Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06557629Recruiting
Gastric sonar vs aspiration for feeding tube placement in ICU
This trial tests whether using a special ultrasound device (gastric sonar) to check stomach contents is as good as the standard method of suctioning stomach fluid to make sure feeding tubes are in the right place in critically ill patients.
Kfar SabaAges 18–99 - NCT03629977Recruiting
Timing dialysis in critically ill ICU patients
This study looks at the best timing for starting kidney support treatment (dialysis) in very sick people in the ICU. It may help improve outcomes by comparing different start times.
StockholmAges 18 years+ - NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT06543602Recruiting
Monitoring agitation in ICU patients with a video camera
This trial uses a special camera to monitor ICU patients who may become agitated. By watching your face and body movements, doctors hope to detect agitation early and improve your care.
Hangzhou, ZhejiangAges 18–65 - NCT07101640RecruitingPhase 1/Phase 2
Montelukast study for breathing problems in premature infants
This trial tests if the medicine montelukast can help very premature babies on breathing machines. It aims to see if it improves lung development and makes it easier for them to breathe on their own.
Little Rock, ArkansasAges 1 week–4 weeks - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT06510348Recruiting
Feeding support for ventilated patients with gut issues
This trial tests a special approach to nutrition for patients on breathing machines who have trouble digesting food. It aims to see if the new method helps meet nutritional needs better.
BucharestAges 18 years+ - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT07312708Recruiting
Protein dosing in ICU patients: weight vs. muscle mass
This trial compares two methods for calculating protein doses in critically ill patients: using actual body weight versus fat-free mass. It aims to find which approach is better for recovery in the ICU.
EdeAges 18 years+ - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90 - NCT07732114Recruiting
Liver vein vs. heart echo to check right heart function on a ventilator
This study compares a liver vein ultrasound method with a standard heart ultrasound for checking how well the right side of the heart is pumping in patients who are on a breathing machine (ventilator). If you are on a ventilator and can get a clear ultrasound of your heart and liver veins, you may be able to join.
Alexandria, Shebin El-KomAges 18 years+ - NCT04875260Recruiting
Carefully compare outcomes in ICU patients
This study focuses on critically ill people in the intensive care unit (ICU). It aims to learn what affects outcomes and resources, which may help improve how care is planned for ICU patients.
DouliuAges 20 years+ - NCT06234787Recruiting
Continuous glucose monitoring in ICU patients
This study looks at how well continuous glucose monitors (small sensors under the skin that track sugar levels) work in ICU patients who need insulin. If you are in the ICU, on insulin, and already have a sensor, you may be able to join.
MadridAges 18 years+ - NCT07275658Recruiting
Timing and dose of fluid removal in ICU patients
This study tests when and how much fluid should be removed from patients in the intensive care unit (ICU) who need help getting rid of extra fluid. It uses medicines called diuretics or a machine that filters the blood (ultrafiltration) to find the best approach.
AmsterdamAges 18 years+ - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT05587517RecruitingPhase 2
Support for family decision-makers of critically ill patients
This Phase 2 study tests interventions to support family surrogate decision-makers when a loved one is very sick in the ICU and is nearing end-of-life. It may help by reducing distress and pre-loss grief through structured support delivered by phone or video.
Miami, FloridaAges 18 years+ - NCT06960642Recruiting
Dosage of Early Rehab for ICU Patients
This trial tests different amounts of early physical therapy for patients in the intensive care unit (ICU). The goal is to find out how much rehabilitation is best for recovery.
Vienna, State of ViennaAges 18 years+ - NCT07143084Enrolling by invitation
Nutrition and frailty in ICU patients over 65
This study looks at how nutrition relates to frailty in older adults staying in the intensive care unit (ICU). It may help find better ways to support recovery.
Altındağ, AnkaraAges 65 years+ - NCT06223828RecruitingPhase 2/Phase 3
Azithromycin for Children with Severe Asthma in the ICU
This trial tests whether adding the antibiotic azithromycin to standard asthma treatments helps children with severe asthma in the pediatric intensive care unit (PICU) recover faster. It is for children ages 3 to 17 who are already receiving strong asthma medicines and steroids.
St. Petersburg, FloridaAges 3–17 - NCT02766166Recruiting
Study of health status scores in monitored hospital patients
This study looks at how a “health score” measures a patient’s condition and outcomes while they are in the hospital with heart monitoring. It may help doctors better assess risk and track how patients do over time.
Indianapolis, IndianaAges 18 years+ - NCT06728722Recruiting
Ultrasound for body measurement in critical care
This study uses ultrasound to measure body composition in women admitted to the Obstetrics and Gynecology critical care unit. It aims to see if ultrasound can help assess health status in critically ill patients.
Cairo, Cairo GovernorateAges 16 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 352 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.