Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT05085704Recruiting
Brain scans to study metabolism in healthy and diabetic people
This study uses MRI brain scans at different strengths to measure how the brain uses energy (metabolism) in health and in people with genetically confirmed G1D. It may help researchers understand brain energy changes related to metabolic disease and diabetes.
New York, New YorkAges 16–80 - NCT05082961Recruiting
Blood immune markers and brain radiation after head/neck surgery
This study looks at immune system signals in your blood during and after postoperative radiation therapy for certain head and neck cancers involving the brain or skull base. Researchers want to see whether these “immune markers” relate to treatment response or side effects.
CaenAges 18 years+ - NCT05085210Recruiting
Brain stimulation to improve parts of lost vision
This study tests whether a noninvasive brain stimulation treatment (tRNS) plus visual training can improve visual field problems after a stroke. It may help some people regain better visual perception in the area they lost.
Boston, MassachusettsAges 18–80 - NCT05097001Recruiting
Personalized brain-stimulation program for dystonia using imaging
This study tests whether using brain imaging to guide stimulation settings can improve symptoms in people with long-term deep brain stimulation for dystonia. It will compare different stimulation approaches in a blinded, step-by-step crossover design to see which one helps more.
Würzburg, BavariaAges 18 years+ - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05106725Recruiting
Wearable health tracking study for cancer and brain conditions
This study tests wearable devices and related health measurements (“biomarkers”) in people who have cancer-related nerve problems, a brain/neurological condition, or who are healthy for comparison. It may help researchers better understand health signals over time in these groups.
San Diego, CaliforniaAges 18 years+ - NCT05111977Recruiting
Study of gut-body signals in anorexia nervosa
This trial studies how your gut and brain communicate in people with anorexia nervosa. It may help researchers understand symptoms and find better ways to measure or treat the condition.
Tulsa, OklahomaAges 15–40 - NCT05115474RecruitingPhase 2
Screening brain MRI study for stage IV breast cancer
This trial checks whether taking screening brain MRI scans in people with stage IV breast cancer helps find brain involvement earlier. It may help guide treatment decisions for those who would otherwise only get brain imaging after symptoms start.
Clearwater, FloridaAges 18 years+ - NCT05115929Recruiting
Surgery for dangerously high pressure after head injury
This trial compares two emergency surgery approaches for people with traumatic brain injury who have dangerously high pressure inside the skull that does not improve with standard treatments. The goal is to see which approach leads to better long-term outcomes.
ClamartAges 18–65 - NCT05120635Recruiting
Study brain signals tied to fear and anxiety in RNS patients
This study records electrical brain activity to understand how fear and anxiety work in people who already have an RNS (responsive neurostimulation) device placed. It may help researchers develop better ways to monitor and treat anxiety-related symptoms in the future.
Los Angeles, CaliforniaAges 18–70 - NCT05129150Recruiting
Assessing brain function with an ultrasound in a day hospital
This trial studies brain function in people who are already going to a day hospital for memory and thinking assessments. It may help researchers better understand cognitive problems and improve how they are evaluated. You would likely be asked to complete an ultrasound exam of the brain and allow your information to be used for the study.
ToursAges Any age - NCT05139277Recruiting
Using a imaging system during brain tumor surgery
This study tests the CONVIVO system to help surgeons see certain brain tumors during surgery. It may help make operations safer and more effective by improving how tumors are identified.
Lebanon, New HampshireAges 18 years+ - NCT05160129Recruiting
Deep brain stimulation for severe OCD using targeted electrodes
This study tests a deep brain stimulation (DBS) treatment device for adults with severe, long-lasting obsessive-compulsive disorder (OCD) that has not improved with standard treatments. It may help reduce OCD symptoms and improve daily functioning when medications and therapy have not worked.
New York, New YorkAges 18 years+ - NCT05176392Recruiting
Stimulation treatment plus therapy for post-injury headaches
This study tests whether a noninvasive brain stimulation treatment combined with therapy can reduce long-lasting headaches after a mild brain injury. You might be a good candidate if your headaches started after the injury and have continued for months.
San Diego, CaliforniaAges 18–65 - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT05183152Recruiting
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT05194098Recruiting
EEG and brain stimulation study for depression reward symptoms
This study uses non-invasive brain stimulation (like TMS) and EEG brain recordings to measure how the brain’s “reward” system works in people with major depression. It may help researchers understand which stimulation approaches best affect depression-related reward processing.
San Francisco, CaliforniaAges 18–65 - NCT05197764Recruiting
Track muscle growth in young children with spastic cerebral palsy
This study looks at how the muscles in the body grow in infants and young children with spastic cerebral palsy (a type of movement difference). It may help doctors better understand normal growth patterns and how care choices affect muscle development.
Leuven, Vlaams-BrabantAges 6 months–9 years - NCT05212272Recruiting
MRI plus cognitive testing during glioma chemoradiation
This study uses MRI scans and related brain/cognitive testing while you receive standard chemotherapy and radiation for a high-grade brain tumor. It aims to see how MRI measures and brain testing may relate to your treatment response or brain function.
Winston-Salem, North CarolinaAges 18 years+ - NCT05213169RecruitingPhase 2/Phase 3
Apomorphine for severe unresponsive brain injuries
This trial tests whether apomorphine can improve care or outcomes for people in an unresponsive wakefulness or minimally conscious state after a brain injury. It is designed for patients who are medically stable and not currently on certain brain- or heart- affecting medicines.
Liège, LiegeAges 18–80
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.