Clinical trials
Back Pain Lower Back Chronic clinical trials
Below are recruiting back pain lower back chronic clinical trials, each written for real people, not researchers. We’re tracking 108 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT06741579RecruitingPhase 3
Pain relief study for nerve injury pain
This trial tests how well two types of peripheral nerve stimulation (PNS) devices relieve chronic pain caused by a single nerve injury. It looks for people who already have a referral for PNS therapy as part of their usual care and who have gotten at least 50% relief from a diagnostic nerve block.
Palo Alto, CaliforniaAges 18 years+ - NCT06706479Enrolling by invitation
Brain stimulation for balance in older adults with back pain
This study tests whether a gentle, non-invasive electrical brain stimulation technique (called high-definition tDCS) can improve balance in older adults with chronic low back pain. Participants receive either real or sham stimulation during balance training sessions.
Hong Kong, Hong KongAges 60–85 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06696300Recruiting
Breathing muscle training for chronic low back pain
This study tests whether training the muscles you use to breathe can help reduce chronic low back pain. You will practice specific breathing exercises and see if they improve your pain and function.
Kırşehir, CenterAges 18–65 - NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT06419439RecruitingPhase 2
Ketamine for Veterans with Chronic Back Pain and Depression
This study tests whether ketamine, combined with talk therapy, can help veterans with both chronic low back pain and depression. The goal is to reduce pain and improve mood.
Ann Arbor, MichiganAges 18 years+ - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75 - NCT05345015Recruiting
Radio waves for muscle or low back pain and function
This trial tests whether a high-frequency radio-wave treatment can reduce pain and improve movement in adults with a muscle strain (hamstring) or acute or chronic low back pain. It may help you feel less pain and function better, depending on your specific injury and medical details.
KavalaAges 18–65 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT05991440Recruiting
Race and income differences in chronic low back pain study
This study looks at how race and income affect chronic low back pain. Researchers want to understand differences in pain and daily function between Black and White adults with long-lasting back pain.
St Louis, MissouriAges 18–85 - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT05843890Recruiting
Personalized pain guide for chronic low back pain
This study tests a tailored (personalized) pain guide to help people with long-lasting lower back pain. It may help by teaching strategies to reduce how pain interferes with daily life.
Ann Arbor, MichiganAges 18 years+ - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT05669027Recruiting
Mobile brain training to help low back pain
This study tests whether mobile “neurofeedback” training can reduce low back pain and improve how much it affects your daily life. You would likely use sensors that measure brain and body signals to guide the training.
Durham, North CarolinaAges 18–90 - NCT05657964Recruiting
Study of a back pain exercise program for chronic low back pain
This trial tests whether a structured exercise/education program can help people with chronic lower back pain. You may qualify if your pain and disability scores are high enough and you can complete study activities in English.
Redwood City, CaliforniaAges 18–65 - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45
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Common questions
- Are there clinical trials for back pain lower back chronic?
- Yes. Clin2 currently lists 108 recruiting back pain lower back chronic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a back pain lower back chronic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a back pain lower back chronic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.