Clinical trials
Breast Cancer Screening and Diagnosis clinical trials
Below are recruiting breast cancer screening and diagnosis clinical trials, each written for real people, not researchers. We’re tracking 256 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06508216RecruitingPhase 1/Phase 2
New drug combo for early relapsed triple-negative breast cancer
This trial tests experimental drugs for people with triple-negative breast cancer that came back within 12 months of finishing initial treatment. The goal is to see if these drugs are safe and can shrink or slow the cancer.
VillejuifAges 18 years+ - NCT06545682RecruitingPhase 1
Study of alpelisib and pembrolizumab for advanced breast cancer or melanoma
This trial tests a combination of two drugs, alpelisib and pembrolizumab, for people with advanced triple-negative breast cancer or melanoma that has spread. The goal is to see if the combination can help shrink tumors, including those that have spread to the brain.
Houston, TexasAges 18 years+ - NCT06568692RecruitingPhase 2
Study of PCS6422 with capecitabine for advanced breast cancer
This trial tests a new drug combination (PCS6422 plus capecitabine) for people with advanced or metastatic breast cancer that has not responded to other treatments. The goal is to see if adding PCS6422 can make the chemotherapy work better.
Tucson, ArizonaAges 18 years+ - NCT06611813RecruitingPhase 2
Chemo plus immunotherapy for HR+/HER2- breast cancer
This trial tests whether adding an immunotherapy drug (toripalimab) to standard chemotherapy before surgery can help treat HR+/HER2- breast cancer. It is for women with early-stage breast cancer that has not spread to other parts of the body.
HangzhouAges 18–75 - NCT06629896Recruiting
Comparing contrast mammogram vs MRI for high-risk breast cancer surveillance
This trial compares two advanced imaging methods—contrast-enhanced mammography and MRI—to see which is better for detecting breast cancer early in women at high risk. If you are at high risk and have not had breast cancer before, this study could help guide your future screening.
Reggio Emilia, Italy/Reggio EmiliaAges 35–60 - NCT06746688RecruitingPhase 1
Safety study of ES2B-C001 for HER2-positive metastatic breast cancer
This trial tests a new drug called ES2B-C001, with or without an adjuvant, to see if it is safe for people with HER2-positive breast cancer that has spread and has not responded to previous treatments.
GrazAges 18 years+ - NCT06822582Recruiting
Pelvic health rehab after breast or gynecologic cancer
This trial tests a pelvic health rehabilitation program for people who have had breast or gynecologic cancer. It aims to help with pelvic floor problems like bladder or bowel issues that can start during or after treatment.
Edmonton, AlbertaAges 18 years+ - NCT06833502RecruitingPhase 2
Screening for breast cancer spread after chemo and surgery
This trial aims to find out if doing special scans to check for breast cancer spread to organs (not just lymph nodes) is helpful in certain patients. The study looks at people with breast cancer that had already spread to lymph nodes and did not completely go away with chemotherapy and surgery.
Tampa, FloridaAges 18 years+ - NCT06943521RecruitingPhase 1/Phase 2
Study of MT-4561 for advanced solid tumors
This trial tests a new drug called MT-4561 in people with advanced solid tumors that have not responded to prior treatments. It aims to see if the drug can help shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT07075679Recruiting
AI vs double reading for breast cancer screening
This study compares a single radiologist reading your mammogram with help from artificial intelligence (AI) to the standard method of two radiologists reading it. The goal is to see if AI-assisted reading is just as good at finding cancer while saving time and resources.
OlomoucAges 45–69 - NCT07076147Recruiting
Breast cancer screening follow-up for moderate-risk women
This study looks at how well women with a moderate risk of breast cancer follow their screening recommendations (like yearly MRI or mammogram). It may help women who have certain genetic variants or a higher calculated risk stay on top of their breast health.
Los Angeles, CaliforniaAges 30–75 - NCT07117864Recruiting
T-DXd with brain radiation for HER2+ breast cancer
This trial tests a new combination of a targeted drug (T-DXd) with brain radiation for women with breast cancer that has spread to the brain and is HER2-positive or HER2-low. The goal is to see if this approach is safe and works better than radiation alone.
Beijing, Beijing MunicipalityAges 18–75 - NCT07198724RecruitingPhase 1/Phase 2
A study of elacestrant plus Enhertu for advanced breast cancer
This trial tests a new combination of two targeted drugs (elacestrant and Enhertu) for people with a specific type of advanced breast cancer (HR-positive, HER2-low or ultra-low) that did not respond to standard treatments like CDK4/6 inhibitors. The goal is to see if this combination works better than current options.
Boston, MassachusettsAges 18 years+ - NCT07214883Recruiting
Breast imaging study for adults
This study collects breast cancer imaging tests to build a teaching library. You can join if you are 18 or older and have had a breast imaging test in the US.
Orlando, FloridaAges 18 years+ - NCT07219277Recruiting
Blood test to detect breast cancer early in women
This study tests a new blood test that aims to find breast cancer early in women who are at higher risk or are going for routine screening. If you are a woman aged 30–75 and are scheduled for a mammogram, MRI, or breast ultrasound, you may be able to help validate this test.
Phoenix, ArizonaAges 30–75 - NCT07231159Recruiting
Cancer screening help at community spots
This trial tests a program to help people get screened for lung, breast, or prostate cancer at community resource spots. If you are at risk and screen positive, you may be able to join.
Orlando, FloridaAges 18 years+ - NCT07273812Recruiting
AI phone app to help with chemotherapy side effects in breast cancer
This trial tests a mobile app that uses artificial intelligence to help women with early-stage breast cancer manage symptoms during their first chemotherapy. The app is in Arabic and is designed to make it easier to report how you're feeling and get support.
BaghdadAges 18 years+ - NCT07383506RecruitingPhase 1
Study of a targeted pill for PIK3CA-mutated advanced cancers
This trial tests a new pill (CGT6297) that targets cancer cells with a specific PIK3CA gene change. It may be an option for people with certain advanced solid tumors, including endometrial or breast cancer, after standard treatments have stopped working.
Scottsdale, ArizonaAges 18 years+ - NCT07357298RecruitingPhase 3
Brain MRI surveillance for stage IV breast cancer
This trial tests whether regular brain MRI scans can help detect brain metastases early in patients with stage IV breast cancer who do not yet have any known brain metastases. The goal is to see if early detection improves outcomes.
Miami, FloridaAges 18 years+ - NCT07371208RecruitingPhase 2
Sac-TMT plus immunotherapy before surgery for triple-negative breast cancer
This study tests a combination of two drugs—Sacituzumab Tirumotecan (Sac-TMT) and an immunotherapy called KL-A167—given before surgery to shrink triple-negative breast tumors. It aims to improve outcomes for people with early-stage, high-risk breast cancer who have not yet had any treatment.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT01521741Recruiting
Breast cancer lymphedema screening to detect early swelling
This trial looks at whether scheduled measurements can spot early swelling (lymphedema) in people with breast cancer. It may help find problems sooner so treatment or prevention steps can start earlier.
Boston, MassachusettsAges 18 years+ - NCT01785420RecruitingPhase 3
Trastuzumab before breast surgery for HER2-positive cancer
This trial tests whether giving trastuzumab before surgery can improve outcomes for people with HER2-positive early breast cancer. Trastuzumab is a targeted medicine that helps treat HER2-driven cancer before the tumor is removed.
MumbaiAges 18–80 - NCT02732171Recruiting
Blood and bone marrow tests to track breast cancer return
This trial checks whether specific “surveillance” markers (measured from blood and bone marrow) can help predict if breast cancer comes back after standard treatments. It may help doctors monitor you more accurately and earlier if recurrence risk is high.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02620852Recruiting
Wisdom Study: Women’s breast cancer screening decisions
This study looks at how to decide the best breast cancer screening (like mammograms) based on your personal risk. It may help by testing a smarter way to match screening to your risk level.
Birmingham, AlabamaAges 30–74
Hear when a new Breast Cancer Screening and Diagnosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for breast cancer screening and diagnosis?
- Yes. Clin2 currently lists 256 recruiting breast cancer screening and diagnosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer screening and diagnosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer screening and diagnosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.