Clinical trials
Aortic Valve Stenosis clinical trials
Below are recruiting aortic valve stenosis clinical trials, each written for real people, not researchers. We’re tracking 217 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07276711Recruiting
Protecting brain during TAVR with EmStop device
This trial tests a new device (EmStop) that helps protect your brain during TAVR (a type of heart valve replacement). The device is placed in arteries to catch any debris that might break loose during the procedure, potentially reducing the risk of stroke.
New Orleans, LouisianaAges 22 years+ - NCT07278310Recruiting
Siegel Valve for Severe Aortic Stenosis (TAVR)
This study tests a new replacement valve called the Siegel, placed through a catheter in your leg (TAVR), for people with severe aortic stenosis. It aims to see if it is safe and effective for patients at low, intermediate, or high surgical risk.
Atlanta, GeorgiaAges 18 years+ - NCT07284550Recruiting
Smartphone screening for aortic valve stenosis
This study tests if a smartphone app can detect aortic valve stenosis (a heart valve condition) by recording heart sounds. If successful, it could offer a simple, non-invasive way to screen for this condition without a doctor's visit.
InnsbruckAges 18 years+ - NCT07335900Recruiting
Studying heart healing after TAVI with FAPI-PET scan
This study uses a special type of PET scan (FAPI-PET) to see how the heart heals after a less invasive valve replacement procedure called TAVI. It aims to help doctors better understand the changes in heart tissue after treatment for aortic stenosis.
ShanghaiAges 18 years+ - NCT07370688RecruitingPhase 4
Iron infusion after TAVI for older adults
This trial tests whether giving iron infusions after a TAVI procedure can help patients with iron deficiency feel better and improve their quality of life. It is for older adults who have low iron levels and have already had a successful valve replacement.
Rotterdam, South HollandAges 65 years+ - NCT01805739Recruiting
Imaging tests for people before aortic valve replacement
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT01737528Recruiting
Transcatheter heart valve therapy registry for adults
This registry collects information from adults who receive a less invasive heart valve procedure (done through a catheter). The goal is to learn how these treatments work in real-world patients and care over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02448485Recruiting
Measuring Troponin T blood levels in aortic valve narrowing
This study looks at a blood test called high-sensitivity troponin T in people with aortic stenosis (a narrowed heart valve). The results may help doctors understand heart strain or risk in this condition.
Innsbruck, TyrolAges Any age - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT02023060Recruiting
Improving function and quality of life after heart valve repair
This study looks at how a less invasive heart valve procedure affects your day-to-day functioning and overall quality of life. If you’re already being considered for a transcatheter (catheter-based) valve replacement, you may be able to join to help understand what improvements patients experience.
JerusalemAges 18–110 - NCT07414342Recruiting
Study of RENATUS® valve for severe aortic stenosis
This study tests a new device called the RENATUS® Transcatheter Aortic Valve System for people with severe aortic stenosis. It is designed to replace the narrowed valve without open-heart surgery, and aims to see if it is safe and effective for patients with various surgical risk levels.
BeijingAges 60–100 - NCT07455292Recruiting
Heart valve study using advanced MRI
This study uses a special type of MRI, called 4D flow MRI, to better understand how severe aortic stenosis (a narrowed heart valve) affects heart function. It may help doctors learn more about different types of this condition and improve future treatment.
San Donato MilaneseAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT05672836RecruitingPhase 4
Enavogliflozin after TAVR for heart narrowing with mild heart weakness
This trial tests enavogliflozin (a diabetes medication that may help the heart) in people who have had a TAVR procedure for severe aortic stenosis. It looks at whether the medicine can improve outcomes for people with symptoms and mildly reduced or preserved pumping function.
Bucheon-siAges 19 years+ - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+ - NCT07258706Enrolling by invitation
Study on TAVI results based on patient differences
This trial is for people with severe aortic stenosis who are already scheduled for TAVI (a procedure to replace a narrowed heart valve). It looks at how individual differences affect the procedure's outcomes.
VicenzaAges 18 years+ - NCT07045233Enrolling by invitation
Using a brain protection device during TAVR to prevent stroke
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
BeijingAges 18 years+ - NCT06753227Enrolling by invitation
Comparing ways to measure valve pressure after TAVI
This trial looks at how well a new method (using echo) compares to the standard invasive method for measuring pressure across the new valve after TAVI. It may help doctors monitor your valve function with less risk.
Munich, BavariaAges 18 years+ - NCT06679517Enrolling by invitation
Long-term follow-up for severe aortic stenosis patients considered for TAVI
This study follows patients with severe aortic stenosis (a heart valve condition) who are being evaluated for a keyhole procedure called TAVI. It aims to understand their long-term outcomes after the standard evaluation process.
FerraraAges 18 years+ - NCT06597188Enrolling by invitation
TAVR vs. Surgery for severe bicuspid aortic valve stenosis
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
Chengdu, SichuanAges 18–75 - NCT06571175Enrolling by invitation
Measuring heart scarring in aortic stenosis patients
This study uses imaging to measure heart scarring in people with aortic stenosis, a condition where the heart valve is narrowed. It aims to better understand how scarring affects long-term outcomes.
Trondheim, TrøndelagAges 18–90
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Common questions
- Are there clinical trials for aortic valve stenosis?
- Yes. Clin2 currently lists 217 recruiting aortic valve stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic valve stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic valve stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.