Treatment
Dexmedetomidine clinical trials
We’re tracking 178 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT06712186RecruitingPhase 1/Phase 2
Dexmedetomidine for safer intubation in high blood pressure patients
This study tests if dexmedetomidine can help prevent dangerous blood pressure spikes during breathing tube placement for surgery in patients with high blood pressure. It is for older adults (over 60) who have been managing their hypertension for at least 6 months.
Karachi, SindhAges 60 years+ - NCT07565116Recruiting
Numbing Nose Spray vs. Calming Liquid Before Pediatric Surgery
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
Diyarbakır, Outside of the USAges 2–10 - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT07550881RecruitingPhase 2
Intranasal Dexmedetomidine for Sudden Anxiety in Adults
This study tests whether a medication called dexmedetomidine, given as a nasal spray, can quickly relieve sudden anxiety. The goal is to see if this approach works better or faster than current treatments for acute anxiety episodes.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07532733Recruiting
Sedation Safety During Minimally Invasive Heart Valve Procedure
This study examines how a specific sedative medication (dexmedetomidine) affects breathing and heart function during a minimally invasive procedure to replace a faulty heart valve. Researchers want to ensure the sedation is safe and effective for older adults.
BrusselsAges 60 years+ - NCT07519863RecruitingPhase 2
Comparing sedation medicines for burned children during procedures
This study tests two different sedation medicine combinations to see which one reduces confusion and agitation (called delirium) when children with burn injuries need procedures done. The goal is to find the safest, most comfortable option for your child during treatment.
CairoAges 3–16 - NCT07523438Recruiting
Nasal Medication to Reduce Agitation After Eye Surgery in Young Children
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
AlexandriaAges 3–6 - NCT07502651Enrolling by invitationEarly Phase 1
Comparing two sedatives for jaw fracture surgery
This trial tests two medications given as a nasal spray to help you relax during surgery for a broken jaw. The goal is to see which one works better and is safer.
Rohtak, HaryanaAges 18–50 - NCT06759116Recruiting
Comparing two pain medicines for knee surgery recovery
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
El SharkiaAges 21–85 - NCT07462195RecruitingPhase 4
Dexmedetomidine for smoother recovery after thyroid surgery
This trial tests whether adding a medicine called dexmedetomidine during thyroid surgery helps you wake up more calmly and comfortably. It may reduce side effects like confusion or shakiness after anesthesia.
HanoiAges 18–65 - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT07427446RecruitingPhase 4
Calming drugs for children after heart catheterization
This trial compares two combinations of sedative medicines (dexmedetomidine with midazolam versus ketamine with midazolam) to see which better prevents confusion or agitation when a child wakes up after a heart catheterization procedure. It may help your child recover more calmly.
CairoAges 2–6 - NCT06778811RecruitingPhase 4
Sleep quality study for heart surgery patients
This trial studies sleep problems before and after heart surgery. It tests two medicines to see if they can help improve sleep. This may help you recover better after surgery.
Nanjing, JiangsuAges 40–75 - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT07386600Recruiting
Comparing two drugs for knee replacement pain relief
This trial tests two different drugs (dexamethasone and dexmedetomidine) added to a standard nerve block for knee replacement. It aims to see which one provides better pain control after surgery.
PoznanAges 65–100 - NCT07363681Recruiting
Comparing Two Anesthesia Methods for Urological Surgery
This study compares two types of anesthesia during urological surgery: inhaled gases versus a medicine called dexmedetomidine. The goal is to see which one helps you recover more smoothly in the recovery room.
Istanbul, IstanbulAges 39–99 - NCT07368062Recruiting
Mental health after a heart rhythm drug in the ICU
This study looks at the long-term mental health of people who received a drug called dexmedetomidine during an electrical storm (a dangerous heart rhythm) in the ICU.
Ottawa, OntarioAges Any age - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79 - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery
This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.
LjubljanaAges 6 months–3 years - NCT07327372Recruiting
Numbing with sedation for hip surgery in older adults
This trial tests a numbing injection (called a PENG block) plus a sedative (dexmedetomidine) for older adults having hip surgery. The goal is to see if this combination gives better pain relief and fewer side effects.
PoznanAges 65–100 - NCT07324057Recruiting
Medication before surgery to reduce autism-related anxiety in children
This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.
Nanjing, JiangsuAges 2–12 - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 178 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.