Clinical trials
Anterior Cruciate Ligament Injuries clinical trials
Below are recruiting anterior cruciate ligament injuries clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04770233Recruiting
Comparing early surgery options for torn ACL
This study looks at the best way to treat a fresh ACL (an important knee ligament) tear by comparing an “early surgery” plan that starts within 12 weeks. It may help guide care and recovery for people who are able to do both the surgery and the follow-up rehabilitation.
Lørenskog, AkershusAges 16–50 - NCT04650568Enrolling by invitation
Stem cell treatment after ACL ligament surgery
This trial studies whether adding mesenchymal stem cells during ACL (knee ligament) reconstruction helps the knee heal better. You might be eligible if your ACL injury is recent and you’re having a specific type of graft surgery.
Chicago, IllinoisAges 18–60 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT04183803Recruiting
Robot help to set the right position for ACL surgery
This study tests whether using a robot to help place the tunnel during ACL (knee ligament) reconstruction is better or more accurate than the usual approach. You may benefit if you need ACL surgery and your care team has robot experience.
AmiensAges 10 years+ - NCT07333092Recruiting
Balance exercises after ACL surgery
This trial tests whether special balance and movement exercises (proprioceptive exercises) help people recover better after ACL knee surgery. You would start these exercises during the second week of your rehab program.
SanliurfaAges 20–40 - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35 - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65 - NCT02771548Recruiting
Strength and movement study after ACL knee surgery
This study looks at how your knee moves during daily-style tasks and how strong your muscles are after ACL surgery. It may help researchers understand recovery and improvement after reconstruction.
Dublin, LeinsterAges 13–45 - NCT07501013Recruiting
Shoulder and knee surgery outcomes study
This study looks at how well different types of shoulder and knee surgeries work for sports injuries. It aims to help improve future care by following patients' recovery after common procedures like fixing torn cartilage or repairing ligaments.
Hangzhou, ZhejiangAges 8–80 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT06635668Recruiting
ACL injury risk screening study for athletes
This study screens healthy athletes aged 10 to 65 to understand what normal ACL injury risk looks like. It helps set a baseline so doctors can better identify those at higher risk.
Fargo, North DakotaAges 10–65 - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT06956339Recruiting
Bracing vs Surgery for First-Time ACL Tear
This trial compares a new bracing treatment (Cross Bracing Protocol) versus standard surgery for people who have torn their ACL for the first time. It aims to see which approach leads to better recovery and fewer complications.
Melbourne, VictoriaAges 16–40 - NCT06762392Recruiting
Blood flow restriction for ACL rehab: a pilot study
This study tests whether using a special band that slightly restricts blood flow (blood flow restriction) during rehabilitation can help people recover better after ACL knee surgery. It's a small early study to see if this method is safe and effective.
Valencia, ValenciaAges 18 years+ - NCT07671729Recruiting
Comparing two tendon grafts for ACL surgery
This study compares two types of tendon grafts (from your kneecap tendon or from a tendon in your leg) for ACL reconstruction. The goal is to see which one works better for getting you back to normal activity.
Istanbul, BesiktasAges 18–50 - NCT07485530Recruiting
Testing ultrasound strain tracking for physical therapy
This trial tests whether a new ultrasound method (speckle tracking) can measure soft tissue movement and strain to help guide physical therapy. It is looking for three groups: male pitchers, people with a foot tendon problem needing surgery, and people who had ACL knee surgery.
TaipeiAges 18–65 - NCT07411625Recruiting
Pre-surgery exercise program for ACL injury patients
This trial tests whether doing special exercises before ACL surgery (called prehabilitation) helps you recover better after the operation. It's for people who have a first-time ACL tear and are scheduled for reconstruction surgery using a tendon from their own body.
NantesAges 18 years+ - NCT07475351Recruiting
Comparing two grafts for ACL reconstruction
This trial compares two types of grafts to rebuild the ACL in the knee, to see if one leads to better results. It is for active athletes with a recent ACL tear and healthy knees.
Granada, GranadaAges 12–40 - NCT06942754Recruiting
Bracing vs. surgery for ACL tears
This study compares two ways to treat a torn ACL: bracing alone or surgery using your own quadriceps tendon. It aims to find which option helps you return to sports best.
Winston-Salem, North CarolinaAges 14–39 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT07862868Recruiting
Comparing two knee rehab exercises after ACL surgery
This study compares two different exercise programs to help people recover knee strength and function after ACL reconstruction surgery. One program uses steady machine-based exercises, while the other uses jumping and quick movements. The goal is to find which approach works better for getting you back to normal activities.
Qina, Qena GovernorateAges 18–40
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Common questions
- Are there clinical trials for anterior cruciate ligament injuries?
- Yes. Clin2 currently lists 112 recruiting anterior cruciate ligament injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.