Clinical trials
Amyotrophic Lateral Sclerosis clinical trials
Below are recruiting amyotrophic lateral sclerosis clinical trials, each written for real people, not researchers. We’re tracking 190 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07334743Recruiting
A study to find biomarkers in ALS using tiny brain particles
This trial collects blood and spinal fluid samples from people being checked for ALS. The goal is to find clues (biomarkers) in tiny particles from nerve cells that could help doctors better understand and diagnose ALS.
ParisAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07380204Recruiting
Measuring Hsp90 in the brain with a PET scan
This study uses a special PET scan to measure a protein called Hsp90 in the brain. It aims to understand how Hsp90 levels differ in healthy people and those with Parkinson's, Alzheimer's, or ALS, which may lead to new treatments.
Leuven, Vlaam-BrabantAges 18–70 - NCT00136500Recruiting
Research study for people with ALS and family risk
This study looks at people affected by ALS (a nerve disease) and, in some cases, family members who may be at genetic risk. It may help researchers better understand ALS and related conditions and improve how they’re studied.
Miami, FloridaAges 18 years+ - NCT00912041Recruiting
Test of a brain-to-computer device for quadriplegia
This study tests whether a tiny brain computer interface can help people with quadriplegia (loss of movement in all four limbs) communicate or control technology. It’s mainly a feasibility study, meaning the goal is to see if the device can work safely and reliably in real life.
Sacramento, CaliforniaAges 18–80 - NCT00801333Recruiting
Create patient-specific stem cells for research
This study uses adult body cells (from participants) to create special lab cells called stem cells for research. It’s mainly about whether cells can be made and studied, not about treating a disease.
JerusalemAges 18 years+ - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT07407725Recruiting
Study of brain-computer interface use in ALS, spinal cord injury, and healthy adults
This study tests how well people with ALS, spinal cord injury, or healthy volunteers can use a brain-computer interface (BCI). The goal is to learn how to measure what the device can do, which may help people with severe communication or movement limitations.
Chicago, IllinoisAges 18 years+ - NCT07467187Recruiting
Home Ventilation with Tracheostomy in Denmark (2016–2025)
This study looks at people in Denmark who need a home ventilator through a tracheostomy. It aims to understand their care and outcomes over several years.
CopenhagenAges Any age - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07533903Recruiting
Brain-Computer Interface for Arm Control in Paralysis
This trial tests a surgically implanted brain-computer interface (BCI) device designed to help people with severe arm paralysis—from conditions like ALS or stroke—regain some ability to control their arms. The device reads signals from your brain and translates them into arm movements, potentially helping you perform daily activities.
MelbourneAges 21 years+ - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07298486Enrolling by invitation
Robotic glove to help with grip and hand function in ALS
This trial tests whether a robotic glove can improve quality of life, grip strength, and fine motor control in people with ALS. If you have trouble with hand strength or dexterity, this device may help you regain some function.
Davie, FloridaAges 18–99 - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT06841341Enrolling by invitation
Predicting breathing problems in ALS
This study uses ultrasound and electrical tests of breathing muscles and nerves to see if they can predict breathing failure in people with ALS. This could help doctors know when a patient might need breathing support.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT06782958Enrolling by invitationPhase 1
Safety study of FHND1002 granules in healthy adults
This trial tests a new medication called FHND1002 in healthy adults aged 18 to 45. The goal is to check its safety, how well the body tolerates it, and how it is processed. It is one of the first tests in humans.
Lanzhou, GansuAges 18–45 - NCT06710626Enrolling by invitation
Using brain implants to control assistive devices
This trial looks at how well people who already have a Neuralink N1 brain implant can use it to control assistive devices like computers or wheelchairs. It's only for people already in the PRIME Study who meet certain safety and performance checks.
Phoenix, ArizonaAges Any age - NCT06605612Enrolling by invitation
Falls risk test for people with muscle and nerve conditions
This study is creating a test to predict falls in people with neuromuscular disorders. You will fill out a questionnaire about your fall risk.
München, BavariaAges 18–65 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT04961450Enrolling by invitation
Study tracking brain illness markers in motor neuron and frontotemporal disease
This study looks for “biomarkers” (measurable signs in blood or other samples) in people with motor neuron disease and frontotemporal dementia spectrum conditions. It also compares those findings with matched caregivers, to understand what might be happening in these diseases.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for amyotrophic lateral sclerosis?
- Yes. Clin2 currently lists 190 recruiting amyotrophic lateral sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a amyotrophic lateral sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.