Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 397 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT06270498RecruitingPhase 4
Oral iron for heart failure: exercise and quality of life study
This study tests whether an oral iron supplement (a pill called sucrosomial iron) can help people with heart failure who have low iron feel better, have more energy, and walk farther. Participants will take the iron pill or a placebo (a pill without the active ingredient) for a period and will do exercise tests and answer questionnaires to see how they improve.
Pisa, TuscanyAges 18 years+ - NCT06278844Recruiting
Pacing method to improve exercise in heart failure
This study tests a new way to pace the heart in people with heart failure who need a pacemaker. It aims to see if this pacing method helps them exercise more easily.
Edegem, AntwerpAges 18 years+ - NCT06279988Recruiting
Heart failure study for all types and stages
This study is looking at people with any type of heart failure, whether it's stable and managed at home or newly diagnosed in the hospital. The goal is to learn more about how to improve care, no matter what your ejection fraction level is.
Casale Monferrato, ALAges 18 years+ - NCT06286423RecruitingPhase 4
Colchicine for acute heart failure with low pumping strength
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
Charlottesville, VirginiaAges 18 years+ - NCT06297707Recruiting
Aquatic strength training for chronic heart failure
This trial tests whether high-intensity resistance training in water can improve strength and function in people with chronic heart failure. It's designed for those who are stable on medication and not yet in a rehab program.
Cairo, DokkiAges 45–60 - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Little Rock, ArkansasAges 18–100 - NCT06313684Recruiting
Hybrid cardiac rehab for heart failure patients
This study tests a hybrid cardiac rehab program (both at the clinic and at home) for people with heart failure. It combines supervised exercise sessions with remote support to help improve your heart health and daily function.
SantiagoAges 18 years+ - NCT06062966RecruitingPhase 1
Study of anakinra for advanced heart failure on inotrope therapy
This study tests whether a drug called anakinra can improve how your heart responds to inotrope therapy (medicines that help your heart pump). It is for people with advanced heart failure who are already on a steady dose of these medicines and have signs of inflammation. The goal is to see if blocking inflammation helps your heart work better.
Richmond, VirginiaAges 21 years+ - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT06348498RecruitingPhase 1
Jia Shen tablets for chronic heart failure study
This trial tests a Chinese herbal tablet, Jia Shen, to see how the body processes it and if it helps people with chronic heart failure. It is for adults with weak heart pumping and stable medication use.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06381427Recruiting
Improving care for older heart patients before surgery
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
GiessenAges 65 years+ - NCT06400927Recruiting
AI virtual assistant for managing new heart failure
This trial is testing a smartphone-based virtual assistant that uses artificial intelligence to help manage heart failure after you leave the hospital. It is designed for people who are newly diagnosed with heart failure and have moderate symptoms, to see if the AI assistant can help keep them healthy and out of the hospital.
Stevenage, HertfordshireAges 18 years+ - NCT06423599RecruitingPhase 2/Phase 3
Weight Loss for Obesity and Heart Failure
This study tests whether weight loss from a medication can improve how you feel, move, and how well your heart works. It's for people who have both obesity and heart failure with reduced pumping strength.
CopenhagenAges 18 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06542822Recruiting
IV iron for non-ischemic heart failure with low iron
This study tests whether intravenous iron can improve outcomes for people with non-ischemic heart failure and low ejection fraction who are also iron deficient. If you fit the criteria, you may receive iron infusions to see if it helps your heart function and symptoms.
Southampton, HampshireAges 18 years+ - NCT06545370Recruiting
Nurse Education for Heart Failure Patients and Caregivers
This trial tests whether a nurse-led education program can help people with chronic heart failure and their caregivers. You and your caregiver would learn about managing heart failure at home.
Heraklion, CreteAges 18 years+ - NCT06566911Recruiting
Voice analysis for monitoring heart failure
This trial tests if recording your voice can help doctors monitor heart failure that has suddenly gotten worse. You participate by giving voice samples, which may help find new ways to track your condition.
Rochester, MinnesotaAges 18 years+ - NCT06573892Recruiting
Gut Bacteria and Chronic Heart Failure
This study looks at how the bacteria in your gut (the microbiome) relates to chronic heart failure. Researchers want to see if certain probiotics (friendly bacteria) might help people with heart failure feel better.
AstanaAges 18 years+ - NCT06576752Recruiting
Home heart failure management after hospital discharge
This trial tests a program to manage heart failure at home after you leave the hospital. It aims to safely adjust your medications to optimal doses while you recover at home.
Lørenskog, AkershusAges 18 years+
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 397 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.