPhase 2/Phase 3
Washing the belly to prevent infections after emergency surgery
This trial compares two solutions (salt water vs. povidone-iodine antiseptic) used to clean the belly during emergency surgery. The goal is to see which one better prevents wound infections.
Karachi, SindhAges 18–60 - NCT07052903RecruitingPhase 3
RNA therapy for ATTR amyloidosis with heart involvement
This trial tests an experimental RNA therapy (nucresiran) for people with transthyretin amyloidosis that causes heart problems (cardiomyopathy). It aims to lower the abnormal protein buildup to help heart function.
La Jolla, CaliforniaAges 18–85 - NCT06823349RecruitingPhase 4
Pain relief study for normal labor
This trial compares a single injection of pain medicine into the spinal fluid to other methods during normal labor. It aims to see how well it works for women in active labor with a single, full-term baby in head-down position.
AswānAges Any age - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT06406010RecruitingPhase 4
Nerve block for pain after hip surgery
This trial tests whether a specific nerve block can reduce pain after a hip socket surgery. The results could help improve recovery and reduce the need for strong painkillers.
CopenhagenAges 18 years+ - NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65 - NCT07473128RecruitingPhase 3
Trilaciclib to prevent low blood cell counts in limited-stage small cell lung cancer
This trial tests whether taking trilaciclib alongside standard chemotherapy can help prevent low blood cell counts (myelosuppression) in people with limited-stage small cell lung cancer. It may help you stay stronger during treatment.
Oakland, CaliforniaAges 18 years+ - NCT07409727RecruitingPhase 4
Acetylcysteine inhalation to prevent pneumonia in ventilated patients
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
CairoAges 18–64 - NCT07370129Enrolling by invitation
Numbing injection for pain after tonsil surgery
This study tests a numbing injection near a nerve in your nose to see if it can reduce pain and help you recover faster after tonsillectomy. It is a non-drug approach that may offer an alternative to strong pain medicines.
Ankara, AnkaraAges 12 years+ - NCT07549542Enrolling by invitationPhase 4
Testing antibiotic delivery method for hip replacement surgery
This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.
Somerset, New JerseyAges 18 years+ - NCT07193836Enrolling by invitation
Lidocaine for easier recovery after laparoscopic surgery
This study tests whether giving lidocaine (a numbing medicine) through an IV can help you wake up more smoothly and with less discomfort after laparoscopic gallbladder or gynecologic surgery. If you are generally healthy and having one of these specific surgeries, you may be a good fit.
Yinchuan, NingxiaAges 18–70 - NCT07643298Recruiting
Lidocaine through feeding tube to reduce nausea after weight-loss surgery
This study tests whether delivering lidocaine (a numbing medication) through a feeding tube during weight-loss surgery can reduce nausea and vomiting afterward. You would receive this medication as part of the surgery procedure to see if it helps you feel better in recovery.
Yinchuan, NingxiaAges 18–65 - NCT06812390RecruitingPhase 2
Albumin plus diuretics for cirrhosis-related leg swelling
This study tests whether giving albumin (a protein) along with water pills helps reduce leg swelling in people with cirrhosis and ascites. It may be an option if your leg swelling hasn't improved with standard diuretics alone.
West Haven, ConnecticutAges 18 years+ - NCT07547228RecruitingPhase 1/Phase 2
PRL3-zumab for advanced age-related macular degeneration
This study tests a new injectable medicine called PRL3-zumab for patients with advanced wet macular degeneration (nAMD) whose condition hasn't improved enough with standard treatments. The goal is to see if this new approach can help preserve or improve vision in people who have already tried at least two other eye injections.
SingaporeAges 18 years+ - NCT07448129Recruiting
Testing SUBMO for removing large colon growths
This trial tests a new liquid called SUBMO that doctors inject under large growths in the colon to make them easier to remove during a colonoscopy. It may help people who need a colon polyp or other lesion removed.
Barcelona, BarcelonaAges 18 years+ - NCT04126876RecruitingPhase 2
IMO-2125 skin injection for thick, early-stage melanoma
This trial tests whether an injection given into the skin (IMO-2125) can improve outcomes for people with thicker primary melanoma that has not spread to lymph nodes or other organs. Participants also have planned surgery to remove the tumor and check a sentinel lymph node.
AmsterdamAges 18 years+ - NCT04182997RecruitingPhase 4
Epidural steroid shot during discectomy for back nerve pain
This trial studies whether giving a steroid medicine into the epidural space during discectomy (back surgery for a herniated disc) helps reduce nerve pain and symptoms. It is mainly for people whose MRI and exam show a single-level lumbar disc herniation after non-surgical treatments didn’t help.
Columbia, MissouriAges 18 years+
What 0.9% Saline is being studied for
Conditions with recruiting 0.9% Saline studies.
Common questions
- Are there clinical trials studying 0.9% Saline?
- Yes. Clin2 currently lists 84 recruiting studies that include 0.9% Saline, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a 0.9% Saline trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is 0.9% Saline an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether 0.9% Saline or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.