Clinical trials
Combination Therapy clinical trials
Below are recruiting combination therapy clinical trials, each written for real people, not researchers. We’re tracking 892 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07162246RecruitingPhase 2
Radiosurgery for large brain tumors and metastases
This trial tests a special high-dose radiation treatment for people who have up to two large brain tumors (metastases) and possibly other smaller ones. The treatment aims to control the tumors while limiting radiation to healthy brain tissue.
Toronto, OntarioAges 18 years+ - NCT07436845Recruiting
Emotion and treatment for advanced liver cancer
This trial studies if emotional health affects how well targeted therapy and immunotherapy work for people with advanced liver cancer. You will receive chemotherapy directly into the liver along with targeted drugs and immunotherapy.
Guangzhou, GuangdongAges 18 years+ - NCT06717165Recruiting
Brain stimulation with talk therapy for OCD
This study tests if adding a gentle brain stimulation technique (tACS) to cognitive behavioral therapy (CBT) can help reduce OCD symptoms more than CBT alone. It is for adults with OCD who have not completed a full course of CBT before.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07396220Enrolling by invitation
Psychotherapy with esketamine nasal spray for suicidal thoughts
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
San Diego, CaliforniaAges 18–70 - NCT07150143Recruiting
Massage and exercises for chronic neck pain
This trial tests whether adding a special type of massage (connective tissue massage) and other physical therapies to standard neck stabilization exercises helps people with long-term neck pain feel better.
Ataşehir, IstanbulAges 18–65 - NCT07720232RecruitingPhase 4
Probiotic plus lipid-lowering for pancreatitis from high triglycerides
This trial tests if adding a probiotic (Bacillus subtilis and Enterococcus faecium) to standard lipid-lowering therapy helps people with mild pancreatitis caused by very high triglycerides. It aims to see if the combination reduces inflammation and speeds recovery.
Xiamen, FujianAges 18–65 - NCT05243797RecruitingPhase 3
Teclistamab plus lenalidomide maintenance after transplant
This trial tests whether adding teclistamab to lenalidomide (or using teclistamab alone) helps keep newly diagnosed multiple myeloma from coming back after an autologous stem cell transplant. It’s comparing these options to lenalidomide alone as long-term maintenance.
Phoenix, ArizonaAges 18 years+ - NCT06277778Recruiting
Music and Taekwondo training for autistic children
This study tests whether combining music with Taekwondo training can help children with autism spectrum disorder. It aims to see if this fun activity improves their social skills and overall well-being.
Hong KongAges 7–9 - NCT06494618Recruiting
Botulinum toxin plus shockwave for leg spasticity in cerebral palsy
This study tests if combining botulinum toxin injections with radial extracorporeal shockwave therapy (RESWT) works better than injection alone for reducing leg spasticity in children with cerebral palsy. If your child has spasticity in leg muscles and is already receiving botulinum toxin, they may benefit from this additional therapy.
Istanbul, KadikoyAges 2–18 - NCT06498349Recruiting
DBS for Parkinson's impulse control problems
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
CologneAges 18–70 - NCT07080437Recruiting
Immunotherapy and chemoradiation for elderly esophageal cancer patients
This study looks at how safe and effective a combination of immunotherapy (a treatment that helps your immune system fight cancer) and standard chemotherapy plus radiation is for older adults (70+) with a type of esophageal cancer called squamous cell carcinoma who cannot have surgery or choose not to.
Chongqing, Chongqing MunicipalityAges 70 years+ - NCT07293468RecruitingPhase 2/Phase 3
Comparing two treatments for advanced liver cancer
This trial tests two different ways to treat liver cancer that can't be removed with surgery. It compares stereotactic body radiation therapy (targeted high-dose radiation) with selective internal radiation therapy (tiny radioactive beads delivered through a blood vessel), both combined with immunotherapy (medicines that help your immune system fight cancer).
Hong KongAges 18–80 - NCT07305428Recruiting
Making large liver tumors removable with immunotherapy and focused radiation
This trial tests a combination of immunotherapy and high-precision radiation (SBRT) to shrink large or multiple liver tumors in people with hepatocellular carcinoma, with the goal of making them small enough for surgery. It's for people who cannot currently have their tumors removed but might become eligible after treatment.
Hong KongAges 18–80 - NCT06911606RecruitingPhase 2
Serplulimab with chemotherapy before surgery for limited-stage small cell lung cancer
This trial tests adding an immunotherapy drug called serplulimab to standard chemotherapy before surgery for limited-stage small cell lung cancer (LS-SCLC). The goal is to see if this combination helps shrink the tumor and improve outcomes for patients who have not received prior treatment.
Guangzhou, GuangdongAges 18–75 - NCT06828380RecruitingPhase 2
Immunotherapy with or without radiation for liver cancer
This trial tests whether using immunotherapy alone works as well as immunotherapy combined with radiation for liver cancer that has spread into major blood vessels. The goal is to find the best treatment option for people with this specific type of advanced liver cancer.
GoyangAges 19 years+ - NCT06555471RecruitingPhase 2
Sintilimab plus chemo-radiation for older adults with advanced stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemoradiotherapy can help people aged 75 or older with locally advanced stomach cancer. It aims to shrink tumors and improve outcomes.
Nanjing, JiangsuAges 75 years+ - NCT06949150Recruiting
Combined heart CT scan study for coronary artery disease
This study tests a new way to use CT scans to look at both the structure of your heart arteries and how well blood flows through them. It may help doctors get a more complete picture of coronary artery disease without extra procedures.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07112911Recruiting
Electrical stimulation with robot for arm recovery after stroke
This trial tests if combining two types of electrical stimulation with a robotic device can help improve arm movement in people who had a stroke at least 6 months ago. It may be a good option if you have some movement in your arm but not full strength.
Hong KongAges 25–70 - NCT06356584RecruitingPhase 2
A drug combination with or without radiation for advanced colorectal cancer
This trial tests a new drug combo (fruquintinib and sintilimab) with or without radiation for people with colorectal cancer that has spread to the liver and has not responded to earlier treatments.
Jinan, ShandongAges 18–75 - NCT06998108RecruitingPhase 3
A new drug with fulvestrant for HR+/HER2- advanced breast cancer
This trial tests a new investigational drug called BEBT-209 combined with fulvestrant (a hormone therapy) versus placebo with fulvestrant for people with a type of breast cancer that is hormone receptor-positive and HER2-negative. It is for those whose cancer has worsened after previous hormone therapy and has spread locally or to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07495631Recruiting
Chemo + venetoclax + immunotherapy for adult ALL
This trial combines a kid-inspired chemotherapy backbone with a targeted pill (venetoclax) and immunotherapy (special antibodies) to treat adults with Ph-negative acute lymphoblastic leukemia (ALL). The goal is to use a more effective, less toxic approach developed for children.
Tianjin, Tianjin MunicipalityAges 14–60 - NCT07769827Recruiting
Peginterferon alfa-2b for advanced liver cancer with hepatitis B
This study tests a drug called peginterferon alfa-2b for people with advanced liver cancer that cannot be removed by surgery and who also have hepatitis B. The drug aims to boost the immune system to fight the cancer and may help control the disease.
Nanjing, JiangsuAges 18 years+ - NCT06826079RecruitingPhase 2
Sorbitol plus chemo and immunotherapy for advanced gastric cancer
This trial tests adding sorbitol to standard chemotherapy and an immunotherapy drug (tirellizumab) for people with locally advanced stomach cancer. The goal is to see if this combination is safe and helps shrink tumors before surgery.
Wuhan, HubeiAges 18–70 - NCT06589596RecruitingPhase 1
Study of BGB-58067 for advanced solid tumors
This trial tests an experimental drug called BGB-58067, either alone or with other cancer treatments, for people with advanced solid tumors that have stopped responding to standard therapy. It may be an option if you have a specific genetic change (loss of MTAP) in your tumor.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for combination therapy?
- Yes. Clin2 currently lists 892 recruiting combination therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a combination therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a combination therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.