Clinical trials
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION clinical trials
Below are recruiting atrial appendage closure for atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07036965Recruiting
Comparing two types of ablation catheters for atrial fibrillation
This trial tests two different catheters that use pulsed field energy to treat atrial fibrillation (a heart rhythm problem). It aims to find which one works better for people who need blood thinners but have a high risk of bleeding.
HangzhouAges 118 years+ - NCT06802965Enrolling by invitation
Shanghai atrial fibrillation patient registry study
This study tracks people in Shanghai who have been diagnosed with atrial fibrillation (AF, a heart rhythm condition). By joining a registry, researchers can learn more about how AF is managed over time in the local population.
ShanghaiAges Any age - NCT06784466Recruiting
New ablation procedure for atrial fibrillation
This study is testing a new type of ablation procedure for atrial fibrillation (an irregular heart rhythm). It uses special energy to create scar tissue in the heart to block faulty electrical signals. If you have AF that isn’t controlled by medication, you may qualify.
Birmingham, AlabamaAges 18–80 - NCT06696170Recruiting
New catheter for atrial fibrillation using nanosecond pulses
This trial tests a new catheter that uses very short electrical pulses to treat atrial fibrillation (a type of irregular heartbeat). It may help people whose AF symptoms continue despite medication.
HasseltAges 18–75 - NCT06099106Recruiting
Testing a new device to close the left atrial appendage in AFib
This trial tests a new device called ENDOMATIC SEPIOLA that closes a small pouch in your heart (the left atrial appendage) to lower your stroke risk. It is a non-surgical option for people with atrial fibrillation who cannot take blood thinners.
TbilisiAges 18 years+ - NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06061757Recruiting
Combining 4D-ICE and TEE imaging for heart closure
This trial tests a new imaging method (4D-ICE) used alongside a standard ultrasound (TEE) during a heart procedure to close the left atrial appendage, a small pouch in the heart where clots can form in people with atrial fibrillation. The goal is to see if the new method makes the procedure safer and more precise.
Overland Park, KansasAges 18–80 - NCT06075628Recruiting
CT scan study after LAA closure procedure
This study looks at long-term outcomes after LAA closure (a procedure to reduce stroke risk) by reviewing CT scans of the device. It aims to learn if blood flow around the device affects healing and future health.
Overland Park, KansasAges 18 years+ - NCT06557616Recruiting
CoolCryo system for treating atrial fibrillation during mitral valve surgery
This trial tests a new tool called CoolCryo that freezes heart tissue to treat atrial fibrillation while you have mitral valve surgery. If you are already having this surgery and also have AF, this device could correct both problems at once.
BydgoszczAges 18 years+ - NCT06405750Recruiting
Study of the left atrial appendage during open-heart surgery
This study looks at a part of the heart called the left atrial appendage during open-heart surgery. It aims to learn more about heart rhythm problems and blood clots, which may help improve future treatments.
CopenhagenAges 18 years+ - NCT06348394Recruiting
Comparing heart imaging methods for a procedure to prevent stroke
This trial is testing two ways to guide a procedure that closes a small pouch in the heart to lower the risk of stroke in people with atrial fibrillation. The goal is to see if one method is as good or better than the other.
Plano, TexasAges 18–90 - NCT06212674RecruitingPhase 4
Stroke prevention: combined heart procedure for atrial fibrillation
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Katowice, Upper SilesiaAges 18–75 - NCT06007872Recruiting
Heart device implant using ultrasound probe inside the heart
This trial studies a procedure to implant a Watchman device using a tiny ultrasound probe placed inside the heart, avoiding a probe in the throat. It may help patients with atrial fibrillation who need to reduce stroke risk.
Cleveland, OhioAges 18 years+ - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT05565209Recruiting
Registry for closing the left atrial appendage
This study is a hospital registry that collects information from people who are having a device placed to close a part of the heart called the left atrial appendage. It helps doctors understand how this procedure works in real life, including different outcomes.
CréteilAges 18 years+ - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75 - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT04796714RecruitingPhase 4
Aspirin and clopidogrel after left heart appendix closure
This trial studies a “double anti-platelet” medicine plan (aspirin plus clopidogrel) after closing the left atrial appendage, a procedure used to reduce stroke risk in some heart rhythm conditions. It aims to find a safer, better medicine strategy for people who cannot take standard blood thinners.
PessacAges 18 years+ - NCT03243175RecruitingPhase 3
Avoiding blood thinners after brain bleeding in atrial fibrillation
This Phase 3 trial studies whether it’s safer to avoid long-term blood thinners after a spontaneous brain bleed in people with atrial fibrillation (an irregular heart rhythm). It compares different prevention strategies to lower the risk of stroke or other blood-vessel problems without causing new, serious bleeding.
LilleAges 18 years+ - NCT04240366Recruiting
Extra left atrial appendage treatment during AF ablation
This trial tests whether adding treatment to the left atrial appendage during a standard catheter ablation helps people with persistent atrial fibrillation (AF). It may improve how well AF is controlled, but you must meet specific heart rhythm and heart scan measurements to join.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT07444320Recruiting
Testing new energy pulses for atrial fibrillation treatment
This trial tests a new way to deliver energy (FARAPULSE PFA system) to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if these new waveforms can safely and effectively stop AF symptoms and improve quality of life.
SplitAges 18 years+
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Common questions
- Are there clinical trials for atrial appendage closure for atrial fibrillation?
- Yes. Clin2 currently lists 71 recruiting atrial appendage closure for atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial appendage closure for atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial appendage closure for atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.