Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07438054Enrolling by invitation
Yearly heart-rhythm screening for adults 65 and older
This study tests whether monthly heart checks using a simple ECG (a quick test of your heart's electrical activity) can find a common heart-rhythm problem called atrial fibrillation earlier. You would visit your family health center once a month for 12 months to get the ECG done, no extra procedures or treatments are involved.
Ordu, OrduAges 65 years+ - NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Dothan, AlabamaAges 18 years+ - NCT06396299Recruiting
Atrial fibrillation blood thinner outcomes study
This study follows people with atrial fibrillation to see how well blood-thinning medications work and what outcomes they experience over time. It aims to improve treatment guidance for patients with this common heart rhythm condition.
Bangkok, BangkokAges 18–100 - NCT07085650Recruiting
Atrial Fibrillation Ablation Study
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
Shenyang, LiaoningAges 18 years+ - NCT06728826Recruiting
Preventing atrial fibrillation after heart surgery with pericardiotomy
This study tests if opening the sac around the heart (pericardiotomy) can lower the chance of developing an irregular heartbeat called atrial fibrillation after heart surgery. It is for people having surgery on the heart's valves, major blood vessels, or arteries.
ShanghaiAges 18 years+ - NCT06719921Enrolling by invitation
Catheter ablation for atrial fibrillation without x-ray
This study tests a way to perform catheter ablation for atrial fibrillation using a non-fluoroscopic lab, meaning no x-ray is needed during the procedure. It may help patients avoid radiation exposure.
Hangzhou, ZhejiangAges 18 years+ - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT05029570Recruiting
Heart rate control for permanent atrial fibrillation and heart failure
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
Madrid, MadridAges 18 years+ - NCT06486792RecruitingPhase 4
Stroke prevention in patients with hidden atrial fibrillation
This trial tests if starting blood thinners can prevent another stroke in people who had a stroke but were found to have a hidden heart rhythm problem called atrial fibrillation. It is for older adults who have had a recent stroke without a known cause.
Paris, ParisAges 65 years+ - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Rockford, IllinoisAges 18 years+ - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT04880265Recruiting
Study heart rhythm changes after open-heart surgery
This study looks at how often and how long an irregular heartbeat (atrial fibrillation) happens after planned open-heart surgery. It aims to better understand the “burden” of this rhythm problem, which could help improve care for future patients.
Boston, MassachusettsAges 20–90 - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT04529785Recruiting
Tested added ethanol vein treatment during repeat atrial fibrillation ablation
This trial compares two ways to help stop atrial fibrillation during a repeat procedure: standard vein isolation only versus standard isolation plus an added medicine (ethanol) into the vein of Marshall. It aims to see whether the added step improves results when atrial fibrillation returns after a previous successful treatment.
Bruges, Please SelectAges 18 years+ - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06212791Recruiting
Exercise MRI Study of Heart Function After Ablation
This study uses an exercise MRI to look at how the upper chambers of the heart (left atrium) work after ablation for atrial fibrillation. It may help doctors understand if the procedure improves heart function during exercise.
Richmond, VirginiaAges 18 years+ - NCT04240366Recruiting
Extra left atrial appendage treatment during AF ablation
This trial tests whether adding treatment to the left atrial appendage during a standard catheter ablation helps people with persistent atrial fibrillation (AF). It may improve how well AF is controlled, but you must meet specific heart rhythm and heart scan measurements to join.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT05378308Recruiting
Tracking blood thinner use in people with AF or blood clots
This registry study looks at how people with atrial fibrillation (AF) or blood clots (VTE) use blood thinners, especially NOACs, over time. It may help doctors better understand real-world patterns of treatment and outcomes.
Zhengzhou, HenanAges Any age - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT07430007Recruiting
Exercise and diet to reduce AFib burden
This study tests whether a program of exercise and healthy eating changes can reduce how often atrial fibrillation (AFib) happens and help you lose weight. It may be a good fit if you are overweight, have AFib, and are ready to make lifestyle changes.
Jyväskylä, Central FinlandAges 18–75
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.