Clinical trials
Decompensated Heart Failure clinical trials
Below are recruiting decompensated heart failure clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06819618Recruiting
Predicting heart failure outcomes with machine learning
This trial uses machine learning to analyze data from a smartwatch to predict how heart failure progresses. It may help doctors better understand your condition and tailor treatments.
Goettigen, Lower SaxonyAges 18 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07099885Recruiting
Urine test to guide water pill treatment for heart failure
This study tests a simple urine test to help doctors choose the best dose of water pills (diuretics) for people hospitalized with heart failure and leg swelling. The goal is to relieve congestion faster and more safely.
Wroclaw, DolnosląskieAges 18 years+ - NCT07173426Recruiting
Using bioimpedance to guide fluid therapy in heart failure
This study tests a new way to manage fluid buildup in patients hospitalized with worsening heart failure. It uses a simple, non-invasive tool (‘bioimpedance’) to help doctors better balance your fluids, which could help you feel better and recover faster.
Basildon, EssexAges 18 years+ - NCT07199088Recruiting
Comparing two medicines for fluid buildup in heart failure
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 18 years+ - NCT07205120Recruiting
Fluid-guided heart failure treatment study
This trial tests a new way to manage fluid levels in people hospitalized for heart failure. It aims to help doctors adjust treatment to keep you from coming back to the hospital.
Cleveland, OhioAges 21 years+ - NCT07218627RecruitingPhase 1
Study of New Drug for Heart Failure
This study tests a new medication called NNC0537-1482 for people with heart failure. It aims to see if the drug is safe and how it affects the body, and may help improve symptoms.
LondonAges 40–75 - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Birmingham, AlabamaAges 18–99 - NCT07263035RecruitingPhase 4
Urine sodium-guided diuretic strategy for heart failure
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
Lakeland, FloridaAges 18 years+ - NCT07350759Recruiting
Using a wearable to detect heart failure worsening
This study tests if a wearable device can spot early signs of heart failure getting worse. If you already use a heart monitor and have stable readings, you may help show how a non-invasive wearable could alert you sooner.
Tampa, FloridaAges 18 years+ - NCT07373041Recruiting
Support program for heart failure carers in the UK
This study tests a support program for people who care for loved ones with heart failure. It aims to see if the program helps carers by providing talking support and information, and it may help you if you’re caring for someone with heart failure and are comfortable using a digital device.
BelfastAges 18 years+ - NCT00762008Recruiting
Test blood markers to understand progression to heart failure
This study looks at blood “markers” (substances in the blood) to help explain how some people move from early heart strain to full heart failure. You may be enrolled if you have stable or worsening heart failure symptoms, or you may qualify as a healthy control for comparison.
Farmington, ConnecticutAges 18 years+ - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+ - NCT07419360Recruiting
Draining fluid from lungs in heart failure
This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.
Albany, New YorkAges 18 years+ - NCT07439159Recruiting
Heart ultrasound to predict outcomes in hospitalized heart failure
This study uses a heart ultrasound (echocardiogram) to predict outcomes in people hospitalized for sudden heart failure. If you are receiving IV fluid-removing medication, the results may help your doctors understand your condition better.
IstanbulAges 18 years+ - NCT07444398RecruitingPhase 1
Vericiguat for worsening heart failure
This trial tests if adding vericiguat to standard heart failure medicines helps people hospitalized with worsening heart failure. It's for those with a weak heart pump and high NT-proBNP levels.
Rawalpindi, Punjab ProvinceAges 25–65 - NCT07472660Recruiting
Web-based prevention program after heart failure hospitalization
This trial tests a web-based prevention program for people recently hospitalized with heart failure (with low pumping ability). The goal is to help you stay healthier and avoid another hospital stay.
BremenAges 18–80 - NCT07508891Recruiting
Studying heart failure types in hospitalized patients
This trial looks at different types of acute heart failure in people who are hospitalized. Doctors will study your symptoms and health to better understand heart failure patterns, which might help improve future treatments.
HamburgAges 18 years+ - NCT07527156RecruitingPhase 4
Ketones through a nose tube for severe heart failure
This trial tests whether giving a special liquid diet (ketones) through a thin tube in your nose helps your heart pump better when it's severely weakened and not getting enough blood to your body. Ketones are an alternative fuel your body can use instead of glucose.
Prague, PragueAges 18 years+ - NCT07544771Recruiting
HeartLogic monitoring in heart failure patients
This study tests whether a special monitoring system in your heart device (called HeartLogic) can help detect early warning signs of heart failure getting worse. It uses wireless check-ins to track your condition at home and alert your doctor if you need help.
AmiensAges 18 years+ - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+
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Common questions
- Are there clinical trials for decompensated heart failure?
- Yes. Clin2 currently lists 162 recruiting decompensated heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a decompensated heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a decompensated heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.