Clinical trials
Coronary Artery Disease (Left Main) clinical trials
Below are recruiting coronary artery disease (left main) clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07182955Recruiting
Exercise training for chest pain with clear arteries
This research study looks at why people with chest pain but clear heart arteries have low fitness. It tests whether a home-based interval training program (short bursts of hard exercise) can improve fitness and quality of life.
Charlottesville, VirginiaAges 18–85 - NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07386418Recruiting
Angina thresholds study for patients needing stent treatment
This trial is testing a new way to measure blood flow in the heart during exercise to better understand angina. You may be eligible if you have at least two blocked heart arteries and are scheduled for stent placement.
BasildonAges 18 years+ - NCT07397845Recruiting
Stents vs drug-coated balloons for small or complex heart vessels
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Lucerne, Canton of LucerneAges 18 years+ - NCT01341327Recruiting
Study of treatment choices for left main artery narrowing
This observational study looks at people with a significantly narrowed “left main” heart artery and records treatment decisions and follow-up outcomes. It may help doctors better understand which care approaches work best for this condition in real-world practice.
ShanghaiAges 18 years+ - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT07444957Recruiting
Safety of a drug-coated balloon for heart artery blockages
This study tests a special balloon coated with a drug called sirolimus to open blocked heart arteries. It may be an option for people with coronary artery disease who need a less invasive treatment.
Vigo, PontevedraAges 18 years+ - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07613996Recruiting
Blood Flow Measurement During Heart Imaging
This study examines how a special measurement technique works when blood vessels are dilated during a heart imaging procedure. It may help doctors better assess whether narrowing in your heart arteries needs treatment.
Shanghai, Please SelectAges 18 years+ - NCT07110389Enrolling by invitation
Heart health app program for coronary disease
This study tests a home-based cardiac rehabilitation program delivered through a smartphone app for people with coronary heart disease. If you join, you'll use the app to track your health and get support, which may help you recover and stay heart-healthy.
Taoyuan, Guishan Dist.Ages 20 years+ - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT05865600Recruiting
PET/CT guided planning for treatment in chronic coronary disease
This trial uses a heart scan (PET/CT) to better estimate blood flow in people with long-term coronary artery disease. It aims to help doctors choose the best treatment strategy and decide who may need more invasive testing or procedures.
Herning, Central JutlandAges 18 years+ - NCT05491668Recruiting
Testing heart artery narrowing before planned stent procedure
This study checks how severely blocked a coronary artery is using measurements taken during a planned heart catheterization, to help guide whether and how to do a stent (PCI). It may help doctors choose the best treatment plan for people with about 70% or more narrowing.
Boston, MassachusettsAges 18 years+ - NCT06425120RecruitingPhase 4
Xuesaitong for heart disease risk factors
This trial tests whether Xuesaitong soft capsules can improve major risk factors in people with stable coronary heart disease who are already on cholesterol-lowering and antiplatelet medications. You may be able to join if you have chronic coronary artery disease and certain signs of inflammation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT05923489Recruiting
Follow-up angiography after stent placement in high-risk patients
This study checks how routine repeat heart blood-vessel imaging (angiography) after stent placement may help high-risk patients. It is meant for people who had a successful stent procedure and have certain higher-risk heart features.
Hangzhou, ZhejiangAges 18 years+ - NCT06168422Recruiting
Stent study for elderly with severe artery calcium
This study tests a way to open severely hardened arteries in people aged 60 and older using a special tube (stent). It may help if you have complex blockages and are a candidate for angioplasty.
Zhengzhou, HenanAges 60 years+ - NCT06657326Recruiting
New stent for high bleeding risk patients
This trial tests a new type of stent (BioFreedom Ultra) compared to a standard one (BioFreedom) in people who have a high risk of bleeding. Both stents release medicine to keep arteries open, and the study checks if the newer stent works better with a shorter course of blood thinners.
Johor Bahru, JohorAges 18 years+ - NCT07019350Recruiting
Smart stenting for heart artery branch blockages
This trial tests a new way to treat complex blockages in heart arteries where a side branch is also narrowed. It uses a drug-coated balloon to open the side branch, aiming to improve blood flow and reduce the need for repeat procedures.
GwangjuAges 19 years+ - NCT07193693Recruiting
Study on why doctors don't use heart imaging during stent placement
This study looks at reasons doctors may or may not use a special camera inside the heart arteries (called OCT or IVUS) during a procedure to open blocked arteries. It may help understand how to improve care for people with complex blockages.
BergamoAges 18 years+ - NCT05700877RecruitingPhase 4
Screening and treatment for silent heart artery disease in type 2 diabetes
This trial tests a screening and intervention approach for “silent” coronary artery disease (heart artery narrowing without major symptoms) in people with type 2 diabetes. It may help prevent future heart problems by finding higher-risk cases early and starting the right treatment plan.
OdenseAges 55–75
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Common questions
- Are there clinical trials for coronary artery disease (left main)?
- Yes. Clin2 currently lists 123 recruiting coronary artery disease (left main) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease (left main) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease (left main) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.