Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT07665424Recruiting
Study of a bone filling device for spine fractures
This trial tests a device called Vessel-X to treat broken vertebrae (spine bones) caused by osteoporosis or injury. It aims to see if the device is safe and helps stabilize the spine.
TaipeiAges 40–95 - NCT07666555RecruitingPhase 2
Culmerciclib rechallenge for HR+ HER2- breast cancer
This trial tests a new drug called Culmerciclib for women with advanced HR-positive, HER2-negative breast cancer that has stopped responding to a CDK4/6 inhibitor with hormone therapy. The goal is to see if giving this drug again can help when other treatments no longer work.
ShanghaiAges 18–75 - NCT07669454RecruitingPhase 3
Nuvastatic® for metastatic colorectal cancer
This trial tests a new capsule (Nuvastatic®) added to standard chemotherapy for people with metastatic colorectal cancer. The goal is to see if it helps shrink tumors and improve well-being.
Visakhapatnam, Andhra PradeshAges 18–65 - NCT07670468RecruitingPhase 1/Phase 2
T-cell therapy for resistant viral infections after transplant or cancer treatment
This trial tests a special T-cell treatment (LB-DTK-MV) for people with virus infections (CMV, BKV, EBV) that did not get better with standard medicines. It is for patients who had a stem cell transplant or certain cancer therapies like CAR-T or bispecific antibodies.
SeoulAges 19 years+ - NCT07670702Enrolling by invitationPhase 3
Long-term safety and effectiveness of TSND-201 for PTSD
This trial checks the long-term safety and how well TSND-201, a study drug, helps people with PTSD. It is for patients who already completed a previous TSND-201 study and did well.
Orlando, FloridaAges Any age - NCT07657052Enrolling by invitation
Long-term safety and effectiveness of XH-S003 for PNH
This study tests if the drug XH-S003 is safe and works well over a long period for people with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease. If you've already taken XH-S003 in a past study and your doctor thinks it helped, you may join to keep getting the treatment.
Tianjin, JinanAges 18 years+ - NCT07656090Enrolling by invitationEarly Phase 1
Testing IDOV-Immune for advanced solid tumors
This trial tests an investigational drug called IDOV-Immune for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT07619924Enrolling by invitationEarly Phase 1
Phage Cocktail for Hard-to-Treat Skin Infections
This study tests a new treatment called a phage cocktail (viruses that kill bacteria) for skin infections caused by bacteria that don't respond well to regular antibiotics. The treatment is applied directly to the wound to see if it's safe and effective.
Xi'an, ShaanxiAges 18–75 - NCT07615309Enrolling by invitation
Omadacycline for Mycobacterium abscessus lung infection
This trial tests whether omadacycline (an antibiotic) can safely and effectively treat a rare lung infection caused by Mycobacterium abscessus bacteria. If you have this infection, this study may help doctors understand if this antibiotic works better than current treatments.
BeijingAges 18 years+ - NCT07547254Enrolling by invitation
Palmitoleic Acid Oil for Preventing Pressure Sores
This trial tests whether a special oil applied to the skin can prevent pressure injuries (bedsores) in patients at high risk. You would be screened using a skin moisture sensor to confirm your risk level.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07543094Enrolling by invitation
Brain Stimulation for Early Alzheimer's Memory and Thinking
This study tests whether a special type of brain stimulation called temporal interference stimulation can improve memory and thinking skills in people with early-stage Alzheimer's disease. The treatment uses electrical stimulation to target specific brain areas without surgery.
Shanghai, Shanghai MunicipalityAges 50–75 - NCT07527975Enrolling by invitation
Long-term safety and benefit check-up for RP-L102 gene therapy
This is a follow-up study for patients who previously received RP-L102, an experimental gene therapy designed to treat Fanconi anemia by fixing a faulty gene. The study tracks how well the treatment continues to work and watches for any long-term side effects.
Palo Alto, CaliforniaAges Any age - NCT07522385Enrolling by invitation
Endoscopic ultrasound treatment for gallstones while keeping gallbladder
This study tests a minimally invasive procedure that uses ultrasound guidance to create a small opening between your gallbladder and stomach or small intestine, allowing gallstones to pass without removing your gallbladder. It may help if you have symptoms from gallstones but want to preserve your gallbladder.
Wuhan, HubeiAges 18–80 - NCT07514741Enrolling by invitation
Testing a Prebiotic Blend in Healthy Adults
This study tests whether a prebiotic blend (a type of fiber supplement that feeds beneficial gut bacteria) is safe and works well in healthy people. You'll take the supplement daily for a set period while wearing a fitness tracker to see if it affects your health and activity.
West Hollywood, CaliforniaAges 18–60 - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT07488572Enrolling by invitationPhase 2
AK112 for advanced clear cell kidney cancer
This study tests a new drug called AK112 (Yiwoxidan Anti) in people with advanced clear cell kidney cancer who cannot take TKI medications. The goal is to see if it is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT07488312Enrolling by invitationPhase 1
Leucine-restricted diet for gastric cancer patients
This trial tests if a diet low in leucine (an amino acid) can help treat gastric cancer before surgery. It aims to see if it's safe and effective for patients who are preparing for tumor removal.
Jinan, ShandongAges 18–70 - NCT07456826Enrolling by invitationPhase 4
Comparing two eye numbing gels for shots
This trial tests a new eye-numbing gel against the standard numbing method to see which works better for patients getting regular anti-VEGF injections in the eye.
Tyler, TexasAges 18 years+ - NCT07398872Enrolling by invitationPhase 1
Gene therapy trial for children with ML4
This trial tests a gene therapy given by a one-time injection into the spinal fluid for children with Mucolipidosis type IV. It aims to see if the therapy is safe and can help slow or stop the disease.
Hangzhou, ZhejiangAges 1.5 years–8 years - NCT07395232RecruitingPhase 3
Testing a new drug for allergic eye disease (AKC)
This study tests a new medication called DFL24498 for people with atopic keratoconjunctivitis (AKC), a severe allergic eye condition. The goal is to see if it reduces itching, discomfort, and eye redness safely.
Jacksonville, FloridaAges 18–65 - NCT07371247Enrolling by invitationEarly Phase 1
Adjuvant treatment guided by ctDNA after chemoradiation for esophageal cancer
This trial tests whether adjusting treatment based on a blood test (ctDNA) after standard chemoradiation can improve outcomes for patients with advanced esophageal squamous cell carcinoma. It aims to find a more personalized approach to prevent cancer recurrence.
Nanjing, JiangsuAges 18–80 - NCT07334587Enrolling by invitation
Comparing two chemotherapies for advanced colorectal cancer
This trial compares two chemotherapy drug combinations (FOLFOX-6 and CAPOX) to see which works better and has fewer side effects for people with colorectal cancer that has spread. It may help you and your doctor choose the best treatment option.
Lahore, Punjab ProvinceAges 20–70 - NCT07221773Enrolling by invitation
Microneedling with Xvie gel for thinning hair in women
This trial tests whether a new gel called Xvie, delivered into the scalp with tiny needles (microneedling), can help women who feel their hair is thinning. You will get the treatment in a clinic, and the study will see if it makes your hair look fuller.
Maitland, FloridaAges 28–65
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.