Treatment
Dexmedetomidine clinical trials
We’re tracking 191 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07327931Recruiting
Comparing two PENG block recipes for hip surgery in older adults
This study tests two different types of local numbing medicine (with and without extra additives) for a nerve block called PENG block in older adults having hip surgery. The goal is to find which method controls pain better and reduces the need for strong pain relievers.
PoznanAges 65–100 - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT03382938Recruiting
Dexmedetomidine injected into C-section wounds
This trial studies whether a specific numbing/comfort medicine (dexmedetomidine) injected into the wound area during a C-section can improve recovery or reduce symptoms after surgery. You may be able to take part if you are a low-risk pregnancy and meet safety requirements.
Athens, OtherAges 18–40 - NCT05361837Recruiting
Nerve block with sedation for breast surgery comfort
This trial tests if adding a numbing injection (serratus anterior plane block) with a calming medicine (dexmedetomidine) helps reduce pain during and after breast removal surgery.
Cairo, Cairo GovernorateAges 18–65 - NCT07443085RecruitingPhase 2
Dexmedetomidine dose and delirium risk after orthopedic surgery
This trial tests different doses of a medicine called dexmedetomidine to see if it can reduce confusion (delirium) after major leg surgery in older adults. If you are 65 or older and planning to have hip or knee replacement surgery, you may be eligible.
Banhā, Al QalyobiaAges 55–70 - NCT07479602RecruitingPhase 4
Medicine via nose for less pain after tonsil surgery in kids
This trial tests whether giving two medicines (dexmedetomidine and esketamine) through the nose can help children ages 3-7 have less pain after their tonsil or adenoid surgery. The goal is to find a better way to manage pain without using strong drugs.
Beijing, Beijing MunicipalityAges 3–7 - NCT07556133Recruiting
Comparing two sedation medicines during cataract surgery
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
BeirutAges 18 years+ - NCT07767383RecruitingPhase 4
Improving sleep quality after knee surgery with added sedation and nerve blocks
This trial tests whether adding a calming medicine called dexmedetomidine to a nerve block around the knee can help you sleep better after arthroscopic knee surgery. It aims to find if this combination reduces sleep problems during recovery.
Nantong, JiangsuAges 18–85 - NCT07769255Recruiting
Nebulized dexmedetomidine for early chronic migraine
This trial tests whether a medicine called dexmedetomidine, given through a nebulizer (mist you breathe in), can help reduce the number of headache days and prevent migraines from becoming chronic. It is for people who have recently started having many headache days each month.
Banī SuwayfAges 18–55 - NCT07705022Enrolling by invitationPhase 2
Brain activity study during light sedation
This study uses brain scans (fMRI) to see if people who are lightly sedated can still think or respond. Researchers want to understand 'covert consciousness' during sedation with two common medicines, dexmedetomidine and ketamine.
Ann Arbor, MichiganAges 18–40 - NCT03384563RecruitingPhase 4
Testing a sedative’s effect on anesthesia dose needs in toddlers
This study looks at whether dexmedetomidine changes the minimum amount of sevoflurane (an inhaled anesthesia medicine) needed during surgery in young children. It may help doctors choose safer, more accurate anesthesia dosing for kids undergoing surgery.
Houston, TexasAges 1 month–3 years - NCT07154849RecruitingPhase 4
Preventing shivering after abdominal surgery with two IV drugs
This trial tests two intravenous medicines—hydrocortisone and dexmedetomidine—to see which one works better at preventing shivering after abdominal surgery. It may help you stay comfortable and recover more smoothly.
CairoAges 18–65 - NCT07056244Recruiting
Comparing two pain medicines for children’s hernia surgery
This study tests whether adding dexmedetomidine or dexamethasone to the standard numbing medicine (bupivacaine) provides better pain relief for children getting hernia surgery. The medicine is given through a shot in the lower back (caudal epidural block) to help keep your child comfortable during and after the operation.
SohagAges 2–6 - NCT06473896Recruiting
Pain relief after gallbladder surgery using ketamine or dexmedetomidine
This trial tests if adding ketamine or dexmedetomidine during anesthesia can prevent increased pain after surgery. It may help people having laparoscopic gallbladder removal feel better after the procedure.
Be’er Ya‘aqovAges 18–85 - NCT06274333RecruitingPhase 3
Easing bladder discomfort after kidney stone surgery
This trial tests if adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder pain and discomfort from the urinary catheter used during kidney stone removal. It may help patients feel more comfortable after their procedure.
Cairo, Cairo GovernorateAges 20–50 - NCT04730609RecruitingPhase 4
Dexmedetomidine to reduce shaking during scheduled C-section
This trial tests whether dexmedetomidine, a calming medicine, can reduce unwanted shaking (shivering) during a planned C-section done with spinal anesthesia. It may help make the surgery and recovery more comfortable.
Rochester, MinnesotaAges 18 years+ - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90 - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT06259565RecruitingPhase 3
Breathing mask sedation trial for agitated adults
This trial tests whether adding a sedative called dexmedetomidine to non-invasive ventilation (a breathing mask) helps adults who are agitated or uncomfortable while on the mask. It aims to improve comfort and avoid the need for a breathing tube.
Surrey, British ColumbiaAges 18 years+ - NCT07271147Recruiting
Nerve stimulation plus sedative for post-op nausea
This study tests whether combining a very mild nerve stimulation (taVNS) with a sedative (dexmedetomidine) can reduce nausea and vomiting after laparoscopic surgery. It may be a good option if you are scheduled for keyhole surgery and want to feel better afterward.
Nantong, JiangsuAges 18–65 - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60 - NCT07550881RecruitingPhase 2
Intranasal Dexmedetomidine for Sudden Anxiety in Adults
This study tests whether a medication called dexmedetomidine, given as a nasal spray, can quickly relieve sudden anxiety. The goal is to see if this approach works better or faster than current treatments for acute anxiety episodes.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06752863RecruitingPhase 4
Study of two drugs for controlled low blood pressure during surgery
This trial compares two medications, labetalol and dexmedetomidine, given as infusions to lower blood pressure during ear, nose, and throat surgeries. The goal is to find which drug works better and safer for patients.
Cairo, Cairo GovernorateAges 20–50 - NCT06970626RecruitingPhase 2/Phase 3
Comparing pain relief methods after sleeve gastrectomy
This study compares two ways to manage pain after laparoscopic sleeve gastrectomy: one uses a medication called dexmedetomidine given through an IV, and the other uses a combination of nerve blocks (TAP block and paragastric block) to see which leads to a better recovery.
AlexandriaAges 20–60
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 191 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.