Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06513130Recruiting
Checkup after ICU for adults 75 and older
This study looks at how well older adults (75+) do after leaving the intensive care unit. It will test a simple checkup done at discharge to see if it helps doctors plan better care.
StrasbourgAges 75 years+ - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT04705896RecruitingPhase 4
Albumin for kidney recovery after ICU kidney injury
This trial tests whether giving albumin (a blood protein through an IV) can improve recovery after acute kidney injury in people who are in the ICU and need kidney support treatment. It mainly aims to help the kidneys bounce back better after this serious illness.
Calgary, AlbertaAges 18 years+ - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT07143695Recruiting
Chest muscle ultrasound to guide breathing machine weaning
This study uses an ultrasound to measure how well a chest muscle moves when you try to breathe on your own. It may help doctors decide if you are ready to come off the breathing machine.
Cairo, Giza GovernorateAges 18–65 - NCT07141420Enrolling by invitation
Smartphone tool to help ICU recovery
This study tests whether a smartphone tool can help people recover from the long-term effects of being in the ICU. You might be eligible if you had a recent ICU stay and are comfortable using a smartphone.
Guiyang, GuizhouAges 18–100 - NCT07130799Recruiting
Monitoring immune response in severe abdominal infections with fungal risk
This trial monitors a marker of immune function (monocyte HLA-DR) in patients with severe abdominal infections that may lead to fungal infections. It aims to see if this marker can help guide treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18 - NCT07125079Recruiting
Studying immune cells and a new treatment for ARDS
This study looks at how the immune system responds in people with ARDS (a severe lung injury) and tests a new treatment called PIP-2 in the lab to see if it might help. It aims to better understand lung injury and find new ways to treat it.
Philadelphia, PennsylvaniaAges 21–90 - NCT07124442Recruiting
Muscle function study for ICU patients
This study looks at muscle function and disease severity in people who have been in the intensive care unit (ICU) for at least 48 hours. It aims to understand how muscle problems relate to recovery and risk, without requiring a breathing machine.
Istanbul, EsenyurtAges 18 years+ - NCT07118384Recruiting
Comparing two antibiotics for drug-resistant infections
This trial tests two different antibiotic combinations (ampicillin/sulbactam and cefoperazone/sulbactam) to see which works better against a type of bacteria (Acinetobacter baumannii) that is resistant to many other drugs. It is for critically ill patients with signs of sepsis.
CairoAges 21 years+ - NCT07110129Recruiting
Testing a new tool to see if you're ready to come off the breathing machine
This study tests a new way to check if your breathing muscles are strong enough to safely remove the breathing tube. It uses a special patch to measure how well your diaphragm works, which may help doctors make better decisions about when to take the tube out.
CardiffAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT06966869Recruiting
Fentanyl patch absorption in ICU patients
This study looks at how well fentanyl patches work in ICU patients who are not stable. It aims to understand if the patch is absorbed properly in these patients.
Tel Aviv, IsraelAges 18–70 - NCT03822949Recruiting
Bright light exposure during heart surgery for better recovery
This trial tests whether using bright light at the right time during and after heart surgery helps patients recover more comfortably. It focuses on people having a specific type of open-heart surgery and checks certain heart rhythm and safety factors.
Denver, ColoradoAges 18–90 - NCT07094425Recruiting
Heart function study for ICU patients on breathing machines
This study looks at how the heart is affected in critically ill patients who need a breathing machine. It uses ultrasound and other simple tests to check for heart problems that can happen in the ICU, which may help doctors find and treat them earlier.
Vienna, State of ViennaAges 18 years+ - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07074028Recruiting
Tracking muscle changes in ICU patients with sepsis
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Saint-BrieucAges 18 years+ - NCT07048951Recruiting
Memory and awareness after ICU: understanding moments of disconnect
This trial studies episodes of lost or altered consciousness that some people experience after a long stay in the ICU. It aims to understand how these episodes affect memory and recovery.
Liège, LiègeAges 18 years+ - NCT07052123Recruiting
Blood pressure monitoring in ICU with DARE device
This trial tests a new non-invasive device (DARE) to measure blood pressure and core body temperature in patients who are already receiving standard monitoring with an arterial line and a urinary catheter in the ICU.
Saint-Denis, FranceAges 18 years+ - NCT06991777Recruiting
Precision sedation in the ICU
This trial tests a precise way to manage sedation for intensive care patients who need it for more than 24 hours. It aims to improve recovery and reduce side effects.
Oslo, OsloAges 18 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 336 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.