Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06735001Recruiting
Finding atrial fibrillation's metabolic signature for personalized prevention
This study looks for unique metabolic patterns in people with atrial fibrillation (an irregular heartbeat). The goal is to develop personalized prevention strategies by comparing these patterns between patients and healthy volunteers.
PessacAges 18 years+ - NCT06722196RecruitingPhase 3
Amiodarone patch to prevent afib after heart surgery
This trial tests a biodegradable patch that slowly releases amiodarone directly onto the heart during surgery. It aims to prevent atrial fibrillation, a common irregular heartbeat after heart surgery.
Changchun, JinlinAges Any age - NCT06696079Recruiting
Early vs later blood thinner restart after brain bleed surgery in atrial fibrillation
This trial compares restarting a blood thinner early (within a few days) versus later (after about a week) in people who have a chronic subdural hematoma drained and also have atrial fibrillation. The goal is to find out which timing helps prevent both new bleeding and blood clots.
Oulu, North OstrobothniaAges 18 years+ - NCT06528262RecruitingPhase 4
Study of enavogliflozin to prevent atrial fibrillation return after heart ablation
This trial tests if enavogliflozin, a diabetes drug, can help prevent atrial fibrillation (an irregular heartbeat) from coming back after a catheter ablation procedure in people with heart failure. If you've recently had or are planning this procedure, this study may offer a new way to keep your heart rhythm steady.
SeoulAges 19–84 - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06500988Recruiting
Smartphone app for atrial fibrillation and weight management
This study uses a smartphone app and activity tracker to help people with atrial fibrillation (an irregular heartbeat) and a higher body weight manage their condition through tailored exercise guidance.
Baltimore, MarylandAges 18 years+ - NCT06308094Recruiting
CT scan to measure heart health before AF ablation
This trial uses a special CT scan to measure how much extra fluid is in your heart muscle. It aims to help doctors better understand and treat your atrial fibrillation before you have a procedure called ablation.
Baltimore, MarylandAges 21 years+ - NCT05991700RecruitingPhase 1/Phase 2
Grape Powder to Prevent Irregular Heartbeat After Valve Surgery
This trial tests whether a grape powder supplement (rich in plant compounds called anthocyanins) can help prevent a common heart rhythm problem (atrial fibrillation) after mitral valve repair surgery. It is for people who are scheduled for this surgery and do not have certain heart or health issues.
Ann Arbor, MichiganAges 18–79 - NCT05573633Recruiting
Smartwatch test to detect irregular heartbeats after heart surgery
This study checks whether a smartwatch can spot an irregular heartbeat called atrial fibrillation soon after on-pump heart surgery. If the smartwatch works well, it could help clinicians find the problem earlier after surgery.
AmiensAges 18 years+ - NCT05434819Recruiting
Ablation study during heart surgery for atrial fibrillation
This trial looks at whether a special heart rhythm treatment called “ablation” works well when done during certain heart operations. It may help reduce atrial fibrillation (AF) symptoms or future abnormal rhythm episodes for people who are already having surgery.
Hamilton, OntarioAges 18 years+ - NCT03611816Recruiting
Biobank study for atrial fibrillation and stroke samples
This study collects and stores medical information and biological samples from people with atrial fibrillation (or certain types of stroke). It helps researchers better understand these conditions and may support future improvements in diagnosis or treatment.
Bourg-en-BresseAges 18 years+ - NCT06874894Enrolling by invitation
Blood Thinner Safety in Asians With Atrial Fibrillation
This study is looking at how blood thinners work in Asian people with atrial fibrillation. It aims to better understand the balance between preventing strokes and the risk of bleeding.
GwangmyeongAges 1.5 years+ - NCT06054360Recruiting
Predicting irregular heartbeat after heart bypass surgery
This study uses an ultrasound test of the heart's right atrium to see if it can predict who will develop an irregular heartbeat (atrial fibrillation) after planned coronary bypass surgery. If you are scheduled for this surgery and have no history of atrial fibrillation, you may be able to join.
AmiensAges 18 years+ - NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06376916RecruitingPhase 3
Testing magnesium doses for fast heart rate in atrial fibrillation
This trial tests whether giving a higher dose of magnesium (4 grams) compared to a lower dose (2 grams) or a placebo can help control a fast heart rate during atrial fibrillation. It may help patients who are already receiving diltiazem.
Oak Lawn, IllinoisAges 18 years+ - NCT02932007RecruitingPhase 2
Chloroquine to treat ongoing atrial fibrillation symptoms
This trial tests whether chloroquine can reduce symptoms in people with persistent atrial fibrillation (AF), an irregular heartbeat that lasts longer than a week. It will also closely monitor heart rhythm and safety, since the medicine can affect the heart and other organs.
Tampa, FloridaAges 18 years+ - NCT07783984Recruiting
Comparing two procedures for persistent atrial fibrillation with enlarged left atrium
This study compares two procedures to treat persistent atrial fibrillation in people whose upper left heart chamber is enlarged: catheter ablation (a minimally invasive procedure using a tube through a vein) versus thoracoscopic ablation (a surgical approach using small chest incisions). The goal is to see which method better restores a normal heart rhythm.
Seoul, SeoulAges 19 years+ - NCT07753200RecruitingPhase 4
Comparing two blood thinners for atrial fibrillation and heart disease
This study compares two blood-thinning medicines, edoxaban and apixaban, to see which one is better at preventing strokes and bleeding in people who have both atrial fibrillation and coronary artery disease. If you're eligible, you may receive one of these standard treatments, and the trial could help find the safer option.
SeoulAges 19 years+ - NCT07641582Recruiting
Gene Testing to Predict Heart Rhythm Problems
This study uses a genetic test to identify who might develop atrial fibrillation (an irregular heartbeat) in the future. Researchers believe certain genetic patterns combined with health factors can help predict this condition early, which could lead to better prevention.
IncheonAges 20–79 - NCT07442175Recruiting
Blood pressure monitor test for atrial fibrillation detection
This trial tests a blood pressure monitor that can also detect atrial fibrillation (an irregular heartbeat). You may join if you are 22 or older, have an average-sized arm, and either have been diagnosed with AF or have never had it — as long as you don't have a pacemaker or defibrillator.
Tianjin, Tianjin MunicipalityAges 22 years+ - NCT07403760Recruiting
Ablation for atrial fibrillation in patients 80 and older
This study investigates whether a catheter ablation procedure can improve wellbeing and reduce the risk of serious events for people 80 and older with symptomatic atrial fibrillation. The goal is to see if this treatment offers better outcomes than standard care in this age group.
BeijingAges 80 years+ - NCT07275697RecruitingPhase 4
Weight loss drug and heart ablation study for AFib
This trial tests whether a weight loss medication (semaglutide) given before and after a first-time heart ablation procedure for atrial fibrillation can improve outcomes. It is for people who are overweight or obese and have certain related health conditions.
StockholmAges 18 years+ - NCT07259200Recruiting
Sleep quality after atrial fibrillation ablation
This study looks at how treating AFib with a procedure called catheter ablation might affect your sleep quality. You can join if you have AFib and are already planning to have this procedure, and you also have at least one risk factor for sleep apnea.
Grodzisk MazowieckiAges 18 years+ - NCT07227532Recruiting
Testing a new catheter for atrial fibrillation treatment
This study tests a new catheter system, called Varipulse, to see if it's safe and effective for treating atrial fibrillation (AF), a heart rhythm problem. People with short-lasting AF who haven't been helped by medication may be able to join.
Phoenix, ArizonaAges 22 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.