Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06109142Recruiting
Testing a special filter to clean blood in shock and kidney failure
This trial is testing a special blood filter (oXiris) to see if it helps remove harmful substances from the blood of people in the intensive care unit with shock and kidney failure. It may help improve blood pressure and reduce the need for strong medicines.
GarchesAges 6 years+ - NCT06174610Recruiting
Kidney ultrasound for ICU patients on dialysis
This study looks at how kidney ultrasound can help monitor critically ill patients who need continuous dialysis for acute kidney injury. The results may help doctors better manage treatment.
Opole, Opole VoivodeshipAges 18 years+ - NCT06179771Recruiting
Filter during dialysis or ECMO for severe illness
This study tests a special filter (HA380 column) used during dialysis or ECMO to remove harmful substances from the blood. It is for critically ill patients with severe infection, injury, or breathing problems who also need kidney or lung support.
Leicester, LeicestershireAges 18–65 - NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Iowa City, IowaAges 19 years+ - NCT06189924Recruiting
Breath analysis in ventilated ICU patients
This study collects and analyzes the moisture you breathe out while on a ventilator in the ICU. It aims to learn more about your condition by examining your breath.
OlomoucAges 18 years+ - NCT06193980Recruiting
ICU recovery exercise test study
This trial looks at how well your heart and lungs work together after a long stay in the ICU on a breathing machine. It uses a simple exercise test to check your recovery after leaving the hospital.
Winnipeg, ManitobaAges 18 years+ - NCT06208332RecruitingPhase 2
Communication support for kids with severe neurological needs
This study tests a new communication program to help families and doctors talk about what matters most to your child with a severe neurological condition. It is for hospitalized children ages 6 months to 25 years old, who have had their condition for more than 6 months.
Seattle, WashingtonAges 6 months+ - NCT06294158Recruiting
Light and noise in the ICU and delirium risk
This study looks at how light and noise in the intensive care unit (ICU) might affect confusion and disorientation (delirium). By tracking these environmental factors, researchers hope to find ways to reduce delirium for ICU patients.
Graz, StyriaAges 18 years+ - NCT06323226Recruiting
Sepsis long-term outcomes in critically ill children
This study looks at how sepsis (a severe infection that can affect the whole body) affects children after they leave the intensive care unit. It compares children who had sepsis to those with other critical illnesses to understand long-term health.
Chengdu, SichuanAges birth–16 years - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06341972Recruiting
Recovering after breathing support: a self-help program
This study tests a self-management program to help people who felt anxious after being on a breathing machine in the ICU. It aims to improve emotional recovery and quality of life.
Baltimore, MarylandAges 18 years+ - NCT06357403Recruiting
Predicting blood clots in ICU patients with a blood test
This study looks at whether a blood test measuring a substance called anti-factor Xa activity can help predict dangerous blood clots in critically ill patients. If you join, researchers will follow you to see if the test results can prevent clots.
Graz, StyriaAges 18 years+ - NCT06362525Recruiting
Episodes of Disconnected Consciousness in Emergency Patients
This study looks at brief episodes of being disconnected from your surroundings among very ill emergency patients. Researchers want to see how often this happens and what it means for recovery.
LiègeAges 18 years+ - NCT06369818Recruiting
Heart output measurement in shock patients on life support
This study tests if a new way of measuring heart function (using sound waves and breath analysis) works well in patients who are in severe heart failure and need a heart-lung machine. It might help doctors better monitor patients after heart surgery.
MünsterAges 18 years+ - NCT06386796Recruiting
Using ultrasound to predict kidney trouble in high-risk patients
This study uses a simple ultrasound test (kidney artery scan) to see if it can predict kidney problems early in people who are very ill. It may help doctors protect your kidneys during your hospital stay.
Aswān, Aswan GovernorateAges 18–80 - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06427265Recruiting
Recovery after ICU: a long-term study
This study follows people after they leave the ICU to see how they recover over time. It uses computer programs to find patterns and create early warning tools to help doctors spot problems sooner.
Guiyang, GuizhouAges 18–100 - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06452966Recruiting
Traditional Chinese medicine for organ failure in ICU
This trial is studying whether adding traditional Chinese medicine (TCM) to standard care can help patients in the surgical ICU recover from organ failure. It looks at how TCM might support your body's organs during critical illness.
TaichungAges 20 years+ - NCT06460363Recruiting
Electrical brain stimulation for delirium in ICU patients
This trial tests whether a gentle electrical current applied to the scalp can help treat delirium (sudden confusion) in intensive care patients. It aims to improve recovery in people who have had confusion for more than 24 hours.
KuopioAges 18 years+ - NCT06471400Recruiting
Making clinical trial consent easier for legal representatives
This trial is designed to improve how legally authorized representatives (people who make medical decisions for patients) understand and agree to join clinical studies. The goal is to see if simpler consent processes help representatives feel more comfortable giving permission.
Freiburg im BreisgauAges 18–100 - NCT06472999Recruiting
Kidney protection in critically ill ICU patients
This trial tests ways to protect the kidneys in intensive-care patients who have moderate or severe acute kidney injury. If you are on a ventilator or medications to support blood pressure, this study may offer extra kidney care to help prevent further damage.
InnsbruckAges 18 years+ - NCT06473415Recruiting
Lormetazepam for sleep in the ICU
This trial tests whether a sleep medication called lormetazepam can improve sleep quality and brain activity in ICU patients who are on a breathing machine. It may help if you need sedation and are expected to stay in the ICU for at least two days.
Mitte, State of BerlinAges 18–100
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 352 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.