Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 547 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06078735Recruiting
Device vs manual pressure for closing blood vessels after AFib procedure
This study compares two ways to close the vein entry after heart ablation for AFib: the LockeT device versus manual compression. It helps find which method works better.
Overland Park, KansasAges 18 years+ - NCT06174506Recruiting
Predicting atrial fibrillation in pacemaker patients
This study is looking at whether two blood tests (hs Troponin I and NT-proBNP) can help predict if people with a permanent pacemaker will develop atrial fibrillation, a common heart rhythm problem. If you need a pacemaker, you may be able to join and help researchers learn more.
Ho Chi Minh City, None SelectedAges 18 years+ - NCT06333327Recruiting
Atrial fibrillation ablation with a balloon catheter registry
This study is collecting data on people having a procedure called catheter ablation for atrial fibrillation using a special radiofrequency balloon. The goal is to see how well it works and to help improve future treatments.
BrusselsAges 18–85 - NCT06396299Recruiting
Atrial fibrillation blood thinner outcomes study
This study follows people with atrial fibrillation to see how well blood-thinning medications work and what outcomes they experience over time. It aims to improve treatment guidance for patients with this common heart rhythm condition.
Bangkok, BangkokAges 18–100 - NCT06486792RecruitingPhase 4
Stroke prevention in patients with hidden atrial fibrillation
This trial tests if starting blood thinners can prevent another stroke in people who had a stroke but were found to have a hidden heart rhythm problem called atrial fibrillation. It is for older adults who have had a recent stroke without a known cause.
Paris, ParisAges 65 years+ - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT06560047Recruiting
Early catheter ablation for atrial fibrillation with heart failure
This trial tests whether early catheter ablation (a procedure to fix irregular heartbeats) helps people who have both heart failure and atrial fibrillation. It looks at how this treatment affects your heart function and quality of life.
AalborgAges 18–80 - NCT07085650Recruiting
Atrial Fibrillation Ablation Study
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
Shenyang, LiaoningAges 18 years+ - NCT03357926Recruiting
Building predictions for atrial fibrillation in pacemaker patients
This study creates a database to better predict who with a pacemaker or ICD will develop atrial fibrillation (an irregular heart rhythm). It may help your care team spot risk earlier and tailor monitoring sooner.
GrazAges 18 years+ - NCT04880265Recruiting
Study heart rhythm changes after open-heart surgery
This study looks at how often and how long an irregular heartbeat (atrial fibrillation) happens after planned open-heart surgery. It aims to better understand the “burden” of this rhythm problem, which could help improve care for future patients.
Boston, MassachusettsAges 20–90 - NCT07438054Enrolling by invitation
Yearly heart-rhythm screening for adults 65 and older
This study tests whether monthly heart checks using a simple ECG (a quick test of your heart's electrical activity) can find a common heart-rhythm problem called atrial fibrillation earlier. You would visit your family health center once a month for 12 months to get the ECG done, no extra procedures or treatments are involved.
Ordu, OrduAges 65 years+ - NCT06719921Enrolling by invitation
Catheter ablation for atrial fibrillation without x-ray
This study tests a way to perform catheter ablation for atrial fibrillation using a non-fluoroscopic lab, meaning no x-ray is needed during the procedure. It may help patients avoid radiation exposure.
Hangzhou, ZhejiangAges 18 years+ - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06212791Recruiting
Exercise MRI Study of Heart Function After Ablation
This study uses an exercise MRI to look at how the upper chambers of the heart (left atrium) work after ablation for atrial fibrillation. It may help doctors understand if the procedure improves heart function during exercise.
Richmond, VirginiaAges 18 years+ - NCT04240366Recruiting
Extra left atrial appendage treatment during AF ablation
This trial tests whether adding treatment to the left atrial appendage during a standard catheter ablation helps people with persistent atrial fibrillation (AF). It may improve how well AF is controlled, but you must meet specific heart rhythm and heart scan measurements to join.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT04528511Recruiting
Studying new atrial fibrillation after heart attack
This study looks at how often atrial fibrillation happens soon after an acute heart attack, and who is most at risk. It may help doctors identify patients who need closer heart-rhythm monitoring after a hospital heart attack.
Kaifeng, HenanAges 18 years+ - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT05378308Recruiting
Tracking blood thinner use in people with AF or blood clots
This registry study looks at how people with atrial fibrillation (AF) or blood clots (VTE) use blood thinners, especially NOACs, over time. It may help doctors better understand real-world patterns of treatment and outcomes.
Zhengzhou, HenanAges Any age - NCT05565781Recruiting
Watch for hidden atrial fibrillation after unexplained stroke
This study uses a smartwatch and a longer heart-monitoring test (a Holter) to find an irregular heart rhythm called atrial fibrillation after a stroke whose cause is unclear. If they detect it, it may help guide better prevention and treatment to reduce future stroke risk.
Barcelona, CataloniaAges 55 years+ - NCT06063538RecruitingEarly Phase 1
Preventing irregular heartbeat after heart surgery with amiodarone
This trial tests if placing a small amount of amiodarone medicine near the heart during open-chest surgery can help prevent a common irregular heartbeat (atrial fibrillation) that often happens after heart surgery.
Chicago, IllinoisAges 20–85 - NCT06556732RecruitingPhase 1
Eplerenone for preventing atrial fibrillation return
This trial is testing whether a medication called eplerenone can help prevent atrial fibrillation (AF) from coming back in people who have structural heart disease and have already had their heart rhythm restored to normal. It may be a good option if you are looking for a way to keep your heart in a normal rhythm.
AsyutAges 20–70 - NCT06798714RecruitingPhase 4
Colchicine to prevent irregular heartbeat after heart surgery
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
TomskAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 547 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.