Carbon Dioxide clinical trials

Breathing gas and nausea after hysterectomy study

This study looks at whether levels of carbon dioxide in your breath and blood flow measurements during surgery can help predict nausea, vomiting, or pain after a hysterectomy. It may help doctors better manage your recovery.

Non-invasive treatment for brain fog from long COVID

This study tests a non-invasive treatment to help with brain fog caused by long COVID. It may improve your symptoms if you have trouble thinking clearly or focusing.

Continuous skin carbon dioxide monitoring in heart-lung bypass patients

This study checks whether a sensor placed on the skin can reliably measure carbon dioxide levels in people who need VA-ECMO, a kind of temporary heart-lung support. It aims to help doctors monitor breathing and circulation more accurately while you’re on this support.

Comparing two CO2 detectors during breathing tube placement in critically ill adults

This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.

Carbon dioxide removal to protect lungs during ARDS

This study tests a machine that removes carbon dioxide from your blood (called extracorporeal carbon dioxide removal or ECCO2R) to help protect your lungs from further damage while on a breathing machine. It may be an option if you have severe ARDS and your breathing machine settings are very high.

Breathing extra carbon dioxide during surgery to prevent brain injury

This trial tests whether giving extra carbon dioxide during surgery can reduce the chance of new brain or nervous system injury after surgery for a sudden, life-threatening tear in the big artery (type A aortic dissection). It may help by protecting the brain while the surgical team repairs the artery.

CO2 measurement test on exercise bike

This trial checks if a portable device can reliably measure carbon dioxide in your breath while you rest and cycle slowly. It may help understand how your lungs work during light exercise.

Reducing air bubbles during aortic repair with carbon dioxide

This trial tests a special flushing method using carbon dioxide gas to prevent air bubbles from entering the bloodstream during a procedure to fix the main artery in the chest. This could help avoid strokes or other complications.

Testing how your brain responds to carbon dioxide in epilepsy

This study measures how sensitive your brain is to higher carbon dioxide levels to learn more about sudden unexpected death in epilepsy (SUDEP). You may be invited because you have epilepsy and are having evaluation at a specialized epilepsy unit or clinic.

Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography

Genetic changes in tracheal narrowing with two treatments

This trial studies genetic changes in people with tracheal stenosis (narrowing of the windpipe). It compares two treatments: wedge resection (cutting out the narrow part) and radial incision (cutting to open it up). This may help doctors choose the best treatment in the future.

Exercise and breathing study for young adults with vocal cord issues

This study looks at how the vocal cords move during exercise in young adults who have trouble breathing while active. It may help researchers understand why this happens and how to better diagnose and treat it.

Using a carbon dioxide monitor to guide safe breathing-tube removal

This study tests a special carbon dioxide monitor to help decide when it's safe to remove your breathing tube after abdominal surgery. If you are having a planned abdominal procedure lasting 1–4 hours, you may be able to join.

Laser treatment with or without PDRN for facial scars

This study tests if adding a substance called PDRN to a laser treatment helps improve the look of new facial scars better than laser alone. PDRN may help the skin heal more smoothly.

Platelet-rich plasma plus CO2 laser for acne scars

This study tests whether combining your own blood proteins (PRP) with a fractional CO2 laser can improve moderate-to-severe acne scars more than laser alone. You would have 3 treatment sessions spaced several weeks apart.

Carbon dioxide pressure and eye nerve sheath in kidney surgery

This study looks at how the carbon dioxide gas used during keyhole kidney cancer surgery affects the pressure behind your eye. The goal is to see if changes in gas pressure influence the nerve sheath that surrounds the optic nerve.

Breathing tube study for avalanche burial simulation

This study tests whether a special breathing tube changes carbon dioxide levels in the body during a simulated avalanche burial. It helps researchers understand how to better protect people trapped under snow.

Compression and CO2 laser for lower leg wounds

This study looks at whether using leg compression and a CO2 laser after lower-leg wound surgery helps wounds heal better. You may be a candidate if you have a sizeable lower-leg wound that will be treated with a specific type of surgical healing plan.

Skin response to fractional laser treatments in darker skin tones

This study measures how skin changes after two types of laser treatments (gentler and stronger) on the forearm. Researchers want to understand how these lasers work on darker skin types to improve safety and results.

MRI study of brain oxygen use in children and adults

This study uses an MRI scan to measure how your brain uses oxygen. It includes healthy participants and people with sickle cell disease or who previously needed ECMO, which may help researchers understand brain oxygen problems and how to monitor them.

Breathing gas study during clot removal for stroke

This Phase 2 trial tests whether changing breathing gas (CO₂ level) during a mechanical procedure to remove a brain blood clot can improve outcomes for acute ischemic stroke. It may help by protecting the brain during the clot-removal procedure under general anesthesia.

Using breath CO2 levels to judge COPD flare severity in ER

This study measures an easy breathing signal called end-tidal carbon dioxide (a CO2 reading from your exhaled breath) to help judge how severe a COPD flare is. It may help doctors decide how closely you need monitoring and treatment during emergency care.

Study of oxygen side effects in otherwise healthy adults

This study looks at what happens in the body when oxygen levels are too high, to better understand the mechanism of oxygen toxicity. You may be eligible if you are a healthy, non-smoking adult without certain medical conditions.

Carbon dioxide gas for children's endoscopy

This study tests if carbon dioxide gas is safe and works well for children getting an endoscopy. An endoscopy is a procedure where a doctor uses a thin tube to look inside the body.