Clinical trials
Anterior Cruciate Ligament (ACL) Reconstruction clinical trials
Below are recruiting anterior cruciate ligament (acl) reconstruction clinical trials, each written for real people, not researchers. We’re tracking 115 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07569796Recruiting
Nerve Stimulation to Help Recover After ACL Surgery
This study tests whether stimulating your sciatic nerve (a major nerve in your leg) can help you recover better after ACL reconstruction surgery. The goal is to reduce pain and help you regain strength and movement.
Madrid, MadridAges 18–60 - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT07475351Recruiting
Comparing two grafts for ACL reconstruction
This trial compares two types of grafts to rebuild the ACL in the knee, to see if one leads to better results. It is for active athletes with a recent ACL tear and healthy knees.
Granada, GranadaAges 12–40 - NCT04770233Recruiting
Comparing early surgery options for torn ACL
This study looks at the best way to treat a fresh ACL (an important knee ligament) tear by comparing an “early surgery” plan that starts within 12 weeks. It may help guide care and recovery for people who are able to do both the surgery and the follow-up rehabilitation.
Lørenskog, AkershusAges 16–50 - NCT06190223Recruiting
ACL repair using kneecap tendon with press-fit method
This study looks at a specific ACL reconstruction technique using a graft from your kneecap tendon that is fixed with a press-fit method. It aims to determine how well patients recover after at least one year.
AnkaraAges 18–55 - NCT05972876Recruiting
Blood-flow restriction rehab after ACL surgery
This trial looks at how well your ACL graft (the repaired tissue) heals after ACL reconstruction when you use a specific rehab method called blood-flow restriction training. It may help your care team understand whether this rehab approach leads to better healing and function.
Sittard, LimburgAges 18–65 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07404046Recruiting
Comparing tendon grafts for ACL surgery
This trial compares two types of grafts using the semitendinosus tendon for ACL reconstruction. It aims to see if adding a part of the tendon's muscle improves healing and stability after surgery.
ZagrebAges 18–50 - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT06259968Recruiting
Electrical stimulation after ACL surgery recovery trial
This trial tests if adding electrical stimulation to standard physical therapy helps people recover strength and movement after ACL reconstruction surgery. It compares two rehab programs starting within days after surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT07243535Recruiting
Rhythm training for athletes after ACL surgery
This study compares two types of rhythm-based training (fractal vs isochronous cueing) to see which helps athletes regain better movement after ACL reconstruction. If you're an athlete who had ACL surgery less than two years ago and are now pain-free walking, you may be able to join.
Almada, Monte de CaparicaAges 15–35 - NCT06505525Recruiting
ACL reconstruction: adding extra support vs standard surgery
This trial compares two surgical techniques for ACL reconstruction. The standard method repairs the ACL inside the knee joint, while the new method also adds extra support outside the joint. The study aims to see which approach gives better stability and recovery for people with specific risk factors, like being a young athlete or having a chronic ACL tear.
São Paulo, São PauloAges 14–40 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT07201597Recruiting
Readiness and knee function after ACL surgery
This study looks at how your mental readiness, knee function, and strength relate after ACL reconstruction using a specific type of tendon graft. It may help you understand if you're ready to return to sports.
Cairo, Cairo GovernorateAges 18–35 - NCT06905691Recruiting
Eccentric training after ACL reconstruction
This study tests if a specific exercise (eccentric training) helps people recover better after ACL surgery. You may join if you are between 18 and 40 and are scheduled for this surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT07185802Recruiting
PRP injection for recent ACL injury
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
DhakaAges 18–50 - NCT06955026Recruiting
Hockey slideboard and blood flow restriction for ACL rehab
This trial tests if using a hockey slideboard with blood flow restriction (a special band that limits blood flow during exercise) helps recovery after ACL surgery. It may improve muscle strength and function faster.
Odorheiu Secuiesc, RomaniaAges 18–45 - NCT07134244Recruiting
Predicting cartilage damage and pain after knee injury or early arthritis
This study uses computer models and MRI scans to predict how knee cartilage and pain may change over time in people with early osteoarthritis or a recent ACL tear. It aims to find better ways to manage these conditions and prevent long-term damage.
Aalborg, North DenmarkAges 18–70 - NCT07128602Recruiting
Brain stimulation to help quadriceps after ACL surgery
This study tests whether a gentle, non-invasive brain stimulation can improve thigh muscle function in women recovering from ACL reconstruction. If you are between 2 and 6 months post-surgery, you may be able to join.
Glenside, PennsylvaniaAges 18–35 - NCT07097077Recruiting
Brain changes after ACL surgery with special training
This study uses brain scans (fMRI) to see how a special type of movement training affects the brain after ACL surgery. If you've had an ACL repair and are active in sports, you may be eligible.
Bologna, BolognaAges 18–30
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Common questions
- Are there clinical trials for anterior cruciate ligament (acl) reconstruction?
- Yes. Clin2 currently lists 115 recruiting anterior cruciate ligament (acl) reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament (acl) reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament (acl) reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.