Clinical trials
Decompensated Heart Failure clinical trials
Below are recruiting decompensated heart failure clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+ - NCT06656832Recruiting
How Heart Failure Progresses in Hospitalized Patients
This study looks at why heart failure gets worse over time. It involves people who have been hospitalized for heart failure and have a known heart abnormality. Doctors will monitor your health to find clues about disease progression.
LeipzigAges 18 years+ - NCT06652763Recruiting
MRI scan for heart failure with normal pumping strength
This study uses a special MRI scan with a natural contrast agent (manganese) to look at how well the heart muscle works in people with heart failure who still have normal pumping strength. The goal is to learn more about why this type of heart failure happens.
LeicesterAges 18 years+ - NCT06628973Recruiting
Social activities for women with heart failure
This trial tests a social program to help women with heart failure better stick with their medications and feel healthier. You'll be connected to community activities and support tailored to your needs.
Montreal, QuebecAges 18 years+ - NCT06555757Recruiting
Using AI and sound to predict heart failure worsening
This trial uses a smartphone app to record sounds from your chest and breathing. An AI system will analyze these sound patterns to predict when heart failure symptoms might get worse, so you can get help sooner.
Cambridge, CambridgeshireAges 18 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06299436Recruiting
Heart muscle function testing in right heart failure
This trial studies how the right side of the heart works in people with heart failure. It uses special monitoring to understand muscle function and may help doctors find better ways to treat right heart failure.
Baltimore, MarylandAges 18–90 - NCT06205225Recruiting
Mobile health program for heart failure self-care
This study tests a mobile health program (phone app and coaching) to help people with heart failure better manage their condition at home. It aims to improve self-care and reduce hospital visits.
Chicago, IllinoisAges 18 years+ - NCT06176131Recruiting
Telemedicine support for heart failure after hospital
This study tests a care program that uses telemedicine to help people with serious heart failure stay stable after leaving the hospital. It focuses on those who needed multiple hospital stays recently.
FrederiksbergAges Any age - NCT06081543Recruiting
Ketogenic vs. Mixed Diet for Heart Failure
This study compares a ketogenic (low-carb, high-fat) diet to a standard mixed diet in people with heart failure. It aims to see if the ketogenic diet can improve heart function and symptoms.
Columbus, OhioAges 18–80 - NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05784753Recruiting
Exercise coaching for adults with heart failure and preserved heart strength
This study tests an exercise-focused program (including coaching/support) for adults with heart failure where the pumping strength is preserved. It may help improve exercise ability and daily function while monitoring safety.
Detroit, MichiganAges 18 years+ - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT05677100Recruiting
Aortix device for acute heart failure
This trial is testing a small pump placed in the aorta to help the kidneys remove extra fluid when standard IV diuretics aren't working well enough for severe heart failure. It may help you if you're hospitalized and still very congested (swollen, fluid buildup) despite strong water pills.
Phoenix, ArizonaAges 21 years+ - NCT05585125RecruitingPhase 4
Testing an informed approach for older adults with HFpEF
This study looks at an “informed” approach to help manage HFpEF (a type of heart failure) in people age 65 and older. It checks whether a structured plan and monitoring are practical and safe for you over time.
New York, New YorkAges 65 years+ - NCT05577819Recruiting
Screening for ATTR heart amyloid in older HFpEF patients
This study looks at how often a specific heart condition (ATTR amyloid) occurs in people age 65+ who have HFpEF. It also tries to predict who might have it, using a special heart scan, and may help your care team identify it earlier.
Boston, MassachusettsAges 65 years+ - NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05417490Recruiting
Study of why people join PRADO and telemedicine for heart failure
This study looks at what influences whether people with heart failure choose to join PRADO and telemedicine support after a hospital stay. Your answers can help the team understand barriers and improve future participation and care.
MontpellierAges 18 years+ - NCT02973633RecruitingEarly Phase 1
Heart failure MRI brain-wave images after heart trouble
This early-phase study uses a special MRI scan to look at the heart in people with heart failure (and related heart changes). It aims to see whether these MRI results can better characterize heart disease and help doctors understand what’s going on.
Charlestown, MassachusettsAges 18–85 - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT03586336Recruiting
Remote lung fluid monitoring to guide heart failure treatment
This study tests a wearable vest that measures fluid in your lungs to help doctors adjust water-pill treatments for heart failure. It aims to reduce hospital stay and improve recovery.
San Francisco, CaliforniaAges 18 years+ - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+
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Common questions
- Are there clinical trials for decompensated heart failure?
- Yes. Clin2 currently lists 152 recruiting decompensated heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a decompensated heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a decompensated heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.