Clinical trials
Acute Kidney Disease clinical trials
Below are recruiting acute kidney disease clinical trials, each written for real people, not researchers. We’re tracking 319 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06446739Recruiting
Low-dose vs standard-dose kidney therapy for ICU patients
This study compares two different doses of continuous kidney replacement therapy (CRRT, a type of dialysis) for patients in the intensive care unit with acute kidney injury. It aims to find out if a lower dose is as safe and effective as the standard dose.
Rochester, MinnesotaAges 18 years+ - NCT06524622Recruiting
Ultrasound and pressure test for sepsis in the ICU
This study tests whether a special ultrasound exam (VExUS) combined with a standard pressure measurement (CVP) can better predict outcomes for people with sepsis in the ICU. The goal is to see if these tools help doctors make better treatment decisions.
Yibin, SichuanAges 18–100 - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06578533RecruitingPhase 3
Keeping heart and kidney medications while controlling potassium
This trial tests a medication (SZC) that helps lower high potassium levels, so you can keep taking important heart and kidney drugs (RAASi/MRA). It is for people with heart failure and chronic kidney disease who have high potassium.
AlicanteAges 18 years+ - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06696235RecruitingPhase 4
Comparing fast vs standard kidney therapy for heart shock patients on ECMO
This trial tests whether starting kidney replacement therapy faster or at the usual time improves outcomes for people with severe heart failure (cardiogenic shock) who are on a heart-lung machine (ECMO) and develop sudden kidney injury.
SeoulAges 19 years+ - NCT05805709Recruiting
COPE-AKI: A care plan for people hospitalized with serious AKI
This trial tests a patient-centered plan for how care is organized and communicated for people hospitalized with serious, persistent kidney injury (AKI). The goal is to improve the experience and possibly outcomes by making care more consistent and easier to follow.
Birmingham, AlabamaAges 18 years+ - NCT06714214Recruiting
Predicting when you can stop kidney dialysis
This trial studies whether a blood test called delta C-cistatin can help doctors predict when patients can safely stop continuous kidney dialysis after acute kidney injury.
BolognaAges 18 years+ - NCT06753409Recruiting
Brain monitoring during anesthesia for major abdominal surgery
This study tests whether using a special brain wave monitor during anesthesia can improve recovery for people having major abdominal surgery lasting more than two hours.
AsyutAges 18–70 - NCT06835816Recruiting
Amino acid supplements during dialysis
This trial tests whether adding amino acid supplements during dialysis helps people with kidney failure. It may be an option if your doctor decides you need these supplements.
StockholmAges 18 years+ - NCT06867471Recruiting
Ketone drink study for kidney disease patients
This study tests if a ketone supplement can reduce protein in urine and protect kidney function in people with chronic kidney disease or polycystic kidney disease. You drink a special supplement and researchers measure how it affects your kidneys.
Herning, JutlandAges 18 years+ - NCT06886282Recruiting
How colon cancer and kidney disease are linked: a imaging and gene study
This trial uses advanced imaging and genetic tests to understand how colon cancer and chronic kidney disease may be connected. It may help decide the best treatment for people with both conditions.
NaplesAges 18 years+ - NCT06917859RecruitingPhase 1
Steroid to protect kidneys during heart surgery
This trial is testing whether a single dose of the steroid methylprednisolone, given before heart surgery, can protect your kidneys from damage during the operation. If you qualify, you'll receive the drug or a placebo, and your kidney function will be monitored closely.
Cairo, AbbasiaAges 18–65 - NCT06929169RecruitingPhase 2
SGLT2 inhibitor heart health study in dialysis patients
This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug also used for heart failure) affects the heart and blood vessels in people with kidney failure who are on dialysis. It will help doctors understand if this medicine is safe and helpful for dialysis patients.
Buenos Aires, Buenos AiresAges 18–70 - NCT06962098RecruitingPhase 2
Study of isuzinaxib for diabetic kidney disease
This trial tests an investigational drug called isuzinaxib (APX-115) for people with type 2 diabetes and diabetic kidney disease (DKD). The goal is to see if it can help protect kidney function. Participants must have stable kidney lab values and be on certain blood pressure or diabetes medications.
Ansan-siAges 19 years+ - NCT07017933Recruiting
Kidney support device for heart surgery patients
This trial tests a new device that helps support kidney function during heart surgery. It is for people with mild to moderate kidney problems who are having bypass or valve surgery.
Weston, FloridaAges 22–85 - NCT07021157RecruitingPhase 1
First-in-human study of SK-08 in healthy volunteers
This trial tests a new drug called SK-08 in healthy volunteers to see if it's safe and how the body processes it. It helps doctors find the right dose for future studies of this potential medicine.
Hangzhou, ZhejiangAges 18–45 - NCT07029503RecruitingPhase 2
Heart failure and kidney function study
This trial tests a new treatment for people with heart failure and severely reduced kidney function. It aims to see if the treatment can help protect both the heart and kidneys.
StockholmAges 18 years+ - NCT07047547Recruiting
Vericiguat study for kidney disease and heart failure patients
This trial tests how a medication called vericiguat works in people with both chronic kidney disease and heart failure. It aims to see if the drug helps manage these conditions together.
Guangzhou, GuangdongAges 18–80 - NCT07123181Recruiting
Oregano and basil for unstable angina
This trial tests if eating oregano and basil leaves can help people with unstable angina, a type of chest pain from heart disease. It looks for improvements in heart health without using strong medications.
Tehran, Tehran ProvinceAges 30–75 - NCT07134335RecruitingPhase 2
Study of UBT251 injection for chronic kidney disease
This study tests an investigational injection called UBT251 for people with chronic kidney disease who are overweight. It aims to see if it can reduce protein in the urine and help protect kidney function.
BeijingAges 18–75
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Common questions
- Are there clinical trials for acute kidney disease?
- Yes. Clin2 currently lists 319 recruiting acute kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.