Treatment
Standard systemic therapy clinical trials
We’re tracking 318 recruiting studies that include Standard systemic therapy, each written for real people, not researchers, below.
Recruiting studies
- NCT03678025RecruitingPhase 3
Standard treatment for metastatic prostate cancer, with or without local treatment
This Phase 3 trial studies whether using the usual medicines for metastatic prostate cancer, plus a definitive local treatment to the prostate, improves outcomes. It may help determine if treating the prostate directly can benefit people whose cancer has not worsened after initial hormone-based treatment.
Gilbert, ArizonaAges 18 years+ - NCT07394257Recruiting
Antibiotic injection for hard-to-treat bacterial eye infection
This trial tests if an antibiotic injection directly into the cornea can help when standard eye drops are not working for a stubborn bacterial eye infection.
MinyaAges 20 years+ - NCT07105735RecruitingPhase 1
RN1201 injection for hard-to-treat autoimmune diseases
This study tests an investigational injection called RN1201 for people whose autoimmune disease (like lupus, myasthenia gravis, or immune thrombocytopenia) has not responded to standard therapies. The goal is to see if it can better control the disease.
Nanjing, JiangsuAges 18 years+ - NCT07685327Recruiting
Mixed reality vs. physical therapy for balance in teens with cerebral palsy
This study compares two types of therapy to help teens with spastic diplegic cerebral palsy improve their balance and coordination. One group will use mixed reality (a blend of real and virtual environments) and the other group will do standard physical therapy exercises.
Mansehra, KpkAges 10–19 - NCT04307576RecruitingPhase 3
Study for newly diagnosed ALL children and young adults
This Phase 3 trial studies a treatment plan for people up to age 45 who are newly diagnosed with B-cell or T-cell acute lymphoblastic leukemia (ALL). The goal is to see whether the study treatment improves outcomes compared with standard approaches.
BrusselsAges birth–45 years - NCT07019363RecruitingPhase 3
CDK4/6 inhibitor plus hormone therapy for high-risk breast cancer
This trial tests whether adding a CDK4/6 inhibitor (a type of targeted pill) to standard hormone therapy after surgery can lower the risk of breast cancer coming back in women with high-risk, hormone-receptor-positive, HER2-positive early breast cancer.
ShanghaiAges 18–70 - NCT06282575RecruitingPhase 3
Zanidatamab plus chemo for advanced HER2-positive bile duct cancer
This phase 3 trial tests whether adding zanidatamab (a targeted antibody) to standard chemotherapy can improve outcomes for advanced HER2-positive biliary tract cancer. If you have this type of cancer that has spread or can't be removed, and you've had little or no prior treatment, this study might be an option.
Duarte, CaliforniaAges 18 years+ - NCT05263570Recruiting
Real-world treatment planning for stage II–III HR+ HER2+ breast cancer
This trial looks at how well a standard “neoadjuvant” treatment plan works in real-world patients. It is for people newly diagnosed with stage II–III HR+ breast cancer and aims to see whether treatment gives expected outcomes in everyday care.
Shenyang, LiaoningAges 18 years+ - NCT07829848Recruiting
Skip extra radiation for breast cancer patients who respond well to treatment
This trial tests whether women and men with advanced, non-metastatic breast cancer can safely skip an extra radiation boost to the lymph nodes if their tumors respond well to pre-surgery chemotherapy or targeted therapy. The goal is to reduce side effects while keeping cancer control.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07291297RecruitingPhase 2
Metformin plus standard therapy for soft tissue sarcoma
This trial tests adding metformin, a common diabetes drug, to the usual first cancer treatment for advanced soft tissue sarcoma. It may help the standard therapy work better.
Charlotte, North CarolinaAges 18 years+ - NCT05534321RecruitingPhase 1/Phase 2
Preventive radiation for high-risk spinal bone metastases
This trial tests whether preventive (before serious problems happen) radiation to the spine can help people with high-risk, mostly symptom-free bone metastases. It may reduce the chance of pain escalation or dangerous complications from cancer in the spine.
Miami, FloridaAges 18 years+ - NCT06781060Recruiting
Nerve stimulation for sciatic nerve injury in children
This trial tests if electrical nerve stimulation can help children aged 3 to 19 who have nerve damage in the leg caused by an injection. The goal is to improve nerve healing and leg function.
Multan, Punjab ProvinceAges 3–19 - NCT07360808Recruiting
Fat Cell Therapy for Hand Problems in Scleroderma
This study tests whether a person's own fat cells (processed into regenerative cells) can be injected into the hands to improve hand function and reduce skin thickening in systemic sclerosis (scleroderma). It’s designed for people whose hand problems are significant but not too severe.
Guangzhou, GuangdongAges 18–70 - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Los Angeles, CaliforniaAges 18–75 - NCT06783335Recruiting
Cordella sensor for chronic heart failure
This trial studies a small sensor placed in the lung artery to help manage chronic heart failure. It compares patients who get the sensor to those who receive standard care, to see if the sensor improves outcomes.
Naperville, IllinoisAges 18 years+ - NCT05154253RecruitingPhase 1
Improving ankle push-off in children with cerebral palsy
This early (Phase 1) study tests a way to improve how well the ankle muscles help you push off when walking in cerebral palsy. If the ankle function improves, it may lead to a more comfortable and safer walking pattern.
Minneapolis, MinnesotaAges 8–21 - NCT07201519RecruitingPhase 2
Chemo infusion for liver cancer using a hybrid care model
This trial tests a special type of chemotherapy (hepatic artery infusion) for people with cancers that have spread to the liver, such as colorectal cancer or bile duct cancer (intrahepatic cholangiocarcinoma). It studies whether delivering this treatment partly at a community center and partly at a university hospital is safe and feasible.
Lexington, KentuckyAges 18–99 - NCT07855926Recruiting
Perioperative drug therapy for muscle-invasive bladder cancer
This study looks at different drug treatments given around the time of surgery for muscle-invasive bladder cancer. It aims to understand how well these treatments work and may help guide future care.
MunichAges 18 years+ - NCT06114108Recruiting
Adding local treatment to drug therapy for stage IV lung cancer
This trial compares continuing drug therapy alone versus adding local treatments (surgery or radiation) for people with stage IV lung cancer that has responded to initial treatment but still has a few remaining spots (oligometastatic). The goal is to see if targeting those spots with local therapy helps control the cancer longer.
AarauAges 18 years+ - NCT06927635RecruitingPhase 2
SBRT vs standard care for prostate cancer that has spread to a few spots
This trial tests whether targeted radiation (SBRT) to a few sites of cancer spread can help men whose prostate cancer has stopped responding to hormone therapy but has not spread to many places. You may benefit if you have a limited number of growing spots outside the brain or spine.
Toronto, OntarioAges 18–100 - NCT07250477RecruitingPhase 2
Guided immunotherapy for advanced lung cancer
This trial tests whether using a blood test to guide treatment can improve outcomes for people with advanced non-small cell lung cancer who are starting immunotherapy for the first time. Participants will receive standard immunotherapy tailored to their individual risk profile.
Chico, CaliforniaAges 18 years+ - NCT06924710Recruiting
Adaptive therapy for early stage lung cancer with no MRD detected
This study tests a new approach for people with early-stage non-small cell lung cancer (NSCLC) who have had their tumor completely removed. It uses regular blood tests (MRD monitoring) to watch for any cancer cells left behind, so treatment can be given only if needed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07193641RecruitingPhase 2
Lattice radiotherapy with standard care for slow-growing lung cancer
This trial tests whether adding a special radiotherapy technique called lattice radiotherapy to your usual cancer treatment can help control NSCLC that has started to grow in a few new spots. If you have up to 5 growing tumors and at least one measures 4.5 cm or larger, this study might be an option.
Hangzhou, ZhejiangAges 18 years+ - NCT06563479RecruitingPhase 3
Personalized vs. standard radiation for HPV-positive throat cancer
This trial compares a personalized, shorter course of radiation therapy to the standard longer course for people with HPV-positive throat cancer. The goal is to see if personalized treatment is just as effective while reducing side effects.
Hartford, ConnecticutAges 18 years+
Common questions
- Are there clinical trials studying Standard systemic therapy?
- Yes. Clin2 currently lists 318 recruiting studies that include Standard systemic therapy, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Standard systemic therapy trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Standard systemic therapy an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Standard systemic therapy or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.