Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,033 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07396532Recruiting
iPad messages to prevent delirium after hip fracture surgery
This trial tests if audio-recorded messages played on an iPad can help prevent confusion (delirium) after hip fracture surgery in older adults. It is for people aged 60 and older who do not have a history of memory or thinking problems.
SingaporeAges 60 years+ - NCT00768820RecruitingPhase 4
Study brain and mental health in people with 22q11 deletion
This trial looks at how thinking and mental health (psychiatric symptoms) show up in people who have a specific chromosome deletion. It may help researchers understand patterns in this condition and improve future care.
Petah TikvaAges Any age - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT01327690RecruitingEarly Phase 1
Group therapy for mental health in veterans and families
This early-stage study looks at mental health outcomes for active-duty service members, veterans, and their family members after participating in group therapy sessions. If you can follow instructions and complete consent forms, this trial may help researchers understand how group therapy affects well-being in these communities.
Santa Rosa, CaliforniaAges 18–80 - NCT00981396RecruitingEarly Phase 1
EFT therapy to help smokers who struggle to quit
This early-stage study tests Emotional Freedom Techniques (EFT), a gentle talking-and-tapping method, for people who feel very anxious about quitting and still have strong cravings. It may help improve confidence and reduce the emotional triggers that make quitting harder.
Ormskirk, LancashireAges 12–99 - NCT01635569Recruiting
Testing outcomes for children with moderate to severe OCD
This study looks at how well a treatment approach works for children and teens (ages 5–18) who have obsessive-compulsive disorder (OCD) that is moderate to severe. It may help researchers find better ways to improve symptoms and daily functioning.
Vancouver, British ColumbiaAges 5–18 - NCT02914067Recruiting
Testing brain scan and computer measures in young brain tumor patients
This study looks at “brain biomarkers,” meaning brain signals measured on MRI and thinking/learning tests on a computer. It may help researchers understand how brain tumors affect the brain and track changes over time.
St Louis, MissouriAges 4–18 - NCT02420470Recruiting
An early warning system for diabetic brain changes
This study tests whether an “early warning” approach can detect early changes in the brain related to diabetes before serious problems happen. If you qualify, you may be asked to take part in brain and health assessments to see how well the system works.
Xi'an, ShaanxiAges 40–65 - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT02434393Recruiting
Studying brain changes in late-life depression and memory decline
This study looks at how thinking and memory change in people with depression later in life, using brain imaging and related assessments. Your past participation and whether your treatments are stable enough around the time of the brain scan may determine whether you can join.
San Francisco, CaliforniaAges 65 years+ - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02752542RecruitingPhase 4
Personalized therapy and antidepressants for depression
This trial studies whether a personalized combination of talk therapy (CBT) and antidepressant medication works better for people with moderate to severe depression. It’s meant to match treatment choices to your situation and to see what helps most.
Halifax, Nova ScotiaAges 18 years+ - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT02832193Recruiting
Uses past anesthesia test data to study memory after surgery
This study looks back at information already collected around elective surgery to understand how anesthesia and surgery may affect thinking and memory (sometimes called POCD). It mainly uses records and questionnaires rather than adding a new treatment.
BerlinAges 18–100 - NCT02800395Recruiting
Study links brain changes to diet and blood markers in Alzheimer’s
This study looks at how diet-related and blood “stress” markers relate to how thinking and memory decline over time in people with Alzheimer’s. It may help researchers find useful biomarkers to better track progression and guide future care.
Pierre-BéniteAges 55 years+ - NCT03224845Recruiting
Parent and child program for anxious children
This study tests a program to help parents and young children (ages 2–8) when the child is prone to anxiety and the parent has an anxiety diagnosis. It may help families learn skills to reduce anxious feelings and improve daily functioning.
Halifax, Nova ScotiaAges Any age - NCT03184038Recruiting
Testing brain function in people with brain metastases after radiosurgery
This study looks at how well your thinking and memory work after treatment with radiosurgery for brain metastases. It may help researchers understand which patients benefit best and how to monitor side effects on brain function.
Sewell, New JerseyAges 18 years+ - NCT07158853RecruitingPhase 1
Brain stimulation and training for opioid use disorder
This trial combines a gentle brain stimulation technique called tDCS with thinking exercises to see if it helps people with opioid use disorder who are already on medication. It aims to improve treatment outcomes
Minneapolis, MinnesotaAges 18 years+ - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT07675499RecruitingPhase 2/Phase 3
Exercise and Nasal Insulin for Type 2 Diabetes
This study tests if adding nose spray insulin and exercise together improves blood sugar control and brain function in older adults with type 2 diabetes.
New Brunswick, New JerseyAges 55–80 - NCT07453537Recruiting
Cranberries and stress in healthy multitasking adults
This study tests whether cranberry polyphenols help healthy adults handle stress better during multitasking. You eat a cranberry snack and do computer tasks while your stress is measured.
Gainesville, FloridaAges 30–55 - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT02695953Enrolling by invitation
Study brain changes after trauma-focused therapy for PTSD
This study looks at how the brain works and how it changes after Cognitive Processing Therapy (CPT) for people with PTSD. You might help researchers learn why this therapy helps and who may benefit most.
Belmont, MassachusettsAges 18–55 - NCT00859794Enrolling by invitation
Study brain and movement functions in people with difficult epilepsy
This study looks at how the brain and body coordination work in people with epilepsy whose seizures do not fully respond to seizure medicines. Some participants may be people who are being evaluated for a possible epilepsy surgery because tests suggest they could benefit.
Great Neck, New YorkAges 5 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,033 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.