Clinical trials · Atlanta, GA
Depression clinical trials in Atlanta
We’re tracking 46 recruiting depression studies with a site in or near Atlanta — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Atlanta
- NCT05849038RecruitingPhase 2
Treating inflammation to improve depression in HIV
This Phase 2 study looks at whether lowering inflammation can help improve depression symptoms in adults living with HIV. You may be able to join if your HIV is well controlled and you are currently experiencing major depression (or a certain type of bipolar depression).
Atlanta, GeorgiaAges 18–65 - NCT06966401RecruitingPhase 3
Long-term safety study of a new depression treatment
This study tests a new oral medication (NBI-1065845) added to your current antidepressant to see if it's safe and tolerable over a long period for people with depression that hasn't fully responded to treatment.
Atlanta, GeorgiaAges 18 years+ - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Atlanta, GeorgiaAges 18–74 - NCT07172516RecruitingPhase 3
Study of azetukalner vs placebo for bipolar depression
This trial tests whether the study drug azetukalner can help reduce depression symptoms in people with bipolar I or II disorder who are currently having a depressive episode. You would be randomly assigned to receive either the drug or a placebo (inactive pill) to see which works better.
Atlanta, GeorgiaAges 18–74 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT04099056Recruiting
Brain scanning and stimulation to study decision-making
This trial uses brain scans and noninvasive brain stimulation to study how people make decisions. It may help researchers understand brain signals involved in choices and potentially improve future treatments.
Atlanta, GeorgiaAges 18–50 - NCT05327699RecruitingEarly Phase 1
Ketamine study for depression with reduced pleasure
This early-phase study tests whether ketamine can help people with major depression who have trouble feeling pleasure. It also studies how the brain may change in response to stress, to better understand who might respond to treatment.
Atlanta, GeorgiaAges 18–65 - NCT06775379RecruitingPhase 3
Azetukalner vs. placebo for major depression
This trial tests an investigational medication called Azetukalner against a placebo to see if it helps reduce symptoms of major depressive disorder. You may qualify if you are currently in a depressive episode that started in adulthood and have not tried or failed only a few antidepressants.
Atlanta, GeorgiaAges 18–74 - NCT07217860Enrolling by invitationPhase 3
Long-term safety study of azetukalner for bipolar depression
This study is looking at the long-term safety of azetukalner for people with bipolar I or II depression who have already completed a previous trial of this drug. It is an open-label study, meaning everyone will receive the active medication.
Atlanta, GeorgiaAges 18–75 - NCT07553637RecruitingPhase 2
ALTO-207 for Adults With Hard-to-Treat Depression
This study tests whether a new medication called ALTO-207 can help people with depression that hasn't improved with standard antidepressants. You may qualify if you've tried multiple antidepressants without enough relief and are willing to add this experimental treatment to your current medication.
Atlanta, GeorgiaAges 18–75 - NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Atlanta, GeorgiaAges 18 years+ - NCT06372964RecruitingPhase 3
Lumateperone for pediatric bipolar depression
This study tests a new medication called lumateperone for treating depression in children and teens with bipolar disorder. It aims to see if this drug can help improve mood and daily functioning.
Atlanta, GeorgiaAges 10–17 - NCT06656416RecruitingPhase 2
ALTO-100 for bipolar depression
This trial tests an investigational drug called ALTO-100 in people with bipolar I or II who are currently experiencing depression. It looks at whether this new medicine can help improve depression symptoms when taken alongside your usual mood stabilizer or antipsychotic medication.
Atlanta, GeorgiaAges 18–70 - NCT07003997RecruitingPhase 2
JAK inhibitor for depression with inflammation
This trial tests a JAK inhibitor (a type of anti-inflammatory drug) for depression that is linked to inflammation. If you have depression or bipolar depression and a high CRP level (a marker of inflammation), you may be eligible.
Atlanta, GeorgiaAges 25–55 - NCT06911112RecruitingPhase 3
A new pill for depression when current treatment isn't working well enough
This trial tests an investigational medication (NBI-1065845) added to your current antidepressant to see if it can improve depressive symptoms. It is for people with moderate to severe depression who have not fully responded to their current antidepressant.
Atlanta, GeorgiaAges 18 years+ - NCT06922110Enrolling by invitationPhase 3
Long-term study of azetukalner for depression
This study is for people who already completed a previous trial of azetukalner for major depressive disorder. It tests the long-term safety and effects of continuing the medication.
Atlanta, GeorgiaAges 18 years+ - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Atlanta, GeorgiaAges 18–50 - NCT07076407RecruitingPhase 3
Testing a new antidepressant pill for depression
This study tests an experimental oral pill called azetukalner against a placebo to see if it safely reduces symptoms of major depressive disorder. It is for adults who are currently in a depressive episode lasting 6 weeks to 2 years and have not already tried multiple antidepressants that failed.
Atlanta, GeorgiaAges 18–74 - NCT06580145RecruitingPhase 2
Leucine for midlife depression
This study tests whether leucine, a common amino acid supplement, can help treat moderate to severe depression in people aged 40–65. You'll have blood tests, an MRI, and a lumbar puncture to measure changes in your brain.
Atlanta, GeorgiaAges 35–65 - NCT06633016RecruitingPhase 2
ABX-002 for major depression (add-on treatment)
This trial tests a new medication called ABX-002 as an add-on to your current antidepressant. It's for people with moderate to severe depression who haven't gotten enough help from their current antidepressant alone.
Atlanta, GeorgiaAges 18–65 - NCT07276997RecruitingPhase 2
Study of Icalcaprant for major depressive disorder
This trial tests an oral medication called icalcaprant for adults with major depressive disorder (MDD). It aims to see if the drug can reduce depression symptoms and what side effects may occur.
Atlanta, GeorgiaAges 18–65 - NCT06605105Enrolling by invitationPhase 3
Long-term extension trial of CYB003 for depression
This long-term study is for people who already completed an earlier trial of the experimental drug CYB003 for major depression and who stayed on their regular antidepressant. It looks at the safety and effects of taking CYB003 again over many months.
Atlanta, GeorgiaAges 18–85 - NCT05850689RecruitingPhase 3
Lumateperone add-on for major depression that didn’t improve
This study tests whether adding lumateperone to an antidepressant helps adults with major depressive disorder (MDD) who haven’t improved enough after trying at least two different antidepressants. It may help reduce depressive symptoms more than antidepressants alone.
Atlanta, GeorgiaAges 18–65 - NCT05548244Recruiting
Testing behavioral activation for teens with depression
This study looks at how a therapy approach called behavioral activation may affect depression in teens. It also uses brief daily check-ins on a phone to understand what changes during treatment.
Atlanta, GeorgiaAges 15–17
Hear when a new Depression trial opens near Atlanta, GA
We’ll email you when one opens near Atlanta, GA — at most once a week, no account needed, unsubscribe anytime.
Depression trials in other cities
Where these studies are running near Atlanta
Institutions with a site for the recruiting depression studies listed above.
- Emory University · 10 studies
- CenExel iResearch, LLC · 6 studies
- Advanced Discovery Research · 4 studies
- Synexus Clinical Research · 4 studies
- Grady Health System · 3 studies
- Psych Atlanta · 3 studies
- Atlanta Center for Medical Research · 2 studies
- DelRicht Research · 2 studies
What taking part in a depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting depression studies in Georgia.
Common questions
- Are there depression clinical trials near Atlanta?
- Yes. We're currently tracking 46 recruiting depression studies with a site near Atlanta, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depression study near Atlanta?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Atlanta to take part?
- Not necessarily. These studies have a site near Atlanta, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depression studies open near Atlanta regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.