Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05334992Recruiting
Support for family caregivers of people with dementia
This study aims to improve mental health for people who care for someone with dementia or memory problems. If you’re an unpaid caregiver and you have anxiety or depression symptoms, this program may offer structured support to help you cope better.
Lubbock, TexasAges 18–120 - NCT05333627Recruiting
Online therapy program trial for student depression or anxiety
This trial tests an internet-based therapy program to help students with depression or anxiety. If you qualify, you’ll complete online sessions and assessments to see whether the program helps with symptoms and how long you prefer to use it.
Regina, SaskatchewanAges 18 years+ - NCT05326451Recruiting
At-home brain stimulation for Huntington’s behavior and thinking symptoms
This trial tests an at-home, noninvasive brain stimulation treatment to help with behavioral and cognitive (thinking) symptoms in people with Huntington’s disease. You and a caregiver work together during sessions and questionnaires to see if symptoms improve and stay stable.
Houston, TexasAges 18–80 - NCT05283811Recruiting
Brain recording during epilepsy care, while doing a memory task
This study listens to brain activity in people with epilepsy who already need electrodes placed inside the brain. Researchers want to understand how different parts of the brain respond while you complete simple thinking and memory-related tasks, which may help improve future treatments.
Los Angeles, CaliforniaAges 10–64 - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT05310097Recruiting
CPT therapy program with memory support for PTSD veterans
This study tests a counseling approach called Cognitive Processing Therapy (CPT) with added memory support tools. It may help reduce PTSD symptoms while also supporting day-to-day memory challenges common in PTSD.
Jamaica Plain, MassachusettsAges 18 years+ - NCT05273970Enrolling by invitation
Brain recording study during electrode surgery for drug-resistant epilepsy
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
Phoenix, ArizonaAges 18–80 - NCT05289258Recruiting
Barlow-style program for thinking and memory problems after breast cancer
This trial tests a structured “Barlow Protocol” program to help improve mild to moderate thinking and memory problems in people who finished breast cancer chemotherapy. It may help if your cognitive symptoms started after treatment and you’re not already in similar therapy.
CórdobaAges 18–70 - NCT05237986Recruiting
Study brain and thinking effects after CAR T therapy in youth
This study looks at how CAR T-cell treatment affects thinking, learning, and day-to-day brain function in children and young adults with certain blood cancers. You (and a caregiver) may complete online testing so researchers can track these changes over time and whether support is needed.
Los Angeles, CaliforniaAges 5 years+ - NCT05199896Recruiting
Brain and touch study for people with early blindness
This study looks at how the brain works when people who are blind (from birth or early childhood) touch and move. It uses an MRI brain scan to compare responses, aiming to better understand learning and brain processing in early visual loss.
BronAges 18–60 - NCT05229666Recruiting
Study stress patterns in early pregnancy and preterm birth risk
This study looks at how stress shows up in the body during early pregnancy and whether it’s linked to preterm birth (birth before 37 weeks). You may be asked about your stress and health to help researchers understand who is at higher risk.
New York, New YorkAges 18 years+ - NCT05215886Enrolling by invitation
Bariatric surgery and memory problems in people with obesity
This study looks at how bariatric (weight-loss) surgery may affect memory and thinking in people with obesity who already have memory decline or dementia. It may help doctors understand which patients benefit most and what changes to expect.
Sacramento, CaliforniaAges 18–75 - NCT05224414Recruiting
Study of how thinking styles may affect OCD treatment response
This study looks at how your interpretation of unclear situations may influence how well OCD treatment works. You’ll likely complete a computer task to understand thinking patterns and response to the main OCD study protocol.
Belmont, MassachusettsAges 18 years+ - NCT05231798RecruitingPhase 2
PET and brain scans in adults with Down syndrome
This study looks at how well a brain chemical system works in adults with Down syndrome as they age, including how it relates to Alzheimer’s-type brain changes and thinking skills. It uses brain scans and memory/thinking tests to see whether these measures can help track risk or changes over time.
Nashville, TennesseeAges 18–55 - NCT05200182Recruiting
Brain training to improve control over emotional eating
This study tests a brain training technique (neurofeedback) that may help improve self-control related to emotional eating. If you tend to eat more when stressed or upset, this could help you manage those urges.
RennesAges 18–50 - NCT05256745RecruitingPhase 1/Phase 2
A medicine to protect the heart during breast cancer chemotherapy
This early-phase study tests azeliragon to lower the risk of chemotherapy-related heart damage in women with early-stage breast cancer. Participants get their planned standard chemotherapy, plus the study medicine, and are monitored for safety and heart health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05230758RecruitingPhase 3
Metformin trial for brain tumor survivors’ brain and behavior
This Phase 3 study tests whether metformin can improve brain function, behavior, and thinking in children and teens who were treated for certain brain tumors. You may be able to join if you meet age, time-since-treatment, language, and health/lab safety requirements.
New Lambton Heights, New South WalesAges 7–21 - NCT05236010Recruiting
Brain stimulation plus cognitive training for mild TBI memory and thinking
This trial studies whether brain stimulation through the scalp can improve cognitive (thinking and memory) training in people with chronic mild traumatic brain injury (TBI). Participants train on thinking tasks while receiving a targeted “control network neuromodulation” approach to see if it enhances training results.
Minneapolis, MinnesotaAges 18–59 - NCT05194930Recruiting
Insomnia treatment study for Veterans with PTSD symptoms
This study tests treatments to help Veterans who have both PTSD symptoms and trouble sleeping (insomnia). You may be invited to try study procedures to see what helps insomnia and whether it also improves sleep-related well-being.
Sepulveda, CaliforniaAges 18 years+ - NCT05185128Recruiting
Social skills training and brain imaging in teens with autism
This study looks at how social thinking and social skills training affect the brain in teens with autism, compared with teens with other severe mental health conditions and typically developing teens. It may help researchers understand what drives social difficulties and what could improve social functioning.
Loma Linda, CaliforniaAges 12–18 - NCT05142384Recruiting
Online therapy program for mothers with depression symptoms
This study tests an internet-based cognitive behavioral therapy (an online skills-based talk therapy) to help mothers with depression symptoms. It’s offered through Head Start, where participating moms and their children connect with the program.
Springfield, OregonAges 2 years+ - NCT05151562Recruiting
Music therapy for people with early Alzheimer’s or memory loss
This trial studies whether music therapy can improve symptoms and well-being in people with early Alzheimer’s disease or mild memory problems. You may take part in music sessions and likely be screened with MRI, so the study checks safety for scans.
Baltimore, MarylandAges 18–89 - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT05129150Recruiting
Assessing brain function with an ultrasound in a day hospital
This trial studies brain function in people who are already going to a day hospital for memory and thinking assessments. It may help researchers better understand cognitive problems and improve how they are evaluated. You would likely be asked to complete an ultrasound exam of the brain and allow your information to be used for the study.
ToursAges Any age
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 1,981 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.