Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06862726Enrolling by invitationPhase 4
Comparing two blood thinners for atrial fibrillation
This study compares two commonly used blood thinners (apixaban and rivaroxaban) to see which works better for people with non-valvular atrial fibrillation, a type of irregular heartbeat. The goal is to find the safest and most effective option for preventing strokes.
TunisAges 18–80 - NCT06716021RecruitingPhase 3
Etripamil for rapid heart rate in atrial fibrillation
This trial tests a medication called etripamil to see if it can quickly slow down a rapid heart rate during episodes of atrial fibrillation. It may help people who have frequent, long-lasting episodes with a fast heartbeat.
West Hills, CaliforniaAges 18 years+ - NCT05557526Recruiting
Improving quality of life after atrial fibrillation ablation
This study aims to improve how patients feel in daily life after a procedure to treat atrial fibrillation (an irregular heartbeat). It focuses on whether better patient expectations and support can lead to a better quality of life after the procedure.
Düsseldorf, North Rhine-WestfaliaAges 18 years+ - NCT04685317Recruiting
Sentinel brain-protection device during atrial fibrillation ablation
This trial tests whether a specialized “brain protection” device can improve safety during atrial fibrillation (AF) catheter ablation. It may help reduce the risk of stroke or related complications while treating AF.
Rochester, MinnesotaAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT06207383Recruiting
Comparing heart treatments for atrial fibrillation and heart failure
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
GrazAges 60 years+ - NCT06401616RecruitingPhase 4
Stopping blood thinners after heart surgery for atrial fibrillation
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
Copenhagen, Capital RegionAges 18 years+ - NCT06823778Recruiting
Preventing irregular heartbeat after heart surgery with radiofrequency
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
Moscow, MoscowAges 18 years+ - NCT07220525Recruiting
Sleep and heart rhythm study for people with sleep apnea device
This study looks at how turning off your sleep apnea device for short periods affects your heart rhythm, especially if you have a condition like atrial fibrillation. It may help understand the link between sleep and heart health.
San Francisco, CaliforniaAges 21 years+ - NCT07272902Recruiting
Atrial fibrillation treatment: Ablation vs. medication
This trial compares two ways to treat atrial fibrillation in people with heart failure where the heart's pumping strength is still normal. You'll either get a procedure called ablation to restore normal rhythm or medication to control your heart rate. The goal is to see which approach works better for people like you.
Halifax, Nova ScotiaAges 18 years+ - NCT05080712Recruiting
Tracking how atrial fibrillation changes over time in young people
This study focuses on people who have atrial fibrillation (an irregular heartbeat) and whose diagnosis was made within the last year. It aims to understand how atrial fibrillation progresses, which could help guide better monitoring and future care.
StockholmAges 18–50 - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05610215Recruiting
Hybrid or catheter ablation for atrial fibrillation in hypertrophic heart
This trial compares two procedures to treat atrial fibrillation (an irregular heartbeat) in people who also have hypertrophic cardiomyopathy (thickened heart muscle). It looks at whether the hybrid approach or a catheter-based approach works better for controlling symptoms and heart rhythm.
BeijingAges 18 years+ - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT07726901Recruiting
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two techniques for treating persistent atrial fibrillation: one uses standard anatomy-based ablation, and the other uses a special mapping system to guide the procedure. It aims to find which method works better for people who have not had prior ablation.
Seoul, SeoulAges 19 years+ - NCT07611084Recruiting
Atrial Fibrillation Study in Older Adults in Rural China
This study follows older adults in rural China who have atrial fibrillation (an irregular heart rhythm) to better understand the condition and screen for heart failure. Researchers want to learn more about how these conditions affect people in rural communities.
Taizhou, JiangsuAges 65–80 - NCT07551947Enrolling by invitation
Insulin Resistance and Heart Rhythm Ablation Success
This study examines whether how your body handles insulin (a hormone that controls blood sugar) affects the success of a new ablation procedure called pulsed field ablation, which treats irregular heart rhythms. Researchers want to understand which patients benefit most from this treatment.
TřinecAges 18 years+ - NCT07436299Recruiting
New ultrasound method for heart pressure in atrial fibrillation
This study tests a new way to use ultrasound (echocardiogram) to measure heart pressure in people who have both heart failure and atrial fibrillation (irregular heartbeat). Participants will have an ultrasound and a heart catheterization to see if the new ultrasound method can accurately detect elevated pressures.
Cleveland, OhioAges 18 years+ - NCT07434674Recruiting
Long-Term Atrial Fibrillation After Acute Illness Study
This study is for people who recently had atrial fibrillation (an irregular heartbeat) for the first time while in the hospital or sick. It uses a small implantable heart monitor to see if the irregular heartbeat comes back over the next few years.
La Jolla, CaliforniaAges 18 years+ - NCT07380620Enrolling by invitation
Step-by-step treatment for persistent atrial fibrillation
This trial tests a step-by-step treatment plan for people with persistent atrial fibrillation (a type of irregular heartbeat) who live in Southwest China. The goal is to find a better way to manage and possibly fix this heart condition.
ChongqingAges 18 years+ - NCT07139314Recruiting
Timing of blood thinners after stroke clot removal
This trial is testing the best time to start blood thinners (anticoagulation) after emergency stroke treatment in people who have atrial fibrillation. It is for patients who had a certain type of bleeding in the brain after the procedure.
Ma’anshan, AnhuiAges 18 years+ - NCT07063381Enrolling by invitation
Low-frequency stimulation for cognition in atrial fibrillation
This study tests whether low-frequency electrical stimulation can help improve thinking and memory in people with permanent atrial fibrillation and cognitive impairment. Participants will receive the stimulation and have their cognitive function checked over six months.
MoscowAges 60–90
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.