Clinical trials
Decompensated Heart Failure clinical trials
Below are recruiting decompensated heart failure clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06414759RecruitingPhase 4
Combination diuretic therapy for heart failure fluid overload
This trial tests a combination of water pills (diuretics) to help remove extra fluid in people hospitalized with acute decompensated heart failure (sudden worsening of heart failure). It aims to find a safe and effective way to reduce swelling and fluid buildup.
Giza, GZAges 18–65 - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT06475105RecruitingPhase 4
Acetazolamide and Furosemide for Acute Heart Failure
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Semarang, Central JavaAges 18 years+ - NCT06528561Recruiting
Exercise program for hospitalized heart failure patients
This trial tests whether a physical exercise program can help people in the hospital with worsening heart failure improve their ability to take care of themselves. If you are admitted for heart failure and can safely walk or move, this program may help you get stronger before you go home.
PortoAges 18 years+ - NCT06532825Recruiting
Nerve function test in advanced heart failure
This study looks at how the nervous system controls the heart in people with advanced heart failure. It may help doctors understand which patients are unlikely to recover, so they can plan the best care.
FrederiksbergAges 18 years+ - NCT06535529RecruitingPhase 3
Comparing Two Water Pills for Worsening Heart Failure
This study compares two medicines—acetazolamide and dapagliflozin—to see which works better at removing extra fluid in people hospitalized for worsening heart failure. It may help decide the best treatment for fluid overload.
CairoAges 18 years+ - NCT06555757Recruiting
Using AI and sound to predict heart failure worsening
This trial uses a smartphone app to record sounds from your chest and breathing. An AI system will analyze these sound patterns to predict when heart failure symptoms might get worse, so you can get help sooner.
Cambridge, CambridgeshireAges 18 years+ - NCT06566911Recruiting
Voice analysis for monitoring heart failure
This trial tests if recording your voice can help doctors monitor heart failure that has suddenly gotten worse. You participate by giving voice samples, which may help find new ways to track your condition.
Rochester, MinnesotaAges 18 years+ - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06586008Recruiting
Heart failure ultrasound and recovery study
This trial uses a special ultrasound scoring system to see how well people with a certain type of heart failure (weak heart pumping) are doing. It looks at whether this score can predict how their recovery goes.
Semarang, Central of JavaAges 18–70 - NCT06628973Recruiting
Social activities for women with heart failure
This trial tests a social program to help women with heart failure better stick with their medications and feel healthier. You'll be connected to community activities and support tailored to your needs.
Montreal, QuebecAges 18 years+ - NCT06630923RecruitingPhase 3
Preventing kidney worsening with IV albumin in heart failure
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Alexandroupoli, EvrosAges 18–95 - NCT06652763Recruiting
MRI scan for heart failure with normal pumping strength
This study uses a special MRI scan with a natural contrast agent (manganese) to look at how well the heart muscle works in people with heart failure who still have normal pumping strength. The goal is to learn more about why this type of heart failure happens.
LeicesterAges 18 years+ - NCT06656832Recruiting
How Heart Failure Progresses in Hospitalized Patients
This study looks at why heart failure gets worse over time. It involves people who have been hospitalized for heart failure and have a known heart abnormality. Doctors will monitor your health to find clues about disease progression.
LeipzigAges 18 years+ - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06819618Recruiting
Predicting heart failure outcomes with machine learning
This trial uses machine learning to analyze data from a smartwatch to predict how heart failure progresses. It may help doctors better understand your condition and tailor treatments.
Goettigen, Lower SaxonyAges 18 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06898515RecruitingPhase 3
Fluid removal study for acute heart failure patients
This trial tests a device designed to safely remove extra fluid from patients hospitalized with worsening heart failure. It may help those who are not responding well to standard water pills (diuretics).
Irvine, CaliforniaAges 22 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07038356RecruitingPhase 3
Continuing empagliflozin for heart failure patients in hospital
This trial tests whether staying on the medication empagliflozin helps people with heart failure who are hospitalized for worsening symptoms. Empagliflozin is a type of drug called an SGLT2 inhibitor, which helps control blood sugar and protect the heart.
Jena, ThuringiaAges 18 years+ - NCT07099885Recruiting
Urine test to guide water pill treatment for heart failure
This study tests a simple urine test to help doctors choose the best dose of water pills (diuretics) for people hospitalized with heart failure and leg swelling. The goal is to relieve congestion faster and more safely.
Wroclaw, DolnosląskieAges 18 years+ - NCT07173426Recruiting
Using bioimpedance to guide fluid therapy in heart failure
This study tests a new way to manage fluid buildup in patients hospitalized with worsening heart failure. It uses a simple, non-invasive tool (‘bioimpedance’) to help doctors better balance your fluids, which could help you feel better and recover faster.
Basildon, EssexAges 18 years+
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Common questions
- Are there clinical trials for decompensated heart failure?
- Yes. Clin2 currently lists 163 recruiting decompensated heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a decompensated heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a decompensated heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.