Clinical trials
Coronary Artery Disease (Left Main) clinical trials
Below are recruiting coronary artery disease (left main) clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
La Jolla, CaliforniaAges 18 years+ - NCT05946629Recruiting
Drug-coated stent trial for narrowed heart arteries
This trial studies a drug-coated balloon (plus standard heart medicines) to treat a specific type of blockage in the heart arteries in people who need an intervention. It may help keep the artery open and prevent the narrowing from coming back, depending on how well you match the detailed heart and medication requirements.
Jonesboro, ArkansasAges 18 years+ - NCT03587922Recruiting
Test a dissolving heart stent for blocked heart arteries
This study tests a dissolving scaffold (a type of temporary heart stent) in people with narrowed coronary arteries that are causing reduced blood flow. It aims to see if the device can be safely used as part of planned stenting or emergency bypass when needed.
ViennaAges 18 years+ - NCT04014803RecruitingPhase 4
Aspirin plus one blood thinner versus aspirin plus clopidogrel
This trial compares two common “blood thinner” combinations to prevent problems after a PCI procedure for complex blocked heart arteries. It may help your care team find which combination works better for people with higher-risk artery patterns.
SeoulAges 19–75 - NCT05292651Recruiting
Stent placement strategy study for blocked heart arteries
This study compares how best to place a coronary stent (a small tube to keep an artery open) using modern techniques. It may help improve how safely and effectively stents are delivered in people with certain types of narrowed heart arteries.
DordrechtAges 18–100 - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT05786131Recruiting
Stent treatment: fix all blocked arteries vs culprit only
This trial compares two ways of doing a stent procedure in people who had an NSTEMI heart attack: fixing all significant blockages versus fixing only the “culprit” blockage. It may help find which approach is safer and more effective for preventing complications.
GrazAges 18 years+ - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT06445608Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a temporary heart pump (called the KARDION Cory P4) used during a high-risk angioplasty (stenting) procedure. The pump helps keep blood flowing in patients whose heart is weak or who have complex blockages, aiming to make the procedure safer.
Chandler, ArizonaAges 18–90 - NCT06908499Recruiting
Long-term follow-up of a stent study for chronic total occlusions
This study looks at the long-term (10-year) outcomes of a specific stenting technique for patients with a chronic total occlusion (a complete blockage that has been there for at least 3 months) in a major heart artery. It aims to see how well the procedure works over time.
Pune, MaharashtraAges 19 years+ - NCT07610538Recruiting
Low-dose IL-2 study after heart bypass surgery
This study tests whether a low dose of a natural immune-boosting protein (IL-2) given after heart bypass surgery can help reduce heart damage. The treatment aims to activate special immune cells that protect heart tissue.
Cambridge, CambridgeshireAges 18 years+ - NCT06542575Enrolling by invitation
Home heart rehab with app after stent
This trial tests a home-based program that uses a smartphone app (digital therapy) to help people with high-risk heart conditions after a stent procedure. The goal is to improve recovery through exercise and lifestyle support, all from home.
Chengdu, SichuanAges 18–75 - NCT07035171Recruiting
Pre-surgery exercise for heart bypass patients
This study tests whether starting a supervised exercise program before your first heart bypass surgery (CABG) is possible and helpful. If you are waiting for elective CABG and speak Danish, you may be able to join a prehabilitation program to get stronger before your operation.
CopenhagenAges 18 years+ - NCT07259278Recruiting
Heart rehab program with smart app support
This trial uses a smartphone app to guide exercise for people with coronary heart disease who are at low risk of complications. It aims to help you recover safely at home with remote support from doctors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05133843Recruiting
Test heart blood-flow measurements before and after TAVI
This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.
LeipzigAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+ - NCT06275399Recruiting
Study of plaque and platelets in narrowed heart arteries
This study looks at how plaque buildup and blood platelets interact in partially blocked heart arteries. It might help find better ways to treat people with chronic coronary syndrome.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT04599192Enrolling by invitation
Test heart procedure planning in women using pressure measurements
This trial compares two strategies for deciding which heart blockages to treat, using special pressure and blood-flow measurements during a heart procedure. It may help doctors choose more accurate treatment by tailoring the plan to each person’s heart blood flow.
New Haven, ConnecticutAges 18 years+ - NCT06788275Recruiting
Can exercise improve blood vessel health after a heart attack?
This study looks at whether aerobic exercise can improve blood vessel health in people who have had a heart attack or chest pain (angina). If you qualify, you'll join a monitored exercise program.
Alicante, AlicanteAges 45–75 - NCT07587099Recruiting
Single vs. Dual Blood Thinners After Balloon Heart Treatment
This study compares whether patients who receive a special drug-coated balloon to open a blocked heart artery (without a stent) need to take one or two blood-thinning medications afterward. The goal is to find the safest and most effective approach for preventing future blockages.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65
Hear when a new Coronary Artery Disease (Left Main) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for coronary artery disease (left main)?
- Yes. Clin2 currently lists 123 recruiting coronary artery disease (left main) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease (left main) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease (left main) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.