Clinical trials
Coronary Artery Disease (Left Main) clinical trials
Below are recruiting coronary artery disease (left main) clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07110389Enrolling by invitation
Heart health app program for coronary disease
This study tests a home-based cardiac rehabilitation program delivered through a smartphone app for people with coronary heart disease. If you join, you'll use the app to track your health and get support, which may help you recover and stay heart-healthy.
Taoyuan, Guishan Dist.Ages 20 years+ - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06985693Recruiting
AI-assisted stent placement study for heart disease
This trial tests whether a new artificial intelligence tool called Medipixel XA can help doctors place stents more precisely in blocked heart arteries. If you have coronary artery disease and need a stent, this study could be an option.
Gwangmyeong, Gyeonggi-doAges 19 years+ - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Gainesville, FloridaAges 18 years+ - NCT07022587Recruiting
Dissolving stent with drug for blocked heart arteries
This trial tests a stent that slowly dissolves after opening a blocked heart artery, releasing a drug to prevent reclogging. It may help people with narrowing in one or two spots that are not too hard or twisted.
Xi'an, ShannxiAges 18–75 - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT07004569Recruiting
Angiolite Registry Study for heart artery stents
This study is testing a new type of stent for people with a blockage in the main artery of the heart. It aims to see how well the stent works and if it's safe.
Hong Kong, ShatinAges 19 years+ - NCT07009418Recruiting
CT scan vs. usual care after heart stent or balloon treatment
This trial tests whether a CT scan of the heart arteries is a safe and effective alternative to standard follow-up tests in people who have had a stent or drug-coated balloon placed in a high-risk coronary artery. It may help reduce the need for additional invasive procedures.
Bucheon-siAges 19 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
Jonesboro, ArkansasAges 18 years+ - NCT06954714Recruiting
Balloon vs stent for new heart blockages
This trial compares two treatments for new blockages in heart arteries: a drug-coated balloon (a tiny balloon that delivers medicine) versus a drug-eluting stent (a small mesh tube that releases medicine). The study hopes to see which approach keeps the artery open longer and is safer over time.
Busan, BusanAges 19 years+ - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT06919562Recruiting
Better stent placement using imaging and newer scaffolds
This trial tests if using advanced imaging (like OCT or IVUS) to guide placement of a newer type of stent (bioresorbable scaffold) can reduce future stent problems. It is for people with stable coronary artery disease who need a stent in a main heart artery.
DordrechtAges 18 years+ - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06814587Recruiting
New imaging for heart muscle damage after a heart attack
This study uses special imaging scans (MRI and PET) to look at the health of the heart muscle in people with advanced heart failure caused by blocked arteries. The goal is to better predict recovery after bypass surgery.
Dallas, TexasAges 20–80 - NCT06779630Recruiting
Study of a 48mm drug-coated stent for long coronary artery blockages
This trial tests a longer-than-usual drug-coated stent (Orsiro Mission) for treating long blockages in heart arteries. It aims to see if the stent is safe and effective for people with coronary artery disease.
Concord, CaliforniaAges 18 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+ - NCT06710210Recruiting
Combining two heart treatments for long blocked arteries
This study tests a new way to treat long, narrow blockages in the heart's arteries. It combines a temporary scaffold with a drug-coated balloon, which may help the artery heal without a permanent metal stent. This could be an option for people who need their artery opened but may benefit from a less permanent approach.
Geneva, Canton of GenevaAges 18 years+ - NCT06657833Recruiting
Drug Balloon vs Stent for Calcified Nodules After Shockwave
This trial tests whether a drug-coated balloon (a tiny balloon that releases medicine) works as well as a drug-coated stent (a mesh tube) for treating hard calcium deposits in heart arteries. Patients first receive a special shockwave treatment to break up the calcium.
LeidenAges 18 years+ - NCT06625801Recruiting
IVUS-guided heart procedure registry for minority patients
This study is collecting information from heart procedures that use IVUS (a special ultrasound inside the blood vessels) to treat complex blockages. It aims to learn how well these procedures work in patients who identify as a racial or ethnic minority.
Phoenix, ArizonaAges 18 years+ - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06074549Recruiting
DynamX bioadaptor heart artery trial
This trial studies a new type of device called the DynamX Bioadaptor, which is placed inside a blocked heart artery to help it heal and flex naturally. It is designed for people who need a stent (a tiny tube to open a blocked artery) and may offer a more adaptive option than traditional stents.
PöltenAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease (left main)?
- Yes. Clin2 currently lists 124 recruiting coronary artery disease (left main) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease (left main) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease (left main) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.