Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05849025Recruiting
MRI heart study using blood-pressure and kidney checks
This study adds an MRI and other measurements to a heart registry to better understand heart function. You might benefit by getting detailed heart and kidney measurements, but you must meet safety and eligibility rules (like blood pressure, BMI, and being off heart medicines).
Rochester, MinnesotaAges 18 years+ - NCT05865119Recruiting
Best treatment approach for a certain heart wall defect
This study looks at the best treatment plan for people with a specific type of hole in the heart wall that affects the right side of the heart. It may help doctors choose an approach based on how well it works for patients who need treatment.
BordeauxAges 12 years+ - NCT06041685Recruiting
Warming for artery catheter in children under 2
This trial tests if warming the skin before placing an artery line helps children having heart surgery. It may make the procedure easier and more comfortable.
Yangsan, Gyeongsangnam-doAges Up to 2 years - NCT06075251Recruiting
Online support for parents of kids with heart conditions
This study provides an online support program for parents or caregivers of children (ages 3 to 9) who have a congenital heart condition (a heart problem present at birth). The goal is to help you and your child cope and thrive, and you can join from home if you live in Ontario.
Toronto, OntarioAges 3–9 - NCT06469918Recruiting
Support community for congenital heart defects
This trial is for people affected by congenital heart defects. It offers a support community (Co-Op) to help you connect, share, and get resources.
Rochester, MinnesotaAges birth+ - NCT06566196Recruiting
Heart exercise testing for congenital heart disease
This study tests how well your heart pumps during exercise while you are undergoing a heart catheter procedure. It may help doctors better understand your heart function and guide your treatment.
Rochester, MinnesotaAges 18 years+ - NCT06611787Recruiting
Registry study for congenital heart disease
This study collects information from people with congenital heart disease (a heart problem you're born with) over their entire life to better understand the condition and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06658496Recruiting
Studying kidney health in very premature newborns
This trial looks at how well kidneys work in very premature babies (born before 32 weeks). It uses special sensors to monitor kidney health in the first few days of life.
Madison, WisconsinAges 1 minute–1 week - NCT06668389RecruitingPhase 4
Testing a diabetes medicine for repaired tetralogy of Fallot
This study tests a type of diabetes medicine (SGLT2 inhibitor) to see if it can help people who had surgery for tetralogy of Fallot feel better and have stronger heart and lung function. It may be a good fit if you are an adult with repaired tetralogy of Fallot and do not have certain other health problems.
Hong KongAges 18 years+ - NCT06693674RecruitingPhase 3
Sacubitril-valsartan for heart health in congenital heart disease
This trial tests if a drug called sacubitril-valsartan can improve heart structure and function in adults with congenital heart disease. You will take the drug and have heart imaging to see changes.
Rochester, MinnesotaAges 18 years+ - NCT06771687Recruiting
High-intensity interval training for heart conduit patients
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart function and fitness in people who have a surgical tube (conduit) connecting their right ventricle to their pulmonary artery. It aims to find a safe and effective exercise program for those with this type of congenital heart condition.
Nijmegen, GelderlandAges 12–45 - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT06845371Recruiting
MELODY registry follow-up study
This study is for people who have already joined the MELODY registry. It will simply continue to collect information about their condition over time to help researchers better understand how things change.
TübingenAges Any age - NCT06918795Recruiting
Fontan Fitness Trial: Home exercise for better heart health
This study tests whether a home-based exercise training program can improve fitness in people with Fontan circulation. Participants will do regular aerobic exercise and be monitored for changes in heart and lung function over time.
Philadelphia, PennsylvaniaAges 10–17 - NCT07023367Recruiting
Parent navigator program for Latino families of babies with heart disease
This study offers a parent navigator program to help Latino families whose baby had early heart surgery. The program aims to support both the child's recovery and the parents' well-being.
Los Angeles, CaliforniaAges birth+ - NCT07095829Recruiting
Predicting circulation after birth for severe pulmonary valve blockage
This study looks at babies with a severe heart defect where the pulmonary valve is blocked and the wall between the heart's lower chambers is intact. It aims to predict how well blood will flow after birth using ultrasound images taken during pregnancy.
MadridAges 4 months–6 months - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT07255144Recruiting
Ultrafast ultrasound imaging for children's heart conditions
This study tests a new, faster ultrasound technique to see heart structure and blood flow in children with or without congenital heart disease (CHD). It aims to improve imaging without risk, using a short scan during a regular check-up.
Pessac, FranceAges Any age - NCT07356778RecruitingPhase 4
Study of sotatercept for Eisenmenger syndrome patients
This trial tests a new drug called sotatercept for people with Eisenmenger syndrome or a related heart defect that hasn't been repaired. It may help if current treatments aren't working well enough.
Fukuoka, Not Required For This CountryAges 18 years+ - NCT00243776Recruiting
Study of heart tissue changes during certain heart surgeries
This study collects and analyzes small samples of heart tissue during specific heart operations in babies or children. The goal is to better understand how the heart develops after birth, which could improve future care.
Atlanta, GeorgiaAges Up to 20 years - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT07405333Recruiting
Coughing exercises vs breathing device after heart surgery in children
This study compares simple coughing exercises with a breathing device (incentive spirometry) to help children recover lung function faster after heart surgery. It may help reduce complications and shorten hospital stays.
Baghdad, Baghdad GovernorateAges 6–18 - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years
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Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 186 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.