Clinical trials
Cognitive Dysfunction clinical trials
Below are recruiting cognitive dysfunction clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT03541135Enrolling by invitation
Study of heart health, diet, and activity in older adults
This study looks at heart health, food, and physical functioning in people age 65 and older living in Madrid. It may help researchers understand how lifestyle affects aging and cardiovascular wellbeing.
MadridAges 65–95 - NCT07298876Enrolling by invitation
Ultrasound for memory and sleep in early Alzheimer's
This study tests if a gentle ultrasound treatment to the brain can help improve memory and sleep quality in people with very early Alzheimer's disease. If you have mild memory issues and trouble sleeping, this low-intensity approach might be a safe option to explore.
Hong Kong, Tai Po DistrictAges 60–85 - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT07560696Recruiting
Web-based therapy for thinking and speech after illness
This study tests whether patients recovering from serious illness in the ICU or stroke ward can use a web-based platform called Cognishine to help rebuild their thinking skills and speech ability. The goal is to see if this online approach works well and is practical for patients receiving support from therapists.
LiverpoolAges 18 years+ - NCT06876597Recruiting
Robotic arm therapy for stroke recovery
This trial tests a robotic arm system that combines movement and thinking tasks to help people recover arm function after a first stroke. It is for people aged 40–80 who had a stroke within the last 2 weeks to 6 months and have some arm weakness but not too severe.
FuzhouAges 40–80 - NCT07652892Recruiting
Fatty Liver, Memory, and Health in Men and Women
This study looks at how fatty liver disease (related to metabolism) affects memory, strength, and quality of life—especially comparing men and women. It helps understand why some people with fatty liver feel more tired or have trouble thinking clearly.
Barcelona, BarcelonaAges 20–80 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT02695953Enrolling by invitation
Study brain changes after trauma-focused therapy for PTSD
This study looks at how the brain works and how it changes after Cognitive Processing Therapy (CPT) for people with PTSD. You might help researchers learn why this therapy helps and who may benefit most.
Belmont, MassachusettsAges 18–55 - NCT07622589Enrolling by invitation
How stress affects your body during market and news volatility
This study tracks how financial market changes, work stress, and news exposure affect your body's stress response using a wearable device and smartphone app. Researchers want to understand the connection between stress and physical health markers during uncertain times.
New York, New YorkAges 18 years+ - NCT06191965RecruitingPhase 2/Phase 3
MitoQ supplement for early psychosis
This study tests whether a supplement called MitoQ can help people with early-stage psychosis by improving how their cells produce energy. If you are younger and have been treated for psychosis for less than 5 years, this trial may be an option for you.
New Haven, ConnecticutAges 18–35 - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT07735078Recruiting
Smart balance and thinking exercise for older adults
This study tests a smart digital tool that combines balance and thinking exercises to help older adults stay steady and prevent falls. If you are 55+ and can walk a short distance, you may be able to join.
Taipei, TaipeiAges 55 years+ - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06782074Recruiting
Epilepsy's impact on thinking and emotions in teens
This study looks at how idiopathic generalized epilepsy affects thinking skills and emotions in adolescents aged 11 to 18. It aims to better understand these effects to improve care.
PaviaAges 11–17 - NCT06395558Recruiting
Online support program for cardiac arrest survivors
This trial tests if an internet-based program helps people recover after a cardiac arrest. You may qualify if you were discharged from the hospital with good brain function and can use the web.
Bologna, BolognaAges 18–80 - NCT05936619Recruiting
Brain-computer device for communication in people with paralysis
This trial tests a “brain-computer interface” that aims to help people with paralysis communicate. It involves surgery to place a device and uses frequent follow-ups, including daily help from a caregiver to watch the surgical area and behavior.
Dallas, TexasAges 18–65 - NCT07042633Recruiting
Gamma brain waves and memory in small vessel disease study
This study looks at how brain waves in certain areas may affect memory in people with cerebral small vessel disease. It uses EEG, a safe way to measure brain activity, along with imaging and thinking tests, to understand why some people have memory trouble.
Beijing, Beijing MunicipalityAges 55–75 - NCT06227962Enrolling by invitation
Thinking and quality of life in retinoblastoma survivors
This study looks at how retinoblastoma and its treatment affect thinking skills and quality of life over time. It may help doctors better support survivors and their families.
Amsterdam, North HollandAges 6 months–35 years - NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT06186830Recruiting
Questionnaire for jaw and face pain
This study tests a special questionnaire (BETY-BQ) to see how well it measures the impact of jaw and face pain in people with temporomandibular disorders. It helps doctors better understand your symptoms and guide treatment.
Karabük, Karabük ProvinceAges 18–64
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Common questions
- Are there clinical trials for cognitive dysfunction?
- Yes. Clin2 currently lists 145 recruiting cognitive dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.