Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07446244Enrolling by invitation
Catheter ablation for advanced atrial fibrillation
This trial tests a special type of catheter ablation (using electric pulses called electroporation) to treat people with long-lasting atrial fibrillation and a very enlarged left atrium. It may offer a new treatment option when standard approaches are limited.
Ljubljana, OsrednjaslovenskaAges Up to 80 years - NCT07453940Enrolling by invitation
Closing off heart pouch with or without pulsed energy in atrial fibrillation
This study tests if adding a special energy treatment (pulsed field ablation) to a standard heart pouch closure is safe and works better for people with persistent atrial fibrillation who have few symptoms but a high risk of stroke.
Hangzhou, ZhejiangAges 18 years+ - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT06557876Recruiting
Pulse field ablation for atrial fibrillation mechanics
This study tests if a new type of energy called pulse field ablation (a procedure that uses short bursts of electric pulses) works as well as standard ablation for restoring normal heart rhythm in patients with episodes of irregular heartbeat. It may help your heart pump more normally.
Paris, FranceAges 18 years+ - NCT07106970Recruiting
Comparing two ablation approaches for persistent atrial fibrillation
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
BeijingAges 18–80 - NCT06516822Recruiting
Comparing two ablation methods for long-standing atrial fibrillation
This study tests whether adding extra scar lines (linear ablation) to the standard pulmonary vein isolation (CPVI) is better than CPVI alone for people with long-standing persistent AF that has lasted 1 to 3 years. The goal is to see which approach reduces AF better.
Beijing, Beijing MunicipalityAges 18–75 - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT03912324Recruiting
CT-guided heart imaging to guide treatment for atrial fibrillation
This trial studies whether using a special CT scan map of the heart muscle thickness can help doctors choose the best strategy during a cryoballoon procedure for paroxysmal atrial fibrillation. It may help improve effectiveness by tailoring treatment instead of using a standard approach.
SeoulAges 20–80 - NCT04529785Recruiting
Tested added ethanol vein treatment during repeat atrial fibrillation ablation
This trial compares two ways to help stop atrial fibrillation during a repeat procedure: standard vein isolation only versus standard isolation plus an added medicine (ethanol) into the vein of Marshall. It aims to see whether the added step improves results when atrial fibrillation returns after a previous successful treatment.
Bruges, Please SelectAges 18 years+ - NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85 - NCT05996159Recruiting
Using very high power for short duration to treat atrial fibrillation
This study tests a new way to perform a common procedure (pulmonary vein isolation) for people with paroxysmal atrial fibrillation. Instead of using the standard amount of energy for a longer time, this method uses a very high amount of energy for a very short time. This might make the procedure faster and just as safe.
SeoulAges 19 years+ - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Birmingham, AlabamaAges 18 years+ - NCT06647485Recruiting
Pulsed Field Ablation for Paroxysmal Atrial Fibrillation
This trial studies a new procedure called pulsed field ablation to treat brief episodes of atrial fibrillation (AFib). The goal is to see if it can help reset the heart's natural electrical system and reduce symptoms.
Aalst, BelgiumAges 18–70 - NCT07018596Recruiting
New pulsed field ablation for paroxysmal atrial fibrillation
This trial tests a new type of heart procedure that uses gentle electrical pulses to fix abnormal signals in the upper chambers of the heart for people with a specific type of atrial fibrillation that comes and goes on its own. It may be an option if your AFib episodes stop within 7 days and medications haven't helped enough.
Prague, RoentgenovaAges 18–85 - NCT07064616Recruiting
Pulsed field vs. cryoballoon ablation for persistent atrial fibrillation
This trial compares two techniques—pulsed field ablation and cryoballoon ablation—to treat persistent atrial fibrillation (a type of irregular heartbeat that lasts less than a year). The goal is to see which method works better and is safer for patients.
Sagamihara, KanagawaAges 18–85 - NCT07122336Recruiting
A better way to treat persistent atrial fibrillation
This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.
ShanghaiAges 18–80 - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07273994RecruitingPhase 4
Comparing two amiodarone doses after heart shock treatment for atrial fibrillation
This trial tests two different ways of taking amiodarone (a heart rhythm medicine) to keep your heart in a normal rhythm after a procedure called electrical cardioversion. It's designed for people with persistent atrial fibrillation (a fast, irregular heartbeat lasting at least 7 days).
BarcelonaAges 18 years+ - NCT07281898Recruiting
Burst stimulation for paroxysmal atrial fibrillation
This trial tests a special type of pacing called burst stimulation to see if it can help people with paroxysmal atrial fibrillation (AF) who are already scheduled for their first catheter ablation. The goal is to improve outcomes and reduce AF episodes.
Wuhan, HubeiAges 18–80 - NCT07301190Recruiting
Study of PFLotus for persistent atrial fibrillation
This study tests a new device called PFLotus for people with persistent atrial fibrillation (AF), a type of irregular heartbeat. The goal is to see if it can help restore a normal heart rhythm in people who haven't gotten better with medicine.
ChengduAges 18–75 - NCT06735534Recruiting
Repeat ablation for persistent atrial fibrillation with pulsed field
This trial tests a newer type of ablation (pulsed field ablation) for people with persistent atrial fibrillation who have already had one ablation. The goal is to see if it can fix the heart rhythm problem again.
Mobile, AlabamaAges 18 years+ - NCT07454317Recruiting
Biofeedback for managing paroxysmal atrial fibrillation
This trial tests whether biofeedback—a technique that helps you learn to control your body's stress responses—can help people with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) manage their condition better. If you have this kind of AFib and are otherwise stable, this study may be a good fit.
Liverpool, MerseysideAges 18 years+ - NCT05725187Enrolling by invitation
AI tool to predict episodes of atrial fibrillation
This study checks whether an AI prediction tool can spot people at risk for recurring episodes of atrial fibrillation (an irregular heartbeat that comes and goes). It may help doctors identify who is more likely to have paroxysmal episodes and plan care earlier.
GwangjuAges 20 years+
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Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 471 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.