Clinical trials
Acute Chest Syndrome clinical trials
Below are recruiting acute chest syndrome clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT06694311Recruiting
Testing CPAP and high-flow oxygen for ARDS
This study tests two types of breathing support—CPAP (a mask that pushes air into your lungs) and high-flow nasal oxygen (a special tube in your nose)—to see which works better for people with ARDS, a serious lung condition. It may help you breathe more easily without needing a breathing tube.
Barcelona, BarcelonaAges 18–80 - NCT06955143Recruiting
Blood study for acute coronary syndrome patients
This study examines blood samples from people with different types of coronary artery disease to understand the condition better. It may help doctors learn how to treat heart problems in the future.
Lishui, ZhejiangAges 18 years+ - NCT06928662RecruitingPhase 1/Phase 2
Chemo, radiation, and donor stem cell transplant for high-risk blood cancers
This trial tests a strong chemotherapy and radiation combo followed by a donor stem cell transplant for people with aggressive blood cancers (like AML or MDS) that haven't responded to earlier treatments or came back. It aims to help prevent the cancer from returning.
Seattle, WashingtonAges 18 years+ - NCT06818266RecruitingPhase 3
Tocilizumab for severe chest crisis in sickle cell disease
This trial tests if the drug tocilizumab can help treat acute chest syndrome, a serious lung complication of sickle cell disease. It is for people with sickle cell disease who are hospitalized and need oxygen or breathing support. The study compares tocilizumab to a placebo to see if it speeds up recovery.
ParisAges 2 years+ - NCT06513949RecruitingPhase 2
Testing IC14 for ARDS on a ventilator
This trial tests a new treatment called IC14 for people in the hospital on a breathing machine for ARDS (a severe lung injury). The study aims to see if IC14, which blocks a protein involved in inflammation, can help the lungs heal faster.
Seattle, WashingtonAges 18 years+ - NCT06128070RecruitingPhase 2
Preventing GVHD after stem cell transplant for leukemia
This trial tests adding ruxolitinib to standard drugs (tacrolimus and methotrexate) to prevent graft-versus-host disease in children and young adults undergoing a stem cell transplant for acute leukemia or myelodysplastic syndrome. The goal is to lower the risk of GVHD and improve transplant outcomes.
Duarte, CaliforniaAges 2–22 - NCT05640271RecruitingPhase 2
Tocilizumab for acute chest syndrome in sickle cell
This trial studies tocilizumab (a medicine that calms inflammation) to treat acute chest syndrome in people with sickle cell disease. It may help improve symptoms and recovery by targeting key immune signals involved in this complication.
Chicago, IllinoisAges 12 years+ - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT05472337RecruitingPhase 2
Colchicine trial for better heart artery reopening after ACS
This trial tests whether colchicine (a medicine commonly used for inflammation) can improve how well clogged heart arteries reopen after a short-term heart emergency called ACS. You may be eligible if you’re hospitalized with ACS and are planned for a coronary angiogram and possible angioplasty soon.
Santiago, Santiago MetropolitanAges 18 years+ - NCT02355457Recruiting
Blood marker study in new heart attack symptoms
This study looks at blood “biomarkers” (signals in blood tests) in people who arrive with symptoms that could be a heart attack. It may help doctors spot and manage acute heart problems sooner and more accurately.
HamburgAges 18 years+ - NCT07246265Recruiting
Morphine clearance study for sickle cell crisis in ICU
This study looks at how the body clears morphine in adults with sickle cell disease who are in the intensive care unit (ICU) for a pain crisis or acute chest syndrome and are receiving morphine through a patient-controlled analgesia (PCA) pump. The goal is to understand how kidney function affects morphine breakdown.
Tours, FranceAges 18 years+ - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT07395076Recruiting
Study of immune causes of acute respiratory distress
This trial looks at how the immune system might cause severe breathing problems (ARDS). It may help doctors understand what happens in the lungs during this condition and find better ways to treat it.
ParisAges 18 years+ - NCT06536543Recruiting
Lung imaging to check over-inflation in ARDS patients lying on their stomach
This trial uses a special lung imaging belt (EIT) to see if the lungs are over-inflated in patients with severe breathing problems (ARDS) when they lie on their stomach. It aims to help doctors adjust ventilator settings for better lung protection.
BayonneAges 18 years+ - NCT06066502RecruitingPhase 3
Precision ventilation for ARDS
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
Tucson, ArizonaAges 18 years+ - NCT07317050RecruitingPhase 3
Aprotinin for acute respiratory distress syndrome
This trial tests a drug called aprotinin for people with moderate to severe ARDS who are on a breathing machine. The goal is to see if it helps treat the lung injury.
Ciudad Real, Ciudad RealAges 18 years+ - NCT05896826Recruiting
Magnetocardiography to better spot heart attack patients
This study tests whether magnetocardiography—a scan that measures heart signals using magnets—can more accurately identify myocardial infarction (heart attack). It may help doctors detect heart attacks faster and more accurately using safer, non-invasive testing.
Jinan, ShandongAges 18–79 - NCT07090460Recruiting
Measuring lung overstretch in prone-position ARDS patients
This study uses a special imaging belt (EIT) to check if the lungs are being overstretched when patients with severe breathing problems are placed on their stomach (prone position). It may help doctors adjust breathing machines more safely.
Bayonne, Centre Hospitalier de La Côte BasqueAges 18 years+ - NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75 - NCT05816954Recruiting
Imaging test to predict lung injury risk in ARDS
This study looks at scan images to better predict the risk of a serious lung complication (barotrauma) in people with ARDS. It may help doctors choose safer treatment strategies in the ICU.
Catanzaro, CalabriaAges 18 years+ - NCT06384846Recruiting
AI predicts heart attacks using white blood cells
This study tests whether an artificial intelligence tool can accurately predict a heart attack (acute coronary syndrome) by looking at the properties of your white blood cells. If successful, it could help doctors diagnose heart attacks faster from a simple blood sample.
Graz, Styria / SteiermarkAges 18 years+
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Common questions
- Are there clinical trials for acute chest syndrome?
- Yes. Clin2 currently lists 65 recruiting acute chest syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute chest syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute chest syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.