Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 389 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07442448Enrolling by invitationPhase 4
Study of Finerenone for heart and kidney health in diabetes
This trial tests a medication called Finerenone to see if it can improve heart structure and function in people with both diabetic kidney disease and heart failure. If you have type 2 diabetes, kidney problems, and heart failure with preserved pumping function, this study may explore a new treatment option for you.
TaipeiAges 18 years+ - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07419360Recruiting
Draining fluid from lungs in heart failure
This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.
Albany, New YorkAges 18 years+ - NCT07405944RecruitingPhase 4
Vericiguat for improving heart function in heart failure
This study tests a medicine called vericiguat (a pill) to see if it can improve the heart's shape and function in people with heart failure and a weakened pump. You would keep taking your usual heart medications plus the study drug.
IzolaAges 18 years+ - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07379840Recruiting
Finerenone for chronic heart failure in South Korea
This trial tests how safe and effective finerenone is for adults with chronic heart failure. It includes people whose heart pumps blood with at least 40% efficiency.
Multiple LocationsAges 19 years+ - NCT07369856Recruiting
Using urine sodium to guide diuretic dosing in heart failure
This trial uses a simple urine test to see if your current water pill dose is right for you. The goal is to find the best dose to reduce symptoms and avoid hospital visits.
Vancouver, British ColumbiaAges 18 years+ - NCT07356843Recruiting
Palliative Care for Heart Failure Patients
This study looks at how to improve palliative care for people with heart failure. It involves healthcare workers who care for heart failure patients and will help find better ways to support them.
Indianapolis, IndianaAges 18 years+ - NCT06851949RecruitingPhase 2
Vsling device for ventricular repair in heart failure
This trial tests a new device called Vsling, which is placed inside the heart to help reshape the main pumping chamber (left ventricle) in people with heart failure. It may improve your heart's strength and reduce symptoms like shortness of breath.
Be’er Ya‘aqovAges 18 years+ - NCT06381427Recruiting
Improving care for older heart patients before surgery
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
GiessenAges 65 years+ - NCT07350759Recruiting
Using a wearable to detect heart failure worsening
This study tests if a wearable device can spot early signs of heart failure getting worse. If you already use a heart monitor and have stable readings, you may help show how a non-invasive wearable could alert you sooner.
Tampa, FloridaAges 18 years+ - NCT07325942Recruiting
Low vs high volume high-intensity interval training for heart failure
This study compares two different types of high-intensity interval exercise programs (one shorter, one longer) in people with chronic heart failure. It aims to see which program improves heart health and daily function more.
Cairo, Giza GovernorateAges 18 years+ - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT07319039Recruiting
Brain scan study of breathlessness in cancer, COPD, and heart failure
This study uses a brain scan (fMRI) to learn how the brain processes shortness of breath in people with advanced heart failure, COPD, or lung cancer. It aims to help doctors better understand and treat breathlessness.
Geneva, Canton of GenevaAges 18 years+ - NCT07291219Recruiting
Chronic heart failure patient registry study
This study creates a registry of people with chronic heart failure to track their health over time. It may help researchers learn more about the condition and improve future care.
Pavia, PaviaAges 18 years+ - NCT07284446Recruiting
Depression, memory, and outcomes in heart failure patients
This study looks at how depression and memory problems affect recovery in people hospitalized with worsening chronic heart failure. It aims to find better ways to support patients during their hospital stay.
KaunasAges 18–85 - NCT06706791RecruitingPhase 4
Empagliflozin for heart failure & diabetes: quality of life study
This trial tests whether a diabetes medicine called empagliflozin can improve the quality of life for people who have both chronic heart failure with a weak heart pump and type 2 diabetes. It compares the effects of adding empagliflozin to your current treatments.
Karachi, SindhAges 40–70 - NCT07265349RecruitingPhase 1/Phase 2
Stem cells plus bypass surgery for chronic heart failure
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07259512RecruitingPhase 4
Ramipril once or twice a day for kidney and heart health
This trial tests whether taking ramipril once or twice daily better protects kidney function in people with both chronic kidney disease (stages 3-5, not on dialysis) and heart failure with low pumping strength. It aims to find the best dosing schedule to help both organs.
Kartasura, Central JavaAges 18 years+ - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07253909Enrolling by invitation
Arm function in heart failure with ICD or CRT devices
This study looks at how well people with heart failure and certain heart devices (ICD or CRT) can use their arms and hands. It aims to understand if these devices affect upper body function.
Ankara, SamanpazarıAges 18 years+ - NCT07243119Enrolling by invitationPhase 4
Heart failure study with adenosine scans to predict recovery
This trial tests whether high-dose adenosine during a heart scan can better predict how well your heart muscle might recover, compared to standard dosing. The information could help doctors personalize treatment for people newly diagnosed with heart failure and a low ejection fraction.
HerningAges 18–100 - NCT07232030Recruiting
Barostim device for heart failure treatment
This trial tests a device called Barostim, which is implanted under the skin to stimulate nerves that help control heart failure. It's for people with mild to moderate heart failure whose symptoms are not fully controlled by medications.
Mobile, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 389 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.