Clinical trials
Acute Kidney Disease clinical trials
Below are recruiting acute kidney disease clinical trials, each written for real people, not researchers. We’re tracking 305 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07030179Recruiting
Frailty, kidney injury, and blood pressure in non-cardiac surgery
This study looks at whether a patient's level of frailty (overall weakness and health before surgery) affects their risk of acute kidney injury after non-cardiac surgery, and whether blood pressure changes during surgery play a role in that link.
Nanjing, JiangsuAges 18 years+ - NCT07021157RecruitingPhase 1
First-in-human study of SK-08 in healthy volunteers
This trial tests a new drug called SK-08 in healthy volunteers to see if it's safe and how the body processes it. It helps doctors find the right dose for future studies of this potential medicine.
Hangzhou, ZhejiangAges 18–45 - NCT07017933Recruiting
Kidney support device for heart surgery patients
This trial tests a new device that helps support kidney function during heart surgery. It is for people with mild to moderate kidney problems who are having bypass or valve surgery.
Weston, FloridaAges 22–85 - NCT06174610Recruiting
Kidney ultrasound for ICU patients on dialysis
This study looks at how kidney ultrasound can help monitor critically ill patients who need continuous dialysis for acute kidney injury. The results may help doctors better manage treatment.
Opole, Opole VoivodeshipAges 18 years+ - NCT06431919Recruiting
Adding statin to carvedilol for cirrhosis with heart problems
This trial tests whether adding a statin (simvastatin) to the usual heart medication carvedilol helps people with both cirrhosis and a related heart problem live longer and avoid serious liver complications.
ChandigarhAges 18–65 - NCT04968587Recruiting
Compare two ways to clean blood during dialysis
This study compares two methods for removing waste products from the blood in people who need dialysis. It aims to see whether one method works better or is safer during extra-renal (outside the body) blood purification.
MelunAges 18 years+ - NCT06962098RecruitingPhase 2
Study of isuzinaxib for diabetic kidney disease
This trial tests an investigational drug called isuzinaxib (APX-115) for people with type 2 diabetes and diabetic kidney disease (DKD). The goal is to see if it can help protect kidney function. Participants must have stable kidney lab values and be on certain blood pressure or diabetes medications.
Ansan-siAges 19 years+ - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06696235RecruitingPhase 4
Comparing fast vs standard kidney therapy for heart shock patients on ECMO
This trial tests whether starting kidney replacement therapy faster or at the usual time improves outcomes for people with severe heart failure (cardiogenic shock) who are on a heart-lung machine (ECMO) and develop sudden kidney injury.
SeoulAges 19 years+ - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT06578533RecruitingPhase 3
Keeping heart and kidney medications while controlling potassium
This trial tests a medication (SZC) that helps lower high potassium levels, so you can keep taking important heart and kidney drugs (RAASi/MRA). It is for people with heart failure and chronic kidney disease who have high potassium.
AlicanteAges 18 years+ - NCT06446739Recruiting
Low-dose vs standard-dose kidney therapy for ICU patients
This study compares two different doses of continuous kidney replacement therapy (CRRT, a type of dialysis) for patients in the intensive care unit with acute kidney injury. It aims to find out if a lower dose is as safe and effective as the standard dose.
Rochester, MinnesotaAges 18 years+ - NCT05988658Recruiting
Using scores and biomarkers to predict kidney injury in hospital patients
This study uses a risk score and blood tests to predict which hospitalized patients might develop acute kidney injury (sudden kidney damage). If you are at high risk, researchers will follow you closely to see if early detection can help prevent serious kidney problems.
Chicago, IllinoisAges 18 years+ - NCT04144894Recruiting
Kidney ultrasound and health measurements for people without diabetes or high blood pressure
This trial looks at how well a “kidney ultrasound index” (a measurement from an ultrasound and health factors) can reflect kidney health. It may help researchers better understand which people are most likely to stay healthy and who may be at risk.
Birmingham, AlabamaAges 19 years+ - NCT06369064Recruiting
Comparing dialysis methods for kidney injury in the ICU
This trial compares two types of dialysis (hemodialysis and hemodiafiltration) to see which is better at removing waste from the blood in ICU patients with sudden kidney failure. It may help doctors choose the best treatment for you.
NîmesAges 18 years+ - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT06310967RecruitingPhase 1/Phase 2
Study of IG3018 for high uric acid with or without kidney disease
This trial tests a new medicine, IG3018, to lower high uric acid levels in people with or without chronic kidney disease. It aims to find the right dose and see if it's safe.
Botany, New South WalesAges 18–75 - NCT03329313RecruitingPhase 2
Adjusting dialysis salt levels for ICU kidney injury
This study tests whether using a specific salt (sodium) level in the dialysis fluid affects outcomes for adults in the ICU with sudden kidney failure. It may help your care team optimize dialysis settings during acute kidney injury.
Montpellier, MontpellierAges 18–80 - NCT06179771Recruiting
Filter during dialysis or ECMO for severe illness
This study tests a special filter (HA380 column) used during dialysis or ECMO to remove harmful substances from the blood. It is for critically ill patients with severe infection, injury, or breathing problems who also need kidney or lung support.
Leicester, LeicestershireAges 18–65 - NCT05836922Recruiting
Checking kidney oxygen after lung transplant to predict kidney injury
This pilot study looks at whether a painless skin sensor can measure kidney oxygen levels after lung transplant surgery. The goal is to predict and possibly prevent postoperative kidney failure by identifying risk early.
MarseilleAges 18 years+ - NCT05805709Recruiting
COPE-AKI: A care plan for people hospitalized with serious AKI
This trial tests a patient-centered plan for how care is organized and communicated for people hospitalized with serious, persistent kidney injury (AKI). The goal is to improve the experience and possibly outcomes by making care more consistent and easier to follow.
Birmingham, AlabamaAges 18 years+ - NCT04936607Recruiting
Protecting kidney health after heart angiograms or stents
This study looks at ways to improve kidney outcomes after a coronary angiogram and/or stent procedure. If you’re having one of these heart procedures and your kidneys aren’t already severely affected, the study may help reduce the risk of kidney worsening around the time of the procedure.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for acute kidney disease?
- Yes. Clin2 currently lists 305 recruiting acute kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.