Clinical trials
Ablation clinical trials
Below are recruiting ablation clinical trials, each written for real people, not researchers. We’re tracking 656 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06831136RecruitingPhase 2
Endoscopic ultrasound ablation with immunotherapy for pancreatic cancer
This trial tests a procedure that uses sound waves to heat and destroy part of the tumor, combined with an immunotherapy drug called pembrolizumab (Keytruda) that helps your immune system fight the cancer. It is for people with pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body.
Houston, TexasAges 18 years+ - NCT06833138Recruiting
Pacing vs medication for heart rate control in AF with heart failure
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
BesançonAges 18 years+ - NCT06801392Recruiting
Pulsed-field ablation for non-paroxysmal atrial fibrillation
This trial tests a new way to treat non-paroxysmal atrial fibrillation (AF) using a focused type of ablation (pulsed-field energy) on specific areas of the heart. It aims to see if targeting the left atrial wall and mitral isthmus can improve outcomes for people who have not had this procedure before.
PragueAges 18 years+ - NCT06796348Recruiting
Needle treatment vs surgery for small thyroid cancers
This study compares a non-surgical procedure (radiofrequency ablation) with partial thyroid removal (hemithyroidectomy) for treating small thyroid cancers. It aims to find out if the needle-based treatment is as effective as surgery, with fewer side effects.
AarhusAges 30 years+ - NCT06784466Recruiting
New ablation procedure for atrial fibrillation
This study is testing a new type of ablation procedure for atrial fibrillation (an irregular heart rhythm). It uses special energy to create scar tissue in the heart to block faulty electrical signals. If you have AF that isn’t controlled by medication, you may qualify.
Birmingham, AlabamaAges 18–80 - NCT06776588Recruiting
Microwave ablation with biopsy for ground-glass lung cancer
This trial tests a treatment that uses heat (microwave ablation) to destroy ground-glass lung nodules while also taking a tissue sample (biopsy) to confirm the diagnosis. It's for people whose lung nodules are 3 cm or smaller and who cannot or choose not to have surgery.
Harbin, HeilongjiangAges 18–75 - NCT05432024Recruiting
Heart MRI checks how well ablation lesions form
This study uses a special heart MRI to look at how ablation creates scar tissue in people with atrial fibrillation. It may help doctors improve how ablation is done and understand which technique works best.
NieuwegeinAges 18 years+ - NCT06732388RecruitingPhase 2
Itraconazole with ablation to prevent esophageal cancer in Barrett's esophagus
This trial tests if adding the antifungal drug itraconazole to standard ablation therapy can help prevent esophageal cancer in people with high-risk Barrett's esophagus. You must have a confirmed diagnosis of Barrett's esophagus with low- or high-grade dysplasia or early-stage cancer, and be planning to have ablation treatment.
Kansas City, KansasAges 18 years+ - NCT05953961Recruiting
90Y radiation compared with microwave ablation for small liver cancer
This trial compares two procedures to treat a small, single liver tumor that cannot be surgically removed. It aims to see which treatment works better for people with low blood protein (albumin), which can affect healing and outcomes.
New Orleans, LouisianaAges 18 years+ - NCT06705803Recruiting
Prostate cancer ablation registry study
This study collects information from men with prostate cancer who are having or have had a procedure to destroy prostate tumors (ablation). It aims to track outcomes over time to improve future treatments.
Hyde Park, IllinoisAges 22 years+ - NCT06712745RecruitingEarly Phase 1
Personalized lung cancer radiation therapy study
This trial tests a new approach to radiation therapy for central lung cancers, giving high doses in very short bursts to see if it's safe and effective. It may be an option for people whose tumors are not too large and are in a specific central location.
Dallas, TexasAges 18 years+ - NCT06699342Recruiting
Pacing and heart ablation for atrial fibrillation
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
Seoul, Jongno-guAges 65 years+ - NCT06689488Recruiting
Microwave ablation for lung cancer via bronchoscopy
This study tests a new, less invasive way to treat lung cancer using microwave energy delivered through a thin tube inserted into the airway. It is for people with small, confirmed lung tumors who are already being considered for surgery, and who cannot or prefer not to have blood thinners.
Amsterdam, The NetherlandsAges 18 years+ - NCT05337241Recruiting
Saline enhanced needle ablation for stubborn heart rhythm
This trial studies a special “needle” ablation method (with saline) to treat a dangerous, repeat heart rhythm problem called monomorphic ventricular tachycardia (VT). It’s for adults whose VT keeps coming back despite prior treatments and who may not benefit from another standard ablation.
Birmingham, AlabamaAges 18 years+ - NCT05643209Recruiting
Mapping and ablation to treat abnormal heart electrical signals
This study uses detailed 3D heart mapping to find where abnormal electrical activity starts in Brugada syndrome and then performs ablation (a targeted scar or block). It’s mainly for adults who have had concerning symptoms and already have an implanted defibrillator (ICD).
Cotignola, RavennaAges 18 years+ - NCT06620835RecruitingPhase 2
Optimizing local treatments for ALK-positive lung cancer on brigatinib
This trial is for people with advanced ALK-positive lung cancer who are already taking the targeted therapy brigatinib and have a few remaining spots of cancer. It tests whether adding local treatments (like surgery, focused radiation, or ablation) to the remaining spots can improve outcomes.
BrestAges 18 years+ - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT06563388RecruitingPhase 3
SABR for limited metastatic cancer (ID-COMET trial)
This study tests a precise radiation technique called SABR to treat cancer that has spread to a few spots. It aims to see if this approach can help control the cancer better than usual treatment, especially for lung, prostate, colorectal, or other solid tumors with limited spread.
Buffalo, New YorkAges 1 year+ - NCT06543173Recruiting
Preventive heart ablation with defibrillator in high-risk patients
This study tests if doing a special heart procedure (catheter ablation) at the same time as implanting a defibrillator (ICD) can prevent dangerous heart rhythms better than the ICD alone. It is for people with a very weak heart pump due to blocked arteries who are getting a first-time ICD.
Copenhagen, Region HAges 18 years+ - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT06503744Recruiting
Comparing two minimally invasive heat treatments for early lung cancer
This trial compares two types of radiofrequency ablation (a heat-based treatment) for early-stage lung cancer that is located in the outer parts of the lung. One approach uses a needle through the chest wall, the other uses a bronchoscope through the airways. The goal is to see which works better for people who cannot have surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06426563Recruiting
Comparing microwave vs radiofrequency for benign thyroid nodules
This study compares two heat-based treatments—microwave ablation (MWA) and radiofrequency ablation (RFA)—for shrinking benign thyroid nodules that are moderate in size. If you have a non-cancerous, solid nodule at least 2 cm wide, this trial may help you avoid surgery.
Hong Kong, Hong KongAges 18 years+ - NCT06392932Recruiting
Esophageal temperature monitoring during heart ablation
This study tests a new way to monitor the temperature in your esophagus during a standard heart ablation procedure for atrial fibrillation. The goal is to see if the new catheter (Q-DOT Micro) safely heats the heart tissue without harming the esophagus.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for ablation?
- Yes. Clin2 currently lists 656 recruiting ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.