Clinical trials
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION clinical trials
Below are recruiting atrial appendage closure for atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07301190Recruiting
Study of PFLotus for persistent atrial fibrillation
This study tests a new device called PFLotus for people with persistent atrial fibrillation (AF), a type of irregular heartbeat. The goal is to see if it can help restore a normal heart rhythm in people who haven't gotten better with medicine.
ChengduAges 18–75 - NCT06548269Recruiting
Assessing stroke recovery in patients with atrial fibrillation
This study watches how people recover from a recent stroke caused by a heart rhythm problem called atrial fibrillation (or AFib). It aims to find better ways to predict recovery and guide future care.
Jinan, ShandongAges 18 years+ - NCT06883864Recruiting
Ablation for leaky valve with constant atrial fibrillation
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Hefei, AnhuiAges 18–80 - NCT06510556Recruiting
Testing a new mapping and ablation system for AFib
This study tests a new device (FARAFLEX) that uses pulsed field energy to treat atrial fibrillation (AFib). You may qualify if you have persistent or paroxysmal AFib symptoms and have not had a prior ablation.
BrusselsAges 18 years+ - NCT04298723Recruiting
Left atrial appendage closure vs blood thinners after brain bleed
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
Mannheim, Baden-WurttembergAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT07260474Recruiting
Closing a heart pocket to prevent strokes in atrial fibrillation
This study compares two similar devices that close off a small pocket in the heart to reduce stroke risk in people with atrial fibrillation who cannot take blood thinners safely. The goal is to see which device works better and is safer.
Fuencarral-El PardoAges 18 years+ - NCT07106970Recruiting
Comparing two ablation approaches for persistent atrial fibrillation
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
BeijingAges 18–80 - NCT07620262Recruiting
Combined atrial fibrillation treatment and stroke prevention study
This study tests a new approach for people with atrial fibrillation (a type of irregular heartbeat) who are also at high risk for stroke. It combines a procedure to fix the heart's electrical signals with closing off a small pouch in the heart to reduce stroke risk, potentially avoiding long-term blood thinners.
Bay Shore, New YorkAges 18 years+ - NCT07018596Recruiting
New pulsed field ablation for paroxysmal atrial fibrillation
This trial tests a new type of heart procedure that uses gentle electrical pulses to fix abnormal signals in the upper chambers of the heart for people with a specific type of atrial fibrillation that comes and goes on its own. It may be an option if your AFib episodes stop within 7 days and medications haven't helped enough.
Prague, RoentgenovaAges 18–85 - NCT05712200RecruitingPhase 3
Abelacimab for atrial fibrillation when blood thinners aren’t suitable
This Phase 3 study tests whether abelacimab can prevent stroke and other blood-clot problems in people with atrial fibrillation (or atrial flutter) who cannot safely take usual mouth blood thinners. It also looks at safety, especially bleeding risk.
Birmingham, AlabamaAges 65 years+ - NCT05106270Recruiting
Atrial pressure changes around a heart procedure for atrial fibrillation
This trial studies how changing pressure in the heart’s upper chamber before and after a combined heart procedure affects outcomes in people with atrial fibrillation. It may help guide safer, more effective care for patients who need left atrial appendage closure (a way to reduce stroke risk).
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07287436Recruiting
Watchman device to prevent stroke in atrial fibrillation
This trial tests a device called the WATCHMAN Elite, which is placed in a small pouch of the heart to close it and reduce stroke risk, potentially allowing patients to stop blood thinners. It is for people with atrial fibrillation who cannot or prefer not to take long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07405359Recruiting
Comparing ablation methods for persistent atrial fibrillation
This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
San Francisco, CaliforniaAges 18 years+ - NCT07385417Recruiting
Early AF treatment for heart failure with preserved pumping function
This study tests using a new electrical pulse treatment for atrial fibrillation (AF) early on, in people who also have a type of heart failure where the heart pumps normally but is stiff. The goal is to see if this treatment helps manage both conditions better.
Frankfurt am MainAges 18–80 - NCT06747091Recruiting
Ablation study for people with persistent atrial fibrillation
This trial tests a catheter ablation procedure for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days but less than a year). It aims to see if the procedure is safe and effective for restoring a normal heart rhythm.
Manhasset, New YorkAges 18–80 - NCT06529978Recruiting
CoreMap heart mapping for atrial fibrillation ablation
This study tests a new mapping system that helps doctors see the electrical signals in your heart more clearly during a standard ablation for persistent atrial fibrillation. It may improve the accuracy of the treatment.
Naples, FloridaAges 18–80 - NCT06216769Recruiting
Pill-in-the-pocket blood thinners after AF ablation
This study tests a 'pill-in-the-pocket' approach for blood thinners after a catheter ablation for atrial fibrillation. Instead of taking a daily blood thinner, you may only take it when needed, which could reduce the risk of bleeding while still preventing strokes.
SeoulAges 19–89 - NCT05305612Enrolling by invitationPhase 4
Blood thinners during heart valve or left atrial appendage procedures
This study compares different ways of using blood thinners during procedures to fix a leaky mitral valve or close the left atrial appendage. The goal is to find the safest approach to prevent strokes and bleeding.
GdanskAges 18 years+ - NCT05236556Enrolling by invitation
Tracking how providers use oral blood thinners for AF
This study looks at how often and how well doctors use oral blood-thinner medicines for people with atrial fibrillation (AF) or atrial flutter (a related heart rhythm problem). It aims to see whether “provider profiling” (using clinic patterns to guide improvements) can support safer, more consistent use of these medicines.
Jacksonville, FloridaAges 18 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for atrial appendage closure for atrial fibrillation?
- Yes. Clin2 currently lists 71 recruiting atrial appendage closure for atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial appendage closure for atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial appendage closure for atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.