Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07013344Recruiting
Link between NT-proBNP and heart artery disease
This study looks at a blood test called NT-proBNP to see if it can help predict how much blockage is in the heart's arteries. It may help doctors better understand heart disease risk.
Milan, ItalyAges 18 years+ - NCT02714387Recruiting
Study of serious complications from non-traumatic blood vessel brain problems
This study follows people who have non-injury (non-traumatic) blood-vessel-related problems in the brain to understand serious complications. It may help researchers identify risks and improve care over time.
AngersAges 15 years+ - NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT07067229Recruiting
Brain stimulation and exercise for motor neuron disease
This study tests whether combining non-invasive brain stimulation (a gentle, non-surgical treatment) with exercise can help people with motor neuron disease (MND). It may improve movement and quality of life for those with mild to moderate symptoms.
Bangkok, PathumwanAges 18–80 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Tucson, ArizonaAges Any age - NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT07279740RecruitingPhase 2
Brain stimulation plus medication for apathy in dementia
This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.
Toronto, OntarioAges Any age - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT07871487Recruiting
Brain protein changes after hip or knee replacement surgery
This study looks at whether having hip or knee replacement surgery with spinal anesthesia affects certain proteins in the brain that are linked to memory and thinking. It compares people having surgery with people who have arthritis but are not having surgery, to help understand if the surgery causes any short-term brain changes.
UppsalaAges 55–75 - NCT07745712Recruiting
Testing a robotic exoskeleton for children with walking difficulties
This trial tests a robotic exoskeleton called ABLE Kids to help children with walking difficulties due to neurological or muscle conditions. It checks if the device is safe and works well. Children who meet certain size and health requirements may be eligible to participate.
Girona, GironaAges Up to 17 years - NCT07571486RecruitingPhase 1/Phase 2
Opening the blood-brain barrier for ALS treatment
This trial tests a device that temporarily opens the barrier between the blood and brain to see if it can help slow down ALS. It may allow treatments to reach the brain more effectively.
ParisAges 18–80 - NCT07402928Recruiting
Dopamine signals in health and Parkinson's
This study uses MRI scans to look at dopamine signals in the brain. The goal is to understand how Parkinson's affects these signals.
HvidovreAges 35 years+ - NCT07285642Recruiting
Oxygen levels in muscles and brain in COPD patients
This study measures oxygen levels in your brain and leg muscles during exercise to understand how COPD affects them.
IstanbulAges 40–70 - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT07863011Recruiting
Low-dose brain radiation for mild Alzheimer's disease
This study tests a low dose of radiation to the whole brain combined with an experimental drug to see if it can slow down the effects of mild Alzheimer's disease. It aims to help people with mild dementia think more clearly and keep their daily abilities for as long as possible.
Cheonan, Chungcheongnam-doAges 60–85 - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT07624630Recruiting
Brain Activity and Walking After Stroke
This study examines how your brain works when you walk and think at the same time after stroke. Researchers will use brain imaging to understand this process, which could help develop better rehabilitation strategies.
Solna, Stockholm CountyAges 18 years+
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 328 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.