Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07559253Recruiting
Heart Care Transition Education Led by Nurses or Doctors
This study tests whether nurse-led or doctor-led education helps young people with congenital heart disease (a heart condition present from birth) transition from pediatric to adult care. The goal is to make this transition smoother and more accessible for all patients, including those with disabilities.
Madison, WisconsinAges 12–26 - NCT06747546Enrolling by invitation
Oxygen-based blood flow management after heart surgery
This study is testing a new way to manage blood flow after heart surgery in children with congenital heart disease. The goal is to make sure the body gets the right amount of oxygen to help recovery.
Minhang, Shanghai MunicipalityAges 1 week–18 years - NCT06642662Enrolling by invitation
Finding biomarkers in children after heart surgery
This study looks at proteins in the blood that may help doctors understand how children are recovering after heart surgery. It enrolls children under age 5 having certain types of heart repairs at Boston Children's Hospital.
Boston, MassachusettsAges 2 days–5 years - NCT03149341Enrolling by invitation
MRI and computer-heart simulations for heart disease
This study uses MRI scans and computer simulations to learn more about how the heart and blood flow work in people with certain heart or lung conditions. It may help researchers better understand heart problems and improve future care.
Palo Alto, CaliforniaAges Any age - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT06688396Recruiting
Finding early signs of dilated cardiomyopathy with AI and mobile screening
This trial uses a smartphone app to screen first-degree relatives of people with dilated cardiomyopathy (DCM) for early signs of the condition. It aims to detect heart muscle weakness before symptoms start, so that treatment can begin sooner.
Lancaster, PennsylvaniaAges 18 years+ - NCT07166172Recruiting
Long-term outcomes after fetal surgery for severe CDH
This study follows pregnant women and their babies after a special fetal surgery (FETO) for severe diaphragmatic hernia (CDH). It aims to understand long-term health outcomes for both mother and child.
Baltimore, MarylandAges 18 years+ - NCT02691689Recruiting
Genetics study in families with congenital heart defects and PAH
This study looks at genes that may contribute to pulmonary arterial hypertension (PAH) in people born with certain heart “shunts” (holes between heart chambers). If you have (or your family has) ASD or VSD and PAH confirmed by a heart pressure test, you may be invited to share genetic and health information to help researchers understand risk and better target future care.
LeuvenAges 18 years+ - NCT06730113Recruiting
Young adults with type 2 diabetes and heart health study
This study looks at how type 2 diabetes starting in youth affects the heart over time. It also includes teens and young adults who are overweight or lean, and their biological parents, to compare heart health across these groups.
Washington D.C., District of ColumbiaAges 12–25 - NCT07456085Enrolling by invitationPhase 3
Rivaroxaban vs warfarin for mechanical heart valves
This trial compares a newer blood thinner (rivaroxaban) to the standard one (warfarin) for people with mechanical heart valves who have had clots or bleeding while on warfarin, or who cannot easily monitor their INR levels. It aims to see if rivaroxaban is safer and more effective.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT07110389Enrolling by invitation
Heart health app program for coronary disease
This study tests a home-based cardiac rehabilitation program delivered through a smartphone app for people with coronary heart disease. If you join, you'll use the app to track your health and get support, which may help you recover and stay heart-healthy.
Taoyuan, Guishan Dist.Ages 20 years+ - NCT05895487Recruiting
UniLine heart valve replacement study for aortic or mitral disease
This trial studies how well a specific bioprosthetic heart valve (“UniLine”) works after surgery, including safety and how long it lasts. You may be able to join if you are an adult getting a first-time mitral or aortic valve replacement with this exact valve.
KemerovoAges 18 years+ - NCT03951311Recruiting
Diet and lifestyle study for people with weaker heart pumping
This study looks at how metabolic changes, diet, and lifestyle patterns affect heart failure. It may help find ways to improve symptoms and health by targeting diet and daily habits.
Shanghai, Shanghai MunicipalityAges 14–90 - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT02744677Recruiting
Pulmonary valve procedure to improve blood flow issues
This trial studies a transcatheter pulmonary valve (a valve placed through a catheter) in people whose right-sided outflow tract valve/conduit is not working well. It aims to improve blood flow and reduce pressure problems, while checking safety and results after the procedure.
Birmingham, AlabamaAges Any age - NCT07773064Recruiting
Eye scan and blood test to predict heart disease risk
This study looks at whether images of the back of your eye and certain substances in your blood can help identify people at high risk for heart disease. If you're having tests for chest pain or other heart concerns, this research may help improve early detection.
Beijing, Beijing MunicipalityAges 18–100 - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT06326996RecruitingEarly Phase 1
Thiamine before bypass surgery
This study tests if giving thiamine (vitamin B1) before heart bypass surgery can help people with low thiamine levels. It is designed for patients who are having a specific type of bypass that does not use a heart-lung machine.
Los Angeles, CaliforniaAges 60–80 - NCT06358391Recruiting
Comparing two needles for left atrial access in heart procedures
This trial compares two devices used to create a small opening in the wall between the upper chambers of the heart so doctors can reach the left side to treat heart rhythm problems or other conditions. It may help if you need a left atrial procedure and are healthy enough for the puncture.
Bucheon-siAges 18 years+ - NCT06360939Recruiting
Radiation or ablation for ventricular tachycardia in heart disease
This trial compares two treatments—radiation therapy or catheter ablation—for people with structural heart disease who have a type of fast heart rhythm called ventricular tachycardia. It aims to see which approach works better to prevent repeat episodes.
WestmeadAges 18 years+ - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90
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Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 186 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.