Treatment
Dexmedetomidine clinical trials
We’re tracking 178 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT06853431RecruitingPhase 4
Pre-surgery calming medicine for children ages 1 to 6
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Wenzhou, ZhejiangAges 1–6 - NCT06030804Recruiting
Dexmedetomidine during surgery and long-term survival
This trial studies whether adding a medication called dexmedetomidine during cancer surgery can improve long-term survival. It is for older adults having major cancer surgery that lasts at least two hours and who will need a pain pump after the operation.
Hefei, AnhuiAges 60 years+ - NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06192615RecruitingPhase 3
Can a sleep medication protect the brain after heart surgery?
This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.
Los Angeles, CaliforniaAges 60 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05361837Recruiting
Nerve block with sedation for breast surgery comfort
This trial tests if adding a numbing injection (serratus anterior plane block) with a calming medicine (dexmedetomidine) helps reduce pain during and after breast removal surgery.
Cairo, Cairo GovernorateAges 18–65 - NCT07878156RecruitingPhase 3
Numbing medicine for children having brain tumor surgery
This study tests whether adding a numbing medicine to the standard pain block can reduce pain after brain surgery in children. It may help children feel more comfortable and recover more smoothly.
CairoAges Up to 18 years - NCT07878533RecruitingPhase 2
Ear surgery pain relief with added medication
This study tests whether adding a sedative medicine to the numbing shot around the ear nerve can improve pain control during and after middle ear surgery. It aims to make the procedure more comfortable and reduce the need for strong painkillers.
MinyaAges 18–70 - NCT04916197RecruitingPhase 4
Dexmedetomidine sedation after stroke clot removal
This Phase 4 study tests whether using a specific calming medicine (dexmedetomidine) for a longer period after a successful clot-removal procedure helps people do better in the long term. It may help improve outcomes after ischemic stroke where the clot is successfully treated.
Beijing, Beijing MunicipalityAges 18–80 - NCT05934669RecruitingPhase 4
Numbing medicines compared for small stitches in young children
This trial tests three medicines given through the nose to keep children comfortable during minor procedures in the emergency department, specifically for closing small cuts with stitches. It may help find which nasal medicine works best and is safest for quick, minimal procedures.
Oklahoma City, OklahomaAges 1–5 - NCT07799311RecruitingPhase 4
Medication to prevent waking distress after child hernia surgery
This trial tests two medicines to help children wake up calmly and comfortably after hernia surgery under anesthesia. It aims to find which one works better to reduce agitation or confusion when coming out of anesthesia.
Islamabad, FederalAges 2–12 - NCT07769255Recruiting
Nebulized dexmedetomidine for early chronic migraine
This trial tests whether a medicine called dexmedetomidine, given through a nebulizer (mist you breathe in), can help reduce the number of headache days and prevent migraines from becoming chronic. It is for people who have recently started having many headache days each month.
Banī SuwayfAges 18–55 - NCT07767383RecruitingPhase 4
Improving sleep quality after knee surgery with added sedation and nerve blocks
This trial tests whether adding a calming medicine called dexmedetomidine to a nerve block around the knee can help you sleep better after arthroscopic knee surgery. It aims to find if this combination reduces sleep problems during recovery.
Nantong, JiangsuAges 18–85 - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT04912518Recruiting
Dexmedetomidine for heart protection after a specific heart attack
This study tests whether dexmedetomidine can protect the heart in people who are having a specific type of heart attack (anterior STEMI) when treated within 6 hours of symptom start. You may be considered if your diagnosis and vital signs fit the study safety rules, and if you can take part in follow-up.
Hefei, AnhuiAges 18–75 - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT06641206Recruiting
Dexmedetomidine injection for chronic knee pain
This trial tests whether a single injection of dexmedetomidine into the knee joint can reduce chronic knee pain. It is for people who are not scheduled for knee surgery and have no serious health problems.
Tanta, El GharbyiaAges 40–75 - NCT07705022Enrolling by invitationPhase 2
Brain activity study during light sedation
This study uses brain scans (fMRI) to see if people who are lightly sedated can still think or respond. Researchers want to understand 'covert consciousness' during sedation with two common medicines, dexmedetomidine and ketamine.
Ann Arbor, MichiganAges 18–40 - NCT07676942Recruiting
Pain relief options after urethral surgery
This study compares two medications given during surgery to see which one better manages pain after urethral reconstruction. It aims to improve recovery and comfort after the procedure.
WarsawAges 18 years+ - NCT07677917Enrolling by invitationPhase 1
Medicine to reduce restlessness after sinus surgery
This trial tests two inhaled medicines, dexmedetomidine and magnesium sulfate, to see which is better at preventing agitation and restlessness as patients wake up from functional endoscopic sinus surgery. It may help you recover more calmly.
CairoAges 21–50 - NCT07669012RecruitingPhase 1
Sedation comparison for child heart hole repair
This study compares two sedation combinations (ketamine-propofol vs. dexmedetomidine-propofol) in children having a heart catheter procedure to close a simple hole or opening. The goal is to see which combination provides safer, more comfortable sedation.
CairoAges 2–12 - NCT06252662RecruitingPhase 4
Comparing two numbing medicines for mastectomy nerve blocks
This study compares two types of numbing medicine given through a nerve block before a mastectomy. One is a long-acting version (liposomal bupivacaine) and the other is a standard numbing medicine combined with a sedative (bupivacaine with dexmedetomidine). The goal is to see which provides better pain relief after surgery.
Portsmouth, VirginiaAges 18 years+ - NCT06702488RecruitingPhase 1
Dexmedetomidine and magnesium to protect thinking after surgery in seniors
This study tests whether adding two drugs, dexmedetomidine and magnesium sulfate, during anesthesia can help older adults keep their thinking and memory sharp after open abdominal surgery. It aims to reduce the risk of confusion or memory problems that sometimes happen after surgery.
Al FayyumAges 60–80 - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 178 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.